膀胱电针治疗脊髓病变神经源性尿潴留的疗效观察

目的:观察膀胱电针治疗脊髓病变患者尿潴留的疗效。方法:脊髓病变伴尿潴留患者72例,按意愿分为观察组42例和对照组30例,2组均给予常规治疗,观察组还给予膀胱电针治疗。观察2组治疗前后尿潴留改善情况,评估2组生活质量。结果:治疗后,2组膀胱残余尿明显减少(P<0.05),观察组的残余尿量低于对照组(P<0.05)。观察组和对照组的总有效率分别为95.2%、66.7%,2组疗效比较有显著性差异(P<0.01)。治疗后,观察组的生存质量明显好于对照组,有显著性差异(P<0.01)。结论:膀胱电针能有效地改善脊髓病变患者膀胱功能,减轻尿潴留。

膀胱电针刺激结合晶珠前列癃闭通胶囊治疗良性前列腺增生疗效观察

目的观察膀胱电针刺激结合晶珠前列癃闭通胶囊治疗良性前列腺增生的临床效果。方法将102例良性前列腺增生患者随机分为对照组和观察组各51例,其中对照组给予晶珠前列癃闭通胶囊治疗,观察组给予膀胱电针刺激结合晶珠前列癃闭通胶囊治疗,2组均以4周为1个疗程。观察2组治疗后的临床效果。结果观察组治疗总有效率明显高于对照组(P<0.05);治疗后2组国际前列腺症状评分、生活质量评分及各中医症状评分均较治疗前明显降低(P均<0.05),最大尿流率均较治疗前明显升高(P<0.05),且观察组各指标改善程度明显优于对照组(P均<0.05)。结论膀胱电针刺激结合晶珠前列癃闭通胶囊治疗良性前列腺增生可明显提高临床疗效,改善患者临床症状及预后。

电针膀胱俞联合抗生素治疗绝经后妇女慢性尿路感染疗效观察

目的 :观察电针膀胱俞联合抗生素治疗绝经后妇女慢性尿路感染的临床疗效。方法 :收集2013年1月至2015年6月中心门诊及住院绝经后慢性尿路感染患者80例,分为治疗组和对照组各40例,两组均每天1次口服左氧氟沙星胶囊0.5 g,治疗组加用膀胱俞电针治疗,每周3次,每次30 min,疗程为2周。治疗结束后比较两组治疗前后的临床疗效及中医证候积分。结果 :治疗组和对照组的治疗有效率分别为91.89%和67.64%,差异有统计学意义(P<0.05);两组治疗后中医证候积分值均有下降,与治疗前比较差异均有统计学意义(P<0.01)。治疗前后两组中医证候积分差值比较,治疗组高于对照组,差异有统计学意义(P<0.01)。结论 :电针膀胱俞治疗绝经后妇女慢性尿路感染疗效确切,有利于症状改善。

Clinical Observations on Electroacupuncture Treatment of Unstable Bladder

Objective： To assess the clinical efficacy of electroacupuncture for treatment of unstable bladder. Methods： Patients were randomly divided into electroacupuncture and control groups and the curative effects were evaluated according to improvement in clinical symptom and quality of life scores after treatment. Results： The observation indices were significantly lower after than before treatment in both groups （P〈0.05）. There was no significant difference in clinical symptom score between the two groups （P〉0.05）. Quality of life score was significantly decreased in the electroacupuncture group as compared with that in the manipulation group （P〈0.05）. Conclusion： Both treatments improve voiding difficulty. The degree of satisfaction to quality of life is larger in the electroacupuncture group than in the manipulation group. Clinical symptom score tends to be lower in the electroacupuncture group than in the manipulation group.

Effect of Electroacupuncture on the Bladder Function in Rats with Bladder Hyperactivity

Objective： To investigate the neurobiological mechanism of electroacupuncture in inhibiting bladder hyperactivity induced by L-dopa by observing frequency of urination and expression of vasoactive intestinal peptide （VIP） in sacral dorsal horn. Methods： Forty-eight rats were allocated with a random number table into normal group （n=6）, control group （n=14）, model group （n=14）, and electroacupuncture group （n=14）. All rats were treated with bladder encheiresis. Rats in the normal group were not given injection. Rats in the control group were intraperitoneally injected with physiological saline. Rats in the model and electroacupuncture groups were intraperitoneally injected with Carbidopa and L-dopa. Continuous cystometry was performed to observe the effect of electroacupuncture on urination frequency. Dynamic changes of VIP in the sacral dorsal horn were measured by immunohistochemistry and quantitative image analysis after electroacupuncture. Results： In rats of model group, urination frequency increased after treatment （P〈0.05）, in rats of electroacupuncture group, it increased at 15-75 min after L-dopa injection than that before treatment （P〈0.05）, and was same as that before treatment at 75-105 min after L-dopa injection. Positive fiber and end of VIP in the sacral dorsal horn of rats in the electroacupuncture group were more than those in the normal and model groups at 3 h after L-dopa injection （P〈0.05）, and was more than those in the normal group at 8 h after L-dopa injection （P〈0.05）, and there was no significant difference between electro-acupuncture and normal groups. Conclusion： Electroacuptmcture can promote the release of VIP from afferent nerves in rats with L-dopa-induced bladder hyperactivity to decrease urination frequency.