Throughout history,surgeons have been on a quest to refine the surgical treatment options for their patients and to minimize operative trauma.During the last three decades,there have been tremendous advances in the fi...Throughout history,surgeons have been on a quest to refine the surgical treatment options for their patients and to minimize operative trauma.During the last three decades,there have been tremendous advances in the field of minimally invasive colorectal surgery,with an explosion of different technologies and approaches offered to treat well-known diseases.Laparoscopic surgery has been shown to be equal or superior to open surgery.The boundaries of laparoscopy have been pushed further,in the form of single-incision laparoscopy,natural-orifice transluminal endoscopic surgery and robotics.This paper critically reviews the pathway of development of minimally invasive surgery,and appraises the different minimally invasive colorectal surgical approaches available to date.展开更多
文摘目的探究采用腹腔镜结直肠癌标本经自然腔道取出术(natural orifice specimen extraction surgery,NOSES)治疗结直肠癌的临床疗效以及对患者氧化应激、炎症反应的影响。方法选择2018年3月至2019年11月于南阳市第二人民医院胃肠外科接受手术治疗的134例结直肠癌患者,并根据术式不同分为2组。其中观察组67例给予腹腔镜NOSES,对照组67例采用腹腔镜结直肠癌根治术,治疗后再对比2组手术相关指标、氧化应激以及炎症反应情况。结果观察组首次排气时间、术后住院时间分别为(26.32±3.13)h、(6.62±0.77)d,均显著低于对照组,差异有统计学意义(P<0.05);术后24 h 2组MDA均显著升高,SOD水平均显著降低,且观察组MDA升高幅度与SOD降低幅度均显著低于对照组,差异有统计学意义(P<0.05);术后24 h 2组TNF-α、CRP、IL-6水平均显著升高,IL-10水平显著降低,且观察组TNF-α、CRP、IL-6水平升高幅度与IL-10水平降低幅度显著低于对照组,差异有统计学意义(P<0.05)。结论结直肠癌患者采用腹腔镜NOSES能够有效改善氧化应激与炎症反应,术后康复效果显著。
文摘Throughout history,surgeons have been on a quest to refine the surgical treatment options for their patients and to minimize operative trauma.During the last three decades,there have been tremendous advances in the field of minimally invasive colorectal surgery,with an explosion of different technologies and approaches offered to treat well-known diseases.Laparoscopic surgery has been shown to be equal or superior to open surgery.The boundaries of laparoscopy have been pushed further,in the form of single-incision laparoscopy,natural-orifice transluminal endoscopic surgery and robotics.This paper critically reviews the pathway of development of minimally invasive surgery,and appraises the different minimally invasive colorectal surgical approaches available to date.
