Objective:To study the characteristics of the intraocular lens using ion beam sputtering depositing titanium nitride thin film on the intraocular lens(IOLs).Methods:To deposite titanium nitride thin film on the top of...Objective:To study the characteristics of the intraocular lens using ion beam sputtering depositing titanium nitride thin film on the intraocular lens(IOLs).Methods:To deposite titanium nitride thin film on the top of intraocular lens by ion beam sputtering depositing.We analyzed the surface morphology of intraocular lens through SEM and AFM.We detected intraocular lens resolution through the measurement of intraocular lens.Biocompatibility of intraocular lens is preliminary evaluated in this test.Results:The surface morphology of intraocular lens material was not changed,and was in line with the requirements of smoothness.Resolution was in line with national requirements.Unmodified and modified IOLs's cytotoxicity were 1 and 0.6 grade respectively.Hemolytic rates of modified and unmodified were both less than 5%.Conclusion:Ion beam sputtering deposition of objects didn't only affect the surface morphology and the basic optical performance,but also can enhance the biocompatibility of intraocular lens.Ion beam sputtering deposition technique has provided new methods for the surface modification of IOLs and PMMA materials.展开更多
Graphene oxide(GO) has been demonstrated to be an effective hydrophilic nanofiller to modify the polymeric membranes when forming a mixed matrix structure. GO quantum dots(QDs) are promising candidates to fully exert ...Graphene oxide(GO) has been demonstrated to be an effective hydrophilic nanofiller to modify the polymeric membranes when forming a mixed matrix structure. GO quantum dots(QDs) are promising candidates to fully exert the rich oxygen containing functional groups due to their unique size induced edge effects. In this work, GO QDs modified polysulfone(PSF) ultrafiltration(UF) membranes were prepared by phase inversion method with various GO QDs loadings(0.1–0.5 wt.%). A proper amount of GO QDs addition led to a more porous and hydrophilic membrane structure. With 0.3 wt.% GO QDs, the membranes showed a60% increase in permeability(130.54 vs. 82.52 LMH bar^-1).The pristine PSF membranes had a complete cutoff of bovine serum albumin molecules and it was well maintained with GO QDs incorporated. The membranes with 0.5 wt.% GO QDs exhibited the highest flux recovery ratio of 89.7% and the lowest irreversible fouling of 10.3%(54.5% and 33.3% for the pristine PSF membranes). Our results proved that GO QDs can function as effective nanofillers to enhance the hydrophilicity, permeability and antifouling performance of PSF UF membranes.展开更多
文摘Objective:To study the characteristics of the intraocular lens using ion beam sputtering depositing titanium nitride thin film on the intraocular lens(IOLs).Methods:To deposite titanium nitride thin film on the top of intraocular lens by ion beam sputtering depositing.We analyzed the surface morphology of intraocular lens through SEM and AFM.We detected intraocular lens resolution through the measurement of intraocular lens.Biocompatibility of intraocular lens is preliminary evaluated in this test.Results:The surface morphology of intraocular lens material was not changed,and was in line with the requirements of smoothness.Resolution was in line with national requirements.Unmodified and modified IOLs's cytotoxicity were 1 and 0.6 grade respectively.Hemolytic rates of modified and unmodified were both less than 5%.Conclusion:Ion beam sputtering deposition of objects didn't only affect the surface morphology and the basic optical performance,but also can enhance the biocompatibility of intraocular lens.Ion beam sputtering deposition technique has provided new methods for the surface modification of IOLs and PMMA materials.
基金supported by Beijing Natural Science Foundation(2172027)
文摘Graphene oxide(GO) has been demonstrated to be an effective hydrophilic nanofiller to modify the polymeric membranes when forming a mixed matrix structure. GO quantum dots(QDs) are promising candidates to fully exert the rich oxygen containing functional groups due to their unique size induced edge effects. In this work, GO QDs modified polysulfone(PSF) ultrafiltration(UF) membranes were prepared by phase inversion method with various GO QDs loadings(0.1–0.5 wt.%). A proper amount of GO QDs addition led to a more porous and hydrophilic membrane structure. With 0.3 wt.% GO QDs, the membranes showed a60% increase in permeability(130.54 vs. 82.52 LMH bar^-1).The pristine PSF membranes had a complete cutoff of bovine serum albumin molecules and it was well maintained with GO QDs incorporated. The membranes with 0.5 wt.% GO QDs exhibited the highest flux recovery ratio of 89.7% and the lowest irreversible fouling of 10.3%(54.5% and 33.3% for the pristine PSF membranes). Our results proved that GO QDs can function as effective nanofillers to enhance the hydrophilicity, permeability and antifouling performance of PSF UF membranes.
