目的:开发头颈癌患者自我感知歧视量表(head and neck cancer self-perceived discrimination scale,HNCSPDS),检验其信效度及适用性,并分析患者自我感知歧视与生活质量的相关性。方法:采用经典测量理论,选取326例头颈癌患者开发HNCSPDS...目的:开发头颈癌患者自我感知歧视量表(head and neck cancer self-perceived discrimination scale,HNCSPDS),检验其信效度及适用性,并分析患者自我感知歧视与生活质量的相关性。方法:采用经典测量理论,选取326例头颈癌患者开发HNCSPDS;Delphi专家咨询和条目分析用来提升HNCSPDS的内容效度;采用因子分析(factor analysis,FA)和结构方程模型(structural equation modeling,SEM)检验HNCSPDS的结构效度,采用Cronbach's alpha系数、Spearman-Brown系数和组内相关系数(intra-class correlation coefficient,ICC)检验HNCSPDS的内部一致性和重测可靠性;采用多元逐步线性回归分析患者自我感知歧视的危险因素,采用Pearson相关系数分析自我感知歧视与生活质量的相关性。结果:HNCSPDS共14个条目,包括3个维度(形象污名、社交隔离和自我贬低),具有良好的效度(χ^(2)/df=2.311,RMSEA=0.064,GFI=0.937,AGFI=0.904,CFI=0.972,NFI=0.957,IFI=0.972,TLI=0.963)、信度(Cronbach'sα系数为0.957,分半信度为0.967,重测信度为0.878)和适用性[平均完成时间(14.33±2.315)min和93.14%的有效完成率]。经济负担和性别是患者自我感知歧视的独立危险因素(P<0.01),自我感知歧视与生活质量呈负相关。结论:头颈癌患者普遍存在较强的自我感知歧视,HNCSPDS在自我感知歧视测量中信效度良好,为将来预防和缓解患者自我感知歧视心理,提高患者身心健康和生活质量提供科学有效的评估工具。展开更多
Introduction-The aim of this multicenter study was to validate the French version of the fecal incontinence quality-of-life scale (FIQL scale) developed in the Unites States of America.Patients and methods-The FIQL sc...Introduction-The aim of this multicenter study was to validate the French version of the fecal incontinence quality-of-life scale (FIQL scale) developed in the Unites States of America.Patients and methods-The FIQL scale has 29 items in four scales: lifestyle, coping/behavior, depression/self-perception and embarrassment. Each item is scored from 1 to 4, with poorest quality-of-life scored 1. An average is calculated for each scale. After linguistic validation of the questionnaire, the French version of the FIQL scale was tested twice, at day 0 and day 7, by 100 patients with fecal incontinence (FI). Construction validity, internal reliability, clinical validity and reproducibility were analysed. Results-Analysis of convergent validity of the French version of the FIQL scale showed very good correlation between items and the corresponding scale for lifestyle (0.50-0.79)and depression/self-percep-tion (0.44-0.74), good correlation for coping/behavior (0.31-0.70) and weak correlation for embarrassment (0.30-0.40). Valid discrimination was observed for 24 of the 29 items. Internal reliability was good for each scale (a Cronbach between 0.78 and 0.92). Scores determined with the FIQL scale were significantly correlated with Wexner FI scores, demonstrating the clinical validity of the instrument. Reproducibility, evaluated in patients whose FI was unchanged between day 0 and day 7, was good with intraclass correlation coefficients ranging from 0.80 (embarrassment) to 0.93 (lifestyle). Conclusions-The linguistic and psychometric evaluation demonstrated the validity of the French version of the FIQL scale. This standardized instrument is now available for clinical use in France for quality-of-life assessment in patients with FI.展开更多
文摘Introduction-The aim of this multicenter study was to validate the French version of the fecal incontinence quality-of-life scale (FIQL scale) developed in the Unites States of America.Patients and methods-The FIQL scale has 29 items in four scales: lifestyle, coping/behavior, depression/self-perception and embarrassment. Each item is scored from 1 to 4, with poorest quality-of-life scored 1. An average is calculated for each scale. After linguistic validation of the questionnaire, the French version of the FIQL scale was tested twice, at day 0 and day 7, by 100 patients with fecal incontinence (FI). Construction validity, internal reliability, clinical validity and reproducibility were analysed. Results-Analysis of convergent validity of the French version of the FIQL scale showed very good correlation between items and the corresponding scale for lifestyle (0.50-0.79)and depression/self-percep-tion (0.44-0.74), good correlation for coping/behavior (0.31-0.70) and weak correlation for embarrassment (0.30-0.40). Valid discrimination was observed for 24 of the 29 items. Internal reliability was good for each scale (a Cronbach between 0.78 and 0.92). Scores determined with the FIQL scale were significantly correlated with Wexner FI scores, demonstrating the clinical validity of the instrument. Reproducibility, evaluated in patients whose FI was unchanged between day 0 and day 7, was good with intraclass correlation coefficients ranging from 0.80 (embarrassment) to 0.93 (lifestyle). Conclusions-The linguistic and psychometric evaluation demonstrated the validity of the French version of the FIQL scale. This standardized instrument is now available for clinical use in France for quality-of-life assessment in patients with FI.