臭氧化溶液治疗肛周皮肤糜烂的效果观察

目的探讨臭氧化溶液治疗肛周皮肤糜烂的临床效果。方法对本院62例肛周皮肤糜烂患者应用臭氧化溶液进行治疗，治疗3～6d评估疗效。结果本组62例患者肛周皮肤糜烂痊愈52例，有效9例，无效1例，总有效率98．4％。结论臭氧化溶液治疗肛周皮肤糜烂临床疗效好，操作简单。

臭氧化0.9%氯化钠溶液治疗兔VX2肿瘤模型有效性和安全性研究

目的探讨臭氧化0.9%氯化钠溶液治疗VX2肿瘤的有效性和安全性。方法构建新西兰大白兔VX2肿瘤模型72只,随机分为4组(各18只)。超声导引下分别予瘤内单次注射0.9%氯化钠溶液(A组)、单次注射臭氧化0.9%氯化钠溶液(B组)、2次注射臭氧化0.9%氯化钠溶液(1次/d,连续2 d,C组),3次注射臭氧化0.9%氯化钠溶液(1次/d,连续3 d,D组),剂量均为2倍肿瘤体积。治疗前、治疗后每间隔4 d检测肿瘤大小及从心脏采血3 mL。计算肿瘤生长率,检测血常规、肝肾功能变化。结果各组肿瘤体积于各时点均不同程度增大,但B、C、D组肿瘤生长率均明显低于A组,差异均有统计学意义(P<0.05),且B组最低(效果最佳)。各组各时点间血常规及肝肾功能变化比较,差异均无统计学意义(P>0.05)。结论臭氧化0.9%氯化钠溶液瘤内注射可安全有效地抑制肿瘤生长。

Ozonation of Sulfur Dioxide in Sulphuric Acid Solution

In this study, the oxidation rates of sulfur dioxide （SO2） in sulphuric acid solution by ozone and oxygen were compared, and the oxidation mechanism of ozone on SO2 was investigated. The results showed that the oxidation-reduction potential of the acidic solution was enhanced, the transformation rate of sulfuric acid to sulphuric acid was increased and the absorption driving force was improved in the presence of ozone. By comparing the amount of sulfate ions measured in the experiments and the theoretical amount of sulfate ions calculated from the amount of ozone consumed in the reaction, it can be confirmed that oxygen free radicals from dissociation of ozone are reactive as an efficient oxidant and oxygen from ozone generator participates in the reaction with SO2. 0.602 mol of effective oxygen was introduced into the reaction by one mole of ozone in 10.15 rain at sulphuric acid concentration of 3% （by mass）, SO2 concentration of 1.33% （by volume） and oxygen flow rate of 1.5 L.min^-1 from ozone generator.