A fuzzy neural network controller with the teaching controller guidance and parameter regulations for vector-controlled induction motor is proposed. The design procedures of the fuzzy neural controller and the teachin...A fuzzy neural network controller with the teaching controller guidance and parameter regulations for vector-controlled induction motor is proposed. The design procedures of the fuzzy neural controller and the teaching controller are described. The parameters of the membership function are regulated by an on-line learning algorithm. The speed responses of the system under the condition, where the target functions are chosen as I qs and ω, are analyzed. The system responses with the variant of parameter moment of inertial J, viscous coefficients B and torque constant K tare also analyzed. Simulation results show that the control scheme and the controller have the advantages of rapid speed response and good robustness.展开更多
This paper explores the convergence of a class of optimally conditioned self scaling variable metric (OCSSVM) methods for unconstrained optimization. We show that this class of methods with Wolfe line search are glob...This paper explores the convergence of a class of optimally conditioned self scaling variable metric (OCSSVM) methods for unconstrained optimization. We show that this class of methods with Wolfe line search are globally convergent for general convex functions.展开更多
Aiming at alkaline problem of bauxite residue,this work focused variation of alkaline characteristics in bauxite residue through phosphogypsum treatment.The results demonstrated that the pH of bauxite residue reduced ...Aiming at alkaline problem of bauxite residue,this work focused variation of alkaline characteristics in bauxite residue through phosphogypsum treatment.The results demonstrated that the pH of bauxite residue reduced from initial 10.83 to 8.70 when 1.50 wt%phosphogypsum was added for 91 d.The removal rates of free alkali and exchangeable sodium were 97.94%and 75.87%,respectively.Meanwhile,significant positive correlations(P<0.05)existed between pH and free alkali,exchangeable sodium.The effect of free alkali composition was CO3^2–>OH^–>AlO2^–>HCO3^–.In addition,alkaline phase decreased from 52.81%to 48.58%and gypsum stably presented in bauxite residue which continuously provided Ca^2+to inhibit dissolution of combined alkali.Furthermore,phosphogypsum promoted formation of macroaggregate structure,increased Ca^2+,decreased Na+and Al^3+on the surface of bauxite residue significantly,ultimately promoting soil formation in bauxite residue.展开更多
Objective: Some animal models apply morphine in the drinking water to generate addiction, but related reports are not free of conflicting results. Accordingly, this study aimed to figure out if chronic consumption of...Objective: Some animal models apply morphine in the drinking water to generate addiction, but related reports are not free of conflicting results. Accordingly, this study aimed to figure out if chronic consumption of morphine in the drinking water can induce morphine addiction in Wistar rats. Methods: For 3 weeks, the animals received a daily morphine dose of 35 mg/kg by offering a calculated volume of sugar water (5% sucrose) with morphine (0. l mg/ml) to each rat; animals receiving just sugar water served as controls. Immediately after the treatment phase, the tail immersion test was used to check for morphine tolerance, and all animals were then kept on tap water for one week (withdrawal phase). Afterwards, all rats were allowed to choose their drinking source by offering two bottles, containing sugar water without and with morphine, simultaneously for two days (preference phase). Results: While the chronic consumption of morphine led to a reduction in body weight and to morphine tolerance, the morphine-treated Wistar rats did not show any preference for the opiate-containing sugar water. Conclusion: Body weight loss and tolerance do not reveal a condition of drug craving, and current animal models should be re-evaluated regarding their potential to establish morphine addicted animals.展开更多
Programmed cell death plays an important role in maintaining homeostasis during animal development, and has been conserved in animals as different as nematodes and humans. Recent studies of Drosophila have provided va...Programmed cell death plays an important role in maintaining homeostasis during animal development, and has been conserved in animals as different as nematodes and humans. Recent studies of Drosophila have provided valuable information toward our understanding of genetic regulation of death. Different signals trigger the novel death regulators rpr, hid, and grim, that utilize the evolutionarily conserved iap and ark genes to modulate caspase function. Subsequent removal of dying cells also appears to be accomplished by conserved mechanisms. The similarity between Drosophila and human in cell death signaling pathways illustrate the promise of fruit mes as a model system to elucidate the mechanisms underlying regulation of programmed cell death.展开更多
Self-diffraction appears when the strong laser goes through two-dimensional material suspension,and this spatial self-phase modulation(SPPM)phenomenon can be used to measure nonlinear optical parameters and achieve op...Self-diffraction appears when the strong laser goes through two-dimensional material suspension,and this spatial self-phase modulation(SPPM)phenomenon can be used to measure nonlinear optical parameters and achieve optical switch.At present,the mechanism of SPPM is still ambiguous.The debate mainly focuses on whether the phenomenon is caused by the nonlinear refractive index of the two-dimensional material or the thermal effect of the laser.The lack of theory limits the dimension of the phase modulation to the radius of the diffraction ring and the vertical imbalance.Therefore,it is urgent to establish a unified and universal SSPM theoretical system of two-dimensional material.展开更多
A novel algorithm based on Radon-Ambiguity Transform (RAT) and Adaptive Signal Decomposition (ASD) is presented for the detection and parameter estimation of multicompo-nent Linear Frequency Modulated (LFM) signals. T...A novel algorithm based on Radon-Ambiguity Transform (RAT) and Adaptive Signal Decomposition (ASD) is presented for the detection and parameter estimation of multicompo-nent Linear Frequency Modulated (LFM) signals. The key problem lies in the chirplet estimation. Genetic algorithm is employed to search for the optimization parameter of chirplet. High estimation accuracy can be obtained even at low Signal-to-Noisc Ratio(SNR). Finally simulation results are provided to demonstrate the performance of the proposed algorithm.展开更多
The performances of nonlinear WDM systems with different duty cycle are compared by means of numerical simulation.The numerical results show that the optical pulse with duty cycle of 0.5 is superior to the conventiona...The performances of nonlinear WDM systems with different duty cycle are compared by means of numerical simulation.The numerical results show that the optical pulse with duty cycle of 0.5 is superior to the conventional NRZ modulation scheme.The conclusion is different from that of some references.The reason is that inter symbol interference is not included in some references.In fact,inter symbol interference plays an important role in nonlinear WDM system.Although the larger the duty cycle is ,the stronger the effect of the cross-phase modulation and self-phase modulation on nonlinear WDM is,however,the larger the duty cycle is,the stronger the inter symbol interference is.展开更多
A real-time auto-focusing system with auto-collimation method is introduced, which is used in auto-detecting the focus of the space camera with long focus. Auto-focusing is the key technique to ensure high quality in ...A real-time auto-focusing system with auto-collimation method is introduced, which is used in auto-detecting the focus of the space camera with long focus. Auto-focusing is the key technique to ensure high quality in space imaging. It can measure and compensate the defocus caused by the change of temperature and air pressure etc. in space. To solve the problem of auto-focusing with auto-collimation method of the camera whose axis is perpendicular to the ground, it is designed that two small caliber pentagonal prisms are placed in the area of aperture suitable to the camera’s relative aperture based on the theory of auto-focusing with auto-collimation, which can replace the big caliber plane reflector used in other cameras. Using the characteristic of pentagonal prism refracting light vertically, the target slit is imaged in CCD through the two-separated lens. It transforms the detecting of the axial defocusing quantity to the landscape orientation measurement of the faculae’s position in the direction of CCD pixels. The defocusing quantity is obtained by measuring the opposite position of the two faculae on the CCD. The Centroid method is adopted to measure the position of the auto-collimation faculae. The arithmetic error is analyzed especially, and the causation is given. Experiments show that this real-time auto-focusing system using centroid method is reliable and the focusing precision can reach ±0.01 mm.展开更多
This paper focuses on the design of the cross layer between the video application layer and the MIMO physical layer. MIMO physical layer research has promised an enormous increase in the capacity of wireless communica...This paper focuses on the design of the cross layer between the video application layer and the MIMO physical layer. MIMO physical layer research has promised an enormous increase in the capacity of wireless communication systems. Also MIMO wireless systems operate under fading conditions where the channel faces arbitrary fluctuations. Since the wireless channel changes over each coherence period, the capacity of the wireless channel, given the power constraints, changes. Hence to make efficient use of the available capacity one needs to adapt the video bit rate. However it is impossible to adapt at the application layer as changing the parameters of the video takes more time than the coherence period of the channel. In this paper we address this problem through a novel solution and also investigate its performance through a simulation study.展开更多
The fact that outburst traffic in industrial Ethemet was focused on that would bring self-similar phenomenon leading to the delay increase of the cyclical data, and a hybrid priority queue schedule model was proposed ...The fact that outburst traffic in industrial Ethemet was focused on that would bring self-similar phenomenon leading to the delay increase of the cyclical data, and a hybrid priority queue schedule model was proposed in which the outburst data was given the highest priority. Some properties of the self-similar outburst data were proved by network calculus, and its service curve scheduled by the switch was gained. And then the performance of the scheduling algorithm was obtained. The simulation results are close to those calculated by using network calculus model. Some results are of actual significance to the construction of switched industrial Ethernet.展开更多
For a permanent magnet synchronous motor(PMSM)model predictive current control(MPCC)system,when the speed loop adopts proportional-integral(PI)control,speed regulation is easily affected by motor parameters,resulting ...For a permanent magnet synchronous motor(PMSM)model predictive current control(MPCC)system,when the speed loop adopts proportional-integral(PI)control,speed regulation is easily affected by motor parameters,resulting in the inability to balance the system robustness and dynamic performance.A PMSM optimal control strategy combining linear active disturbance rejection control(LADRC)and two-vector MPCC(TV-MPCC)is proposed.Firstly,a mathematical model of a PMSM is presented,and the PMSM TV-MPCC model is developed in the synchronous rotation coordinate system.Secondly,a first-order LADRC controller composed of a linear extended state observer and linear state error feedback is designed to reduce the complexity of parameter tuning while linearly simplifying the traditional active disturbance rejection control(ADRC)structure.Finally,the conventional PI speed regulator in the motor speed control system is replaced by the designed LADRC controller.The simulation results show that the speed control system using LADRC can effectively deal with the changes in motor parameters and has better robustness and dynamic performance than PI control and similar methods.The system has a fast motor speed response,small overshoot,strong anti-interference,and no steady-state error,and the total harmonic distortion is reduced.展开更多
For more than two decades, immunologists have been using the so-called Th1/Th2 paradigm to explain most of the phenomena related to adaptive immunity. The Thl/Th2 paradigm implied the existence of two different, mutu-...For more than two decades, immunologists have been using the so-called Th1/Th2 paradigm to explain most of the phenomena related to adaptive immunity. The Thl/Th2 paradigm implied the existence of two different, mutu- ally regulated, CD4+ T helper subsets: Thl cells, driving cell-mediated immune responses involved in tissue damage and fighting infection against intracellular parasites; and Th2 cells that mediate IgE production and are particu- larly involved in eosinophilic inflammation, allergy and clearance of helminthic infections. A third member of the T helper set, IL-17-producing CD4+ T cells, now called Th17 cells, was recently described as a distinct lineage that does not share developmental pathways with either Thl or Th2 cells. The Th17 subset has been linked to autoimmune disorders, being able to produce IL-17, IL-17F and IL-21 among other inflammatory cytokines. Interestingly, it has been reported that there is not only a cross-regulation among Thl, Th2 and Th17 effector cells but there is also a di- chotomy in the generation of Th17 and T regulatory cells. Therefore, Treg and Th17 effector cells arise in a mutually exclusive fashion, depending on whether they are activated in the presence of TGF-β or TGF-β plus inflammatory cytokines such as IL-6. This review will address the discovery of the Th17 cells, and recent progress on their development and regulation.展开更多
The authors have investigated the pH and ionic strength response of self-assembled layers formed by adsorption of amphiphilic weak polyelectrolytes. Using the SFA (Surface Forces Apparatus) the authors measured forc...The authors have investigated the pH and ionic strength response of self-assembled layers formed by adsorption of amphiphilic weak polyelectrolytes. Using the SFA (Surface Forces Apparatus) the authors measured force-distance profiles of poly (isoprene)-poly (acrylic acid) block copolymers adsorbed on mica. Also by Atomic Force Microscopy the authors captured single polyelectrolyte molecule adsorbed on a surface. The effect of salt concentration (Cs) and pH upon the height of the brush layers was explored mainly by measuring the forces between two adsorbed polyelectrolyte brushes. At pH = 4 our results are in good agreement with the scaling prediction L0 ∝Cs-1/3 Changing the pH from 4 to 10 causes a remarkable swelling of the polymer layer, but only a weak dependence on salt concentration was detected at the higher pH. This can be attributed to the degree of dissociation, which depends on the local pH value. At low pH the polyelectrolyte chains have a low charge density, while on increasing the pH the degree of dissociation rises, and the increased charge density is followed by swelling of the adsorbed layer. The local concentration of ions in the brush is now greater than that of pH = 4 and approximately equivalent to 0.3 M. So the swelling is only weakly dependent on salt concentration in the range 0.01-1.0 M. The results demonstrate the tunable nature of such self-assembled polyelectroiyte brushes whose height and range of interactions, can be systematically controlled by adjusting the pH and ionic strength of the medium.展开更多
The effects of exercise on decision-making performance have been studied using a wide variety of cognitive tasks and exercise interventions. Although the current literature supports a beneficial influence of acute exe...The effects of exercise on decision-making performance have been studied using a wide variety of cognitive tasks and exercise interventions. Although the current literature supports a beneficial influence of acute exercise on cognitive performance, the mechanisms underlying this phenomenon have not yet been elucidated. We review studies that used single-pulse transcranial magnetic stimulation (TMS) to probe the excitability of motor structures during whole-body exercise and present a framework to account for the facilitating effects of acute exercise on motor processes. Recent results suggest that, even in the absence of fatigue, the increase in corticospinal excitability classically reported during submaximal and exhausting exercises may be accompanied by a reduction in intracortical inhibition. We propose that reduced intracortical inhibition elicits an adaptive central mechanism that counteracts the progressive reduction in muscle responsiveness caused by peripheral fatigue. Such a reduction would render the motor cortex more sensitive to upstream influences, thus causing increased corticospinal excitability. Furthermore, reduction of intracortical inhibition may account for the more efficient descending drive and for the improvement of reaction time performance during exercise. The adaptive modulation in intracortical inhibition could be implemented through a general increase in reticular activation that would further account for enhanced sensory sensitivity.展开更多
Various control systems for a robotic excavator named LUCIE (Lancaster University Computerized and Intelligent Excavator),were investigated. The excavator is being developed to dig trenches autonomously. One stumbling...Various control systems for a robotic excavator named LUCIE (Lancaster University Computerized and Intelligent Excavator),were investigated. The excavator is being developed to dig trenches autonomously. One stumbling block is the achievement of adequate,accurate,quick and smooth movement under automatic control. Here,both classical and modern approaches are considered,including proportional-integral-derivative (PID) control tuned by conventional Zigler-Nichols rules,linear proportional-integral-plus (PIP) control,and a novel nonlinear PIP controller based on a state-dependent parameter (SDP) model structure,in which the parameters are functionally dependent on other variables in the system. Implementation results for the excavator joint arms control demonstrate that SDP-PIP controller provides the improved performance with fast,smooth and accurate response in comparison with both PID and linearized PIP control.展开更多
文摘A fuzzy neural network controller with the teaching controller guidance and parameter regulations for vector-controlled induction motor is proposed. The design procedures of the fuzzy neural controller and the teaching controller are described. The parameters of the membership function are regulated by an on-line learning algorithm. The speed responses of the system under the condition, where the target functions are chosen as I qs and ω, are analyzed. The system responses with the variant of parameter moment of inertial J, viscous coefficients B and torque constant K tare also analyzed. Simulation results show that the control scheme and the controller have the advantages of rapid speed response and good robustness.
文摘This paper explores the convergence of a class of optimally conditioned self scaling variable metric (OCSSVM) methods for unconstrained optimization. We show that this class of methods with Wolfe line search are globally convergent for general convex functions.
基金Projects(41877511,41842020)supported by the National Natural Science Foundation of China
文摘Aiming at alkaline problem of bauxite residue,this work focused variation of alkaline characteristics in bauxite residue through phosphogypsum treatment.The results demonstrated that the pH of bauxite residue reduced from initial 10.83 to 8.70 when 1.50 wt%phosphogypsum was added for 91 d.The removal rates of free alkali and exchangeable sodium were 97.94%and 75.87%,respectively.Meanwhile,significant positive correlations(P<0.05)existed between pH and free alkali,exchangeable sodium.The effect of free alkali composition was CO3^2–>OH^–>AlO2^–>HCO3^–.In addition,alkaline phase decreased from 52.81%to 48.58%and gypsum stably presented in bauxite residue which continuously provided Ca^2+to inhibit dissolution of combined alkali.Furthermore,phosphogypsum promoted formation of macroaggregate structure,increased Ca^2+,decreased Na+and Al^3+on the surface of bauxite residue significantly,ultimately promoting soil formation in bauxite residue.
基金Project supported by the National Basic Research Program (973) of China (No. 2003CB515402), and the Science and Technology Council of Zhejiang Province (No. 2005C23G2010166), China
文摘Objective: Some animal models apply morphine in the drinking water to generate addiction, but related reports are not free of conflicting results. Accordingly, this study aimed to figure out if chronic consumption of morphine in the drinking water can induce morphine addiction in Wistar rats. Methods: For 3 weeks, the animals received a daily morphine dose of 35 mg/kg by offering a calculated volume of sugar water (5% sucrose) with morphine (0. l mg/ml) to each rat; animals receiving just sugar water served as controls. Immediately after the treatment phase, the tail immersion test was used to check for morphine tolerance, and all animals were then kept on tap water for one week (withdrawal phase). Afterwards, all rats were allowed to choose their drinking source by offering two bottles, containing sugar water without and with morphine, simultaneously for two days (preference phase). Results: While the chronic consumption of morphine led to a reduction in body weight and to morphine tolerance, the morphine-treated Wistar rats did not show any preference for the opiate-containing sugar water. Conclusion: Body weight loss and tolerance do not reveal a condition of drug craving, and current animal models should be re-evaluated regarding their potential to establish morphine addicted animals.
基金the Baehrecke laboratory for helpful discussions and comments on this manuscript. Work on this subject has been supported by NR
文摘Programmed cell death plays an important role in maintaining homeostasis during animal development, and has been conserved in animals as different as nematodes and humans. Recent studies of Drosophila have provided valuable information toward our understanding of genetic regulation of death. Different signals trigger the novel death regulators rpr, hid, and grim, that utilize the evolutionarily conserved iap and ark genes to modulate caspase function. Subsequent removal of dying cells also appears to be accomplished by conserved mechanisms. The similarity between Drosophila and human in cell death signaling pathways illustrate the promise of fruit mes as a model system to elucidate the mechanisms underlying regulation of programmed cell death.
基金Project(6187031976)supported by the National Natural Science Foundation of China
文摘Self-diffraction appears when the strong laser goes through two-dimensional material suspension,and this spatial self-phase modulation(SPPM)phenomenon can be used to measure nonlinear optical parameters and achieve optical switch.At present,the mechanism of SPPM is still ambiguous.The debate mainly focuses on whether the phenomenon is caused by the nonlinear refractive index of the two-dimensional material or the thermal effect of the laser.The lack of theory limits the dimension of the phase modulation to the radius of the diffraction ring and the vertical imbalance.Therefore,it is urgent to establish a unified and universal SSPM theoretical system of two-dimensional material.
文摘A novel algorithm based on Radon-Ambiguity Transform (RAT) and Adaptive Signal Decomposition (ASD) is presented for the detection and parameter estimation of multicompo-nent Linear Frequency Modulated (LFM) signals. The key problem lies in the chirplet estimation. Genetic algorithm is employed to search for the optimization parameter of chirplet. High estimation accuracy can be obtained even at low Signal-to-Noisc Ratio(SNR). Finally simulation results are provided to demonstrate the performance of the proposed algorithm.
文摘The performances of nonlinear WDM systems with different duty cycle are compared by means of numerical simulation.The numerical results show that the optical pulse with duty cycle of 0.5 is superior to the conventional NRZ modulation scheme.The conclusion is different from that of some references.The reason is that inter symbol interference is not included in some references.In fact,inter symbol interference plays an important role in nonlinear WDM system.Although the larger the duty cycle is ,the stronger the effect of the cross-phase modulation and self-phase modulation on nonlinear WDM is,however,the larger the duty cycle is,the stronger the inter symbol interference is.
文摘A real-time auto-focusing system with auto-collimation method is introduced, which is used in auto-detecting the focus of the space camera with long focus. Auto-focusing is the key technique to ensure high quality in space imaging. It can measure and compensate the defocus caused by the change of temperature and air pressure etc. in space. To solve the problem of auto-focusing with auto-collimation method of the camera whose axis is perpendicular to the ground, it is designed that two small caliber pentagonal prisms are placed in the area of aperture suitable to the camera’s relative aperture based on the theory of auto-focusing with auto-collimation, which can replace the big caliber plane reflector used in other cameras. Using the characteristic of pentagonal prism refracting light vertically, the target slit is imaged in CCD through the two-separated lens. It transforms the detecting of the axial defocusing quantity to the landscape orientation measurement of the faculae’s position in the direction of CCD pixels. The defocusing quantity is obtained by measuring the opposite position of the two faculae on the CCD. The Centroid method is adopted to measure the position of the auto-collimation faculae. The arithmetic error is analyzed especially, and the causation is given. Experiments show that this real-time auto-focusing system using centroid method is reliable and the focusing precision can reach ±0.01 mm.
文摘This paper focuses on the design of the cross layer between the video application layer and the MIMO physical layer. MIMO physical layer research has promised an enormous increase in the capacity of wireless communication systems. Also MIMO wireless systems operate under fading conditions where the channel faces arbitrary fluctuations. Since the wireless channel changes over each coherence period, the capacity of the wireless channel, given the power constraints, changes. Hence to make efficient use of the available capacity one needs to adapt the video bit rate. However it is impossible to adapt at the application layer as changing the parameters of the video takes more time than the coherence period of the channel. In this paper we address this problem through a novel solution and also investigate its performance through a simulation study.
基金Project( 60425310) supported by the National Science Fund for Distinguished Young Scholars of ChinaProject(05JJ40118) supported by the Natural Science Foundation of Hunan Province, China
文摘The fact that outburst traffic in industrial Ethemet was focused on that would bring self-similar phenomenon leading to the delay increase of the cyclical data, and a hybrid priority queue schedule model was proposed in which the outburst data was given the highest priority. Some properties of the self-similar outburst data were proved by network calculus, and its service curve scheduled by the switch was gained. And then the performance of the scheduling algorithm was obtained. The simulation results are close to those calculated by using network calculus model. Some results are of actual significance to the construction of switched industrial Ethernet.
文摘For a permanent magnet synchronous motor(PMSM)model predictive current control(MPCC)system,when the speed loop adopts proportional-integral(PI)control,speed regulation is easily affected by motor parameters,resulting in the inability to balance the system robustness and dynamic performance.A PMSM optimal control strategy combining linear active disturbance rejection control(LADRC)and two-vector MPCC(TV-MPCC)is proposed.Firstly,a mathematical model of a PMSM is presented,and the PMSM TV-MPCC model is developed in the synchronous rotation coordinate system.Secondly,a first-order LADRC controller composed of a linear extended state observer and linear state error feedback is designed to reduce the complexity of parameter tuning while linearly simplifying the traditional active disturbance rejection control(ADRC)structure.Finally,the conventional PI speed regulator in the motor speed control system is replaced by the designed LADRC controller.The simulation results show that the speed control system using LADRC can effectively deal with the changes in motor parameters and has better robustness and dynamic performance than PI control and similar methods.The system has a fast motor speed response,small overshoot,strong anti-interference,and no steady-state error,and the total harmonic distortion is reduced.
文摘For more than two decades, immunologists have been using the so-called Th1/Th2 paradigm to explain most of the phenomena related to adaptive immunity. The Thl/Th2 paradigm implied the existence of two different, mutu- ally regulated, CD4+ T helper subsets: Thl cells, driving cell-mediated immune responses involved in tissue damage and fighting infection against intracellular parasites; and Th2 cells that mediate IgE production and are particu- larly involved in eosinophilic inflammation, allergy and clearance of helminthic infections. A third member of the T helper set, IL-17-producing CD4+ T cells, now called Th17 cells, was recently described as a distinct lineage that does not share developmental pathways with either Thl or Th2 cells. The Th17 subset has been linked to autoimmune disorders, being able to produce IL-17, IL-17F and IL-21 among other inflammatory cytokines. Interestingly, it has been reported that there is not only a cross-regulation among Thl, Th2 and Th17 effector cells but there is also a di- chotomy in the generation of Th17 and T regulatory cells. Therefore, Treg and Th17 effector cells arise in a mutually exclusive fashion, depending on whether they are activated in the presence of TGF-β or TGF-β plus inflammatory cytokines such as IL-6. This review will address the discovery of the Th17 cells, and recent progress on their development and regulation.
文摘The authors have investigated the pH and ionic strength response of self-assembled layers formed by adsorption of amphiphilic weak polyelectrolytes. Using the SFA (Surface Forces Apparatus) the authors measured force-distance profiles of poly (isoprene)-poly (acrylic acid) block copolymers adsorbed on mica. Also by Atomic Force Microscopy the authors captured single polyelectrolyte molecule adsorbed on a surface. The effect of salt concentration (Cs) and pH upon the height of the brush layers was explored mainly by measuring the forces between two adsorbed polyelectrolyte brushes. At pH = 4 our results are in good agreement with the scaling prediction L0 ∝Cs-1/3 Changing the pH from 4 to 10 causes a remarkable swelling of the polymer layer, but only a weak dependence on salt concentration was detected at the higher pH. This can be attributed to the degree of dissociation, which depends on the local pH value. At low pH the polyelectrolyte chains have a low charge density, while on increasing the pH the degree of dissociation rises, and the increased charge density is followed by swelling of the adsorbed layer. The local concentration of ions in the brush is now greater than that of pH = 4 and approximately equivalent to 0.3 M. So the swelling is only weakly dependent on salt concentration in the range 0.01-1.0 M. The results demonstrate the tunable nature of such self-assembled polyelectroiyte brushes whose height and range of interactions, can be systematically controlled by adjusting the pH and ionic strength of the medium.
文摘The effects of exercise on decision-making performance have been studied using a wide variety of cognitive tasks and exercise interventions. Although the current literature supports a beneficial influence of acute exercise on cognitive performance, the mechanisms underlying this phenomenon have not yet been elucidated. We review studies that used single-pulse transcranial magnetic stimulation (TMS) to probe the excitability of motor structures during whole-body exercise and present a framework to account for the facilitating effects of acute exercise on motor processes. Recent results suggest that, even in the absence of fatigue, the increase in corticospinal excitability classically reported during submaximal and exhausting exercises may be accompanied by a reduction in intracortical inhibition. We propose that reduced intracortical inhibition elicits an adaptive central mechanism that counteracts the progressive reduction in muscle responsiveness caused by peripheral fatigue. Such a reduction would render the motor cortex more sensitive to upstream influences, thus causing increased corticospinal excitability. Furthermore, reduction of intracortical inhibition may account for the more efficient descending drive and for the improvement of reaction time performance during exercise. The adaptive modulation in intracortical inhibition could be implemented through a general increase in reticular activation that would further account for enhanced sensory sensitivity.
基金Work supported by the Lancaster University,UK and Jiangsu Provincial Laboratory of Advanced Robotics,SooChow University,ChinaProject(BK2009509) supported by the Natural Science Foundation of Jiangsu Province,China+1 种基金Project(K5117827) supported by the Scientific Research Foundation for the Returned Scholars,Ministry of Education of ChinaProject(Q3117918) supported by the Scientific Research Foundation for Young Teachers of Soochow University,China
文摘Various control systems for a robotic excavator named LUCIE (Lancaster University Computerized and Intelligent Excavator),were investigated. The excavator is being developed to dig trenches autonomously. One stumbling block is the achievement of adequate,accurate,quick and smooth movement under automatic control. Here,both classical and modern approaches are considered,including proportional-integral-derivative (PID) control tuned by conventional Zigler-Nichols rules,linear proportional-integral-plus (PIP) control,and a novel nonlinear PIP controller based on a state-dependent parameter (SDP) model structure,in which the parameters are functionally dependent on other variables in the system. Implementation results for the excavator joint arms control demonstrate that SDP-PIP controller provides the improved performance with fast,smooth and accurate response in comparison with both PID and linearized PIP control.