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自拟舒肝益肾方联合内分泌治疗激素依赖型乳腺癌疗效
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作者 王成 王晓玲 +2 位作者 李江涛 汪旻琦 赵莉娜 《辽宁中医杂志》 CAS 2023年第8期115-119,共5页
目的探讨自拟舒肝益肾方联合内分泌治疗激素依赖型乳腺癌疗效分析。方法选取该院2018年1月—2020年1月70例激素受体阳性乳腺癌内分泌治疗患者,随机分为观察组与对照组,每组各包括35例患者,对照组给予内分泌治疗,观察组应用舒肝益肾方联... 目的探讨自拟舒肝益肾方联合内分泌治疗激素依赖型乳腺癌疗效分析。方法选取该院2018年1月—2020年1月70例激素受体阳性乳腺癌内分泌治疗患者,随机分为观察组与对照组,每组各包括35例患者,对照组给予内分泌治疗,观察组应用舒肝益肾方联合内分泌治疗,比较两组治疗3个月后的临床疗效、临床症状改善、肿瘤标志物、Th1/Th2细胞因子水平、内分泌治疗相关不良反应以及随访2年生存情况。结果观察组治疗有效率94.29%高于对照组74.29%(P<0.05);观察组治疗后乳房胀痛、情志抑郁、腰膝酸软、头晕目眩、两胁作痛、食欲不振、二便不调症状评分均低于对照组(P<0.05);观察组治疗后肿瘤标志物糖类抗原153(CA153)、糖类抗原125(CA125)、癌胚抗原(CEA)以及血管内皮生长因子(VEGF)水平均低于对照组(P<0.05);观察组治疗后Th1细胞因子白细胞介素-2(IL-2)、肿瘤坏死因子α(TNF-α)、γ-干扰素(IFN-γ)水平高于对照组,Th2细胞因子白细胞介素-4/-8/-10(IL-4/-8/-10)水平低于对照组,Th1/Th2比值高于对照组(P<0.05);观察组治疗后血脂水平低于对照组,子宫内膜厚度小于对照组,骨密度值大于对照组(P<0.05);随访2年,观察组2年无进展生存率为85.71%(30/35),总生存率为91.43%(32/35);对照组2年无进展生存率为77.14%(27/35),总生存率为85.71%(30/35),两组随访2年生存情况比较(P>0.05)。结论自拟舒肝益肾方联合内分泌治疗可有效改善激素依赖型乳腺癌患者临床症状,抑制肿瘤进展,调节Th1/Th2细胞因子平衡,减轻内分泌治疗导致的血脂升高、骨密度增加、子宫内膜增厚等不良反应。 展开更多
关键词 乳腺癌 激素依赖型 自拟肝益肾方 TH1/TH2型细胞因子 疗效
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中西医结合治疗对急性缺血性脑卒中患者预后的影响 被引量:12
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作者 吕志宇 李作孝 《中医药导报》 2015年第8期51-53,共3页
目的:探讨中西医结合治疗对急性缺血性脑卒中患者预后的影响。方法:采用随机、对照的方法,将120例急性缺血性脑卒中患者随机分为治疗组和对照组。其中对照组按指南给予西药及康复治疗,而治疗组采用西医联合自拟滋阴养血舒筋汤、针灸及... 目的:探讨中西医结合治疗对急性缺血性脑卒中患者预后的影响。方法:采用随机、对照的方法,将120例急性缺血性脑卒中患者随机分为治疗组和对照组。其中对照组按指南给予西药及康复治疗,而治疗组采用西医联合自拟滋阴养血舒筋汤、针灸及推拿的治疗,疗效判断指标包括随访期末死亡/残障率、神经功能缺损评分变化及肢体运动功能评分变化。结果:6个月随访期末,治疗组的死亡/残障率均低于对照组,差异有统计学意义(P=0.008)。治疗30 d后,治疗组的神经功能缺损评分较对照组改善更明显(P=0.000)。治疗30 d后,肢体运动功能FMA评分较对照组改善更显著,差异有统计学意义(P=0.004)。结论:中西医结合治疗方案可减少急性缺血性卒中患者致残率,改善其神经功能,提高其生存自理能力。 展开更多
关键词 急性缺血性卒中 运动功能 中西医结合 自拟滋阴养血筋汤 针灸 推拿
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唐代大文学家柳宗元的寂寞与风流
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作者 张健旺 《新余学院学报》 2016年第5期47-50,共4页
柳宗元是我国唐代大文学家。柳宗元的文章堪称绝美,他性情的核心是"风流"。柳宗元绽放的是审美"风流"精神。"风流"的本质就是一种审美超越感,柳宗元的审美超越感是一种审美救赎。他遭遇"万事瓦裂,... 柳宗元是我国唐代大文学家。柳宗元的文章堪称绝美,他性情的核心是"风流"。柳宗元绽放的是审美"风流"精神。"风流"的本质就是一种审美超越感,柳宗元的审美超越感是一种审美救赎。他遭遇"万事瓦裂,身残家破"的痛击,内在的失衡表现为他的精神危机、心理危机和生理损害。他并没有意志消沉,而是展现出"鼓勇以超泥途"自我拯救的魄力与英雄气,绽放出绝美的"风流"风格。 展开更多
关键词 柳宗元 自舒 著书 读禅 寂寞 风流
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Analysis and Comparison of Safety and Fatigue Comfort of Postal Bicycles Based on Finite Element Method and sEMG 被引量:5
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作者 项忠霞 李亚南 +1 位作者 田冠 常振元 《Transactions of Tianjin University》 EI CAS 2013年第4期272-278,共7页
The safety and the fatigue comfort were compared between a domestic and a Japanese postal bicycle. Firstly, the fatigue comfort of these two kinds of bicycles was evaluated by surface electromyographic signal (sEMG) e... The safety and the fatigue comfort were compared between a domestic and a Japanese postal bicycle. Firstly, the fatigue comfort of these two kinds of bicycles was evaluated by surface electromyographic signal (sEMG) experiment, in which human lower limb muscle groups were research objects, and the average EMG (AEMG) index and median frequency (MF) were chosen as the evaluation indexes. Secondly, the safety of these two kinds of bicycle frames was analyzed and compared by using the finite element analysis. The results show that the riding fatigue comfort of the Japanese postal bicycle is better, and the Japanese postal bicycle frame is more safe and reasonable although both the postal bicycles meet the requirement for strength. Finally, based on the above analysis, the frame structure and related parameters of the domestic postal bicycle were improved with reference to the Japanese postal bicycle and biomechanics theory. 展开更多
关键词 postal bicycle surface electromyogram signal evaluation index fatigue comfort finite element analysis
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Optimal Design of Mountain Bicycle Based on Biomechanics 被引量:1
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作者 卜研 黄田 +2 位作者 项忠霞 吴小凡 陈春 《Transactions of Tianjin University》 EI CAS 2010年第1期45-49,共5页
To achieve better cycling performance and vibration comfort of mountain bicycle, the optimization of frame structural parameters and rear suspension scale parameters is investigated based on biomechanics.Firstly, the ... To achieve better cycling performance and vibration comfort of mountain bicycle, the optimization of frame structural parameters and rear suspension scale parameters is investigated based on biomechanics.Firstly, the quadratic sum of rider lower limb muscles stresses is presented as the evaluation criterion of muscle fatigue.By taking the criterion as the objective function, the relative positions of three pivot points of frame are optimized to ensure that the frame structural parameters match the stature o... 展开更多
关键词 mountain bicycle BIOMECHANICS muscle fatigue vibration comfort optimum design
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Optimization of Five-Freedom Comfort Model of Vehicle
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作者 NI Jinshang 《International Journal of Technology Management》 2015年第1期87-89,共3页
In this paper, a planar five-freedom model of whole vehicle is set up and its corresponding sport differential equation is founded. The square root of the driver' s acceleration is selected as the estimate index by t... In this paper, a planar five-freedom model of whole vehicle is set up and its corresponding sport differential equation is founded. The square root of the driver' s acceleration is selected as the estimate index by the estimate way of vehicle' s comfort. The estimate index is minimized by optimization of fore-and-aft suspension' s stiffness and written with corresponding program. In the end, a model of comfort simulation by soitware of Simulink is found, and a temporal simulation for the upper example is applied to guessing the comfort of vehicle. 展开更多
关键词 COMFORT Square Root SIMULINK
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Adaptive Thermal Comfort for Occupants of Low-Cost Dwellings in a Hot Dry Climate
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作者 Irene Marincic J. Manuel Ochoa +1 位作者 M. Guadalupe Alpuche Gabriel Gomez-Azpeitia 《Journal of Civil Engineering and Architecture》 2012年第3期356-363,共8页
Adaptive models are based on the observation that there are some actions that people can and actually do take to achieve thermal comfort. Studies regarding thermal comfort conditions in economical dwellings were carri... Adaptive models are based on the observation that there are some actions that people can and actually do take to achieve thermal comfort. Studies regarding thermal comfort conditions in economical dwellings were carried out simultaneously in seven Mexican cities, corresponding to warm dry and warm humid climates. In this article, case studies of low-cost dwellings in the city of Hermosillo (in northwest Mexico), are presented and analyzed. Field surveys were carried out to obtain information about the physical characteristics of the dwellings and their occupants, as well as the indoor thermal environment. Neutral temperature was obtained from the applied survey. The high neutral temperature reveals the effect of inhabitants' adaptation mechanism to extreme climates. Occupant comfort votes as a function of indoor air temperatures were analyzed, and different characteristics such as age, size and gender were evaluated separately. The results show the variability of the neutral temperature and the tolerance to temperature changes, depending on the population's specific characteristics. In many cases where the population does not have access to artificial acclimatization devices, the neutral temperature values for specific climates and people can inform architects when choosing the most suitable thermal strategies for building design. 展开更多
关键词 Adaptive comfort low-cost dwelling hot dry climate.
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ABNORMAL LEFT VENTRICULAR SYSTOLIC AND DIASTOLIC FUNCTIONAL RESPONSE TO ISOMETRIC EXERCISE IN IDIOPATHIC DILATED CARDIOMY-OPATHY: BENEFICIAL EFFECT OF CAPTOPRIL
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作者 沈卫峰 张宪 +1 位作者 胡厚达 龚兰生 《Chinese Medical Sciences Journal》 CAS CSCD 1995年第4期232-236,共5页
In 19 patients with idiopathic dilated cardiomyopathy and symptoms of congetive heart failure, left ventricular (LV) systolic performance and diastolic velocity profiles were assessed by two- dimensional echocardiogra... In 19 patients with idiopathic dilated cardiomyopathy and symptoms of congetive heart failure, left ventricular (LV) systolic performance and diastolic velocity profiles were assessed by two- dimensional echocardiography and pulsed wave Doppler at rest and during handgrip exercise before and ninety minutes after administration of captopril (mean dose 25 +12mg; range 12. 5─50mg). Although heart rate and blood pressure increased similarly during handgrip exercise before and after captopril treatment, both were lower with handgrip exercise during captopril treatment. The results from this study indicated that acute angiotensin converting enzyme inhibition with captopril reduces preload and afterload and ameliorates handgrip exercise-induced LV systolic and diastolic filling dysfunction in patients with congestive heart failure secondary to idiopathic dilated cardiomyopathy. 展开更多
关键词 CARDIOMYOPATHY ECHOCARDIOGRAPHY CAPTOPRIL
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Model predictive control for adaptive cruise control with multi-objectives: comfort,fuel-economy,safety and car-following 被引量:34
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作者 Li-hua LUO Hong LIU Ping LI Hui WANG 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2010年第3期191-201,共11页
For automated vehicles,comfortable driving will improve passengers’ satisfaction.Reducing fuel consumption brings economic profits for car owners,decreases the impact on the environment and increases energy sustainab... For automated vehicles,comfortable driving will improve passengers’ satisfaction.Reducing fuel consumption brings economic profits for car owners,decreases the impact on the environment and increases energy sustainability.In addition to comfort and fuel-economy,automated vehicles also have the basic requirements of safety and car-following.For this purpose,an adaptive cruise control (ACC) algorithm with multi-objectives is proposed based on a model predictive control (MPC) framework.In the proposed ACC algorithm,safety is guaranteed by constraining the inter-distance within a safe range; the requirements of comfort and car-following are considered to be the performance criteria and some optimal reference trajectories are introduced to increase fuel-economy.The performances of the proposed ACC algorithm are simulated and analyzed in five representative traffic scenarios and multiple experiments.The results show that not only are safety and car-following objectives satisfied,but also driving comfort and fuel-economy are improved significantly. 展开更多
关键词 Adaptive cruise control (ACC) Multi-objectives Comfort Fuel-economy Model predictive control (MPC)
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