The influence of the family of origin is often described in the aetiology of different psychiatric disorders. The majority of papers concerning the families of autistic children concentrate on the quality of their liv...The influence of the family of origin is often described in the aetiology of different psychiatric disorders. The majority of papers concerning the families of autistic children concentrate on the quality of their lives. The aim of our study was to compare the experiences from the family of origin of mothers of children with Autistic Spectrum Disorders （ASD） and from mothers of healthy children. In our study a Family of Origin Scale （FOS） was used. This scale consists of l0 constructs： clarity of expression, responsibility, respect for others, openness to others, acceptance of separation/loss, range of feelings, mood and tone, conflict resolution, empathy and trust. It was a pilot study. The examined group consisted of 9 mothers of children with ASD, the control group-7 mothers of healthy children. We found that both groups differed in a statistically significant way as for the construct called responsibility. Our research was a pilot study and it required further investigations.展开更多
Motor impairments in autism spectrum disorders(ASD) have received far less research attention than core social- communication and cognitive features. Yet, behavioral, neurophysiological, neuroimaging and histopatholog...Motor impairments in autism spectrum disorders(ASD) have received far less research attention than core social- communication and cognitive features. Yet, behavioral, neurophysiological, neuroimaging and histopathological studies have documented abnormal motor system development in the majority of individuals with ASD suggesting that these deficits may be primary to the disorder. There are several unique advantages to studying motor development in ASD. First, the neurophysiological substrates of motor skills have been well-characterized via animal and human lesion studies. Second, many of the single-gene disorders associated with ASD also are characterized by motor dysfunctions. Third, recent evidence suggests that the onset of motor dysfunctions may precede the emergence of social and communication deficits during the first year of life in ASD. Motor deficits documented in ASD indicate disruptions throughout the neuroaxis affecting cortex, striatum, the cerebellum and brainstem. Questions remain regarding the timing and development of motor system alterations in ASD, their association with defining clinical features, and their potential for parsing heterogeneity in ASD. Pursuing these questions through neurobiologically informed translational research holds great promise for identifying gene-brain pathways associated with ASD.展开更多
文摘The influence of the family of origin is often described in the aetiology of different psychiatric disorders. The majority of papers concerning the families of autistic children concentrate on the quality of their lives. The aim of our study was to compare the experiences from the family of origin of mothers of children with Autistic Spectrum Disorders （ASD） and from mothers of healthy children. In our study a Family of Origin Scale （FOS） was used. This scale consists of l0 constructs： clarity of expression, responsibility, respect for others, openness to others, acceptance of separation/loss, range of feelings, mood and tone, conflict resolution, empathy and trust. It was a pilot study. The examined group consisted of 9 mothers of children with ASD, the control group-7 mothers of healthy children. We found that both groups differed in a statistically significant way as for the construct called responsibility. Our research was a pilot study and it required further investigations.
基金supported by the National Institute of Child Health and Human Development Collaborative Program of Excellence in Autism(Grant No.HD35469)the National Institute of Mental Health Autism Center of Excellence(Grant No.P50HD055751)the National Alliance for Autism Research,and Autism Speaks Grant 4853
文摘Motor impairments in autism spectrum disorders(ASD) have received far less research attention than core social- communication and cognitive features. Yet, behavioral, neurophysiological, neuroimaging and histopathological studies have documented abnormal motor system development in the majority of individuals with ASD suggesting that these deficits may be primary to the disorder. There are several unique advantages to studying motor development in ASD. First, the neurophysiological substrates of motor skills have been well-characterized via animal and human lesion studies. Second, many of the single-gene disorders associated with ASD also are characterized by motor dysfunctions. Third, recent evidence suggests that the onset of motor dysfunctions may precede the emergence of social and communication deficits during the first year of life in ASD. Motor deficits documented in ASD indicate disruptions throughout the neuroaxis affecting cortex, striatum, the cerebellum and brainstem. Questions remain regarding the timing and development of motor system alterations in ASD, their association with defining clinical features, and their potential for parsing heterogeneity in ASD. Pursuing these questions through neurobiologically informed translational research holds great promise for identifying gene-brain pathways associated with ASD.
