自组方1号对小鼠酒精性肝损伤的干预作用

目的:研究自组方1号对小鼠酒精性肝损伤的影响。方法:采用50%乙醇灌胃造成小鼠酒精性肝损伤模型,检测血清中甘油三酯(TG)的含量的活性及肝组织丙二醛(MDA)、谷胱甘肽(GSH)含量,并进行肝脏病理组织学检查。结果:给予自组方后可使肝组织中MDA含量明显降低,血清TG含量降低,肝组织病理改变明显好转,且具有剂量依赖性,高剂量组与对照组大鼠的各项指标相似。结论:自组方1号对酒精性肝损伤有明显的保护作用。

自组方1号的毒理学安全性评价

目的:评价自组方1号的安全性。方法:依据毒理学评价程序和方法进行急性毒性试验、骨髓细胞微核试验、精子畸形试验、Ames试验和30天喂养试验。结果:小鼠经口MTD>15000mg/kg,属无毒物;骨髓细胞微核试验、精子畸形试验和Ames试验结果均为阴性;30天喂养试验中各项指标均未见异常。结论:在该试验条件下,自组方1号是安全的。

自组方与穴位贴敷结合治疗肺炎支原体感染后慢性咳嗽临床研究

目的:观察我院自组方联合穴位贴敷对儿童肺炎支原体感染后慢性咳嗽的疗效。方法:选择在我院接受治疗的120例肺炎支原体感染后慢性咳嗽患儿进行回顾性分析。根据患儿接受治疗方式的不同将其分为2组,行常规西医治疗57例为对照组,常规西医治疗基础上加以自组方与穴位贴敷结合治疗的63例为观察组。结果:观察组总有效率为95.25%,高于对照组的80.70%(P<0.05)。治疗后两组患者中医证候评分均明显下降,但观察组下降幅度更大,治疗后两组患者圣乔治呼吸问卷得分均明显升高,但观察组升高更明显(P<0.05)。治疗后两组患者CRP、TNF-α及IL-6水平均显著下降,但观察组下降幅度更大(P<0.05)。对照组共出现3例(5.26%)不良反应,与观察组的5例(7.94%)比较差异无统计学意义(P>0.05)。结论:常规西医治疗加以自组方与穴位贴敷结合治疗较单独常规西医治疗可有效提高儿童肺炎支原体感染后慢性咳嗽疗效,改善中医证候,提高患者生活质量且具有较高的安全性,其作用机制可能与缓解炎症反应有关。

Fabrication of titanium oxide films at low temperature from aqueous solution

Titanium oxide thin films were prepared on self-assembled monolayers-coated silicon substrate using layer-by-layer self-assembly method and chemical bath deposition from an aqueous solution. The effects of temperature on structural properties, thickness and morphologies of titanium oxide thin films were investigated. The results show that the absorption peak of peroxo complexes of titanium at 410 nm decreases gradually with increasing the temperature. The deposited films consisting of titanium oxide nanocrystals are believed to be fully amorphous by XRD. Titanium oxide thin films fabricated at 60 °C for 2 h are continuous, dense and homogeneous with a size in the range of 20-40 nm by SEM. The chemical compositions of deposited thin films were studied by EDS, and the mole ratio of O to Ti is 2.2：1.

Self-assembly and UV-curing Property of Polymerized Lyotropic Liquid Crystal Monomer of Sodium 3,4,5-tris（ll-acryloxyundecyloxy）benzoate

A polymerized lyotropic liquid crystal monomer of sodium 3,4,5-tris（11-acryloxyundecyloxy）- benzoate was synthesized by a convenient route starting from 3,4,5-trihydroxybenzoic acid via esterification followed by etherification, acylation and finally neutralization. The chemi- cal structure was confirmed by Fourier transform infrared （FT-IR） and 1H nuclear magnetic resonance spectral analysis. The self-organization behavior of the monomer with deionized water in methanol at room temperature was also demonstrated. The assemblies were char- acterized by polarized optical microscope and X-ray diffraction. The results show that a solution containing 80：20 of the monomer to water was found to be able to self-organize into Lamellar （La） phase and 92：8 with inverted hexagonal （H]I） phase, which was in ac- cordance with the theoretical calculation of critical packing parameter. It suggests that the concentration of the monomer was the key factor to influence assembly structure. Addi- tionally, the acrylate conversion with different photoinitiators and nanostructure retention after polymerization were investigated. The research shows that the acrylate conversion of the monomer with Darocur2959 could reach up to 78% when irradiated by 30 mW/cm2 UV light of 365 nm for 30 min characterized by Real-time FT-IR as well as the sol-gel method. Meanwhile, the La and HII phase nanostructures were both retained after polymerization.

Microwave-assisted ionothermal synthesis of hierarchical microcube-like BiOBr with enhanced photocatalytic activity

Bismuth oxybromide（BiOBr） with a hierarchical microcube morphology was successfully synthesized via microwave-assisted ionothermal self-assembly method. The as-obtained BiOBr was composed of regular multi-layered nanosheets, which were formed by selective adsorption of ionic liquids on the Br-terminated surface, followed by the formation of hydrogen bond-co-π-π stacking.The synthesized BiOBr exhibited high activity, excellent stability, and superior mineralization ability in the photocatalytic degradation of organic dyes under visible light owing to its enhanced light absorbance and narrow bandgap. Furthermore, photo-generated electrons were determined to be the main active species by comparison with different trapping agents used in the photocatalytic reactions.

Fault Diagnosis in Chemical Process Based on Self-organizing Map Integrated with Fisher Discriminant Analysis

Fault diagnosis and monitoring are very important for complex chemical process. There are numerous methods that have been studied in this field, in which the effective visualization method is still challenging. In order to get a better visualization effect, a novel fault diagnosis method which combines self-organizing map (SOM) with Fisher discriminant analysis (FDA) is proposed. FDA can reduce the dimension of the data in terms of maximizing the separability of the classes. After feature extraction by FDA, SOM can distinguish the different states on the output map clearly and it can also be employed to monitor abnormal states. Tennessee Eastman (TE) process is employed to illustrate the fault diagnosis and monitoring performance of the proposed method. The result shows that the SOM integrated with FDA method is efficient and capable for real-time monitoring and fault diagnosis in complex chemical process.

Relay movement control for maintaining connectivity in aeronautical ad hoc networks

As a new sort of mobile ad hoc network(MANET), aeronautical ad hoc network(AANET) has fleet-moving airborne nodes(ANs) and suffers from frequent network partitioning due to the rapid-changing topology. In this work, the additional relay nodes(RNs) is employed to repair the network and maintain connectivity in AANET. As ANs move, RNs need to move as well in order to re-establish the topology as quickly as possible. The network model and problem definition are firstly given, and then an online approach for RNs' movement control is presented to make ANs achieve certain connectivity requirement during run time. By defining the minimum cost feasible moving matrix(MCFM), a fast algorithm is proposed for RNs' movement control problem. Simulations demonstrate that the proposed algorithm outperforms other control approaches in the highly-dynamic environment and is of great potential to be applied in AANET.

Fault diagnosis of rocket engine ground testing bed with self-organizing maps(SOMs)

To solve the fault diagnosis problem of liquid propellant rocket engine ground testing bed,a fault diagnosis approach based on self-organizing map(SOM)is proposed.The SOM projects the multidimensional ground testing bed data into a two-dimensional map.Visualization of the SOM is used to cluster the ground testing bed data.The out map of the SOM is divided to several regions.Each region is represented for one fault mode.The fault mode of testing data is determined according to the region of their labels belonged to.The method is evaluated using the testing data of a liquid-propellant rocket engine ground testing bed with sixteen fault states.The results show that it is a reliable and effective method for fault diagnosis with good visualization property.

DFT Study on the Intermolecular Substrate-mediated Interaction Energy in the Self-assembly of Alkanethiols on Silver

The B3LYP/LanL1MB and B3LYP/LanL2DZ methods for Ag atom in conjunction with the 6-31G（d） basis set for S, C and H atoms were used to optimize the geometries and calculate the energies for （SCH3）mAg20 （re=1-4）, respectively. A single molecular adsorption energy of （SCH3）m （rn=1-4） on Ag20 and the intermolecular substrate-mediated interaction energy were evaluated. The results revealed that there is a proportional relation between the single molecular adsorption energy and the substrate-mediated intermolecular interaction energy. The results qualitatively demonstrated the semi-empirical expression for the substratemediated interaction energy proposed previously by us is consistent with the results of the density functional theory.

The exciting and magical journey of components from compound formulae to where they fight

With its long-term empirical clinical practice and increasing number of health benefits reported,Chinese Materia Medica(CMM)is gaining increasing global acceptance.Importantly,the identification of chemical constituents in vitro and exposed forms in vivo is a prerequisite for understanding how CMM formulae prevent and treat diseases.This review systematically summarizes the exciting and magical journey of CMM components from compound formulae to where they fight,the possible structural transformation of CMM components in vitro and in vivo,and their pharmacological contribution.When a decoction is prepared,significant chemical reactions are observed,including degradation and production of polymers and self-assembling supramolecules,leading to the construction of a component library with diverse decoction structures.After ingestion,compounds pass through the intestinal and blood-brain barriers and undergo a more wonderful journey involving the gut microbiota,microbial enzymes,and endogenous drug-metabolizing enzymes(mainly liver enzymes).At this stage,they are modified and assembled into novel and complex compounds,such as newly generated metabolites,conjugates,and self-assembling superamolecules.This review might provide a strategic orientation to explore the active compounds of CMM formulae in vivo.

Self-organized Critical Model Based on Complex Brain Networks with Hierarchical Organization

The dynamical behavior in the cortical brain network of macaque is studied by modelling each cortical areawith a subnetwork of interacting excitable neurons.We find that the avalanche of our model on different levels exhibitspower-law.Furthermore the power-law exponent of the distribution and the average avalanche size are affected by thetopology of the network.

Combined method for parallel manipulator configuration design

Configuration design is an essential, creative and decision-making step m parallel manipulator design process, in which modeling and assembly are iterative and trivial. Combined approach with automatic parametric modeling and automatic assembly is proposed for parallel manipulator configuration design. The design process and key techniques, such as configuration design, configuration verification, poses calculation of all parts in parallel manipulator, virtual assembly and etc., are discussed and demonstrated by an example. A software package is developed for parallel manipulator configuration design based on the proposed method with Visual C＋＋ and UG/OPEN on Unigraphics.

Self-Organized Algorithm in LTE Networks： A Utility Function Based Optimal Power Control Scheme

In this paper, transmission power control problem for uplink LTE network is investigated and a new autonomic uplink power control scheme was proposed based on utility function, which is a self- organized algorithm. The whole approach is based on the economic concept named utility function. Then a self-organized algorithm is distributed in each mobile users to control the transmission power and to maximize the transmission utility. The proposed scheme is solved through the Lagrange multiplier technique. It is proved that the utility function based algorithm optimal power level can be model. is applicable and the achieved based on our

Exact Solutions of a Generalized Multi-Fractional Nonlinear Diffusion Equation in Radical Symmetry

This paper is devoted to investigating exact solutions of a generalized fractional nonlinear anomalousdiffusion equation in radical symmetry.The presence of external force and absorption is also considered.We firstinvestigate the nonlinear anomalous diffusion equations with one-fractional derivative and then multi-fractional ones.Inboth situations,we obtain the corresponding exact solutions,and the solutions found here can have a compact behavioror a long tailed behavior.

Application and Self-assembly of Semiconductor Nanowire

The unique properties of semiconductor nanowires are introduced,and recent research progresses in application,self-assembly synthesis methods and mechanisms are summarized.

Automatic Migration of a Software Task to Hardware Component in MPSoC Systems

The authors will focus on the study of the design of Multiprocessor Systems on Chip （MPSoC）, specifically in the context of improving the performance of applications located on the MPSoC architecture. The objective of this research is to study the problems of transition from a pure software implementation for an embodiment admitting one or more hardware components and to develop a methodology for automatic generation of migration of a software task into a hardware component in MPSoC. The transformation of a software task into a hardware task led to many changes, hardware part （connection, the requirement of an interrupt controller...）, software part （at least one task, I/O （I/O）, synchronization...） and an architectural point of view, the remarkable aspects of data storage. The experiment is done on the MJPEG decoder to illustrate the effectiveness of the authors＇ tool for automatic generation of migration.

Seismic Waves in Layered Media

This paper is organized as follows. After a discussion of the differential equations for wave propagation in the horizontally stratified medium and of the initial and boundary conditions, the displacements are derived on the free surface of the layered medium for plane waves when a point source is located on the s-th imaginary boundary at the depth -s （physical parameters of the layers s and （s ＋ 1） are put to be identical）. Then, the source will be represented as a single force of arbitrary orientation and a general moment tensor point source. Further, ＂a primary field＂ for a point source will be introduced. Matrix method for the solution of the direct seismic problem is considered based on the matrix method of Thomson-Haskell and its modifications.

An Empirical Study on the 1 ＋ 1 Model in College English Listening and Speaking Class

Improving college students＇ listening and speaking ability is a very important part of college English teaching Based on the foreign and domestic studies on how to improve students＇ listening and speaking ability, this paper explores the 1 ＋ 1 model in listening and speaking class, which is to divide the listening and speaking class into two parts--small speaking class combined with students＇ online autonomous learning. Through one-year experiment and study on two classes, although there is no significant difference between the performances of these classes, this study has shed some light on how to vary the teaching methods, how to improve the class efficiency, students＇ autonomy in leaming, and how to build new assessment system. Further studies could be made later based on this

Bicharacteristic Curves in Modeling of the Earth Crust and Upper Mantle

The aim of this paper is the introduction of a new approach to 3D modelling of elastic piecewise homogeneous media, in particular Earth crust and upper Mantle. The method is based on the principle of tomography with Earthquake as a source of the signal and receiver stations on the surface. The wave propagation in solid media is described by a system of three strongly coupled hyperbolic equations with piece - wise constant coefitients. The characteristic set and hi-characteristic curves of this system are computed in a homogeneous half-space with free boundary and the formulae of reflection and diffraction of the hi-characteristics on the internal boundaries of the media. Applications of the characteristic set and bi-eharacteristic curves for the inverse problem in geophysics and Earth modelling are given.