先天性脊柱裂致神经营养性骨关节病2例报告

先天性脊柱裂引起足踝关节病变。查阅近几年来有关放射学杂志,未见类似报告。现就其诊治过程报告如下。[例1]患者男,34岁。右足感染久治不愈2年。曾诊为跟骨骨髓炎,行跟骨病灶清除术,术后伤口不愈,分泌物多次细菌培养无细菌生长。既往无外伤史及其它病史。查体:右足跟缺失。

道教存想致神的思维方式与《聊斋志异》的幻想故事

文学与宗教的关系密切,志怪小说《聊斋志异》大多数幻想故事的构思方式就深受道教存想致神思维方式的影响。男主人公在摄想凝思之中遭遇异类,实现了在现实生活中不能实现的人生愿望,作者在杜撰这些幻想故事的过程中也达到了自我疗伤的创作目的。

高血糖易致神经病变

王大爷这两个月总是吃饭时满头大汗,排便也不太正常,一会儿便秘、一会儿腹泻,吃了不少药都不见好转,家人提醒他赶快到医院看看。于是王大爷来到了家附近的医院,内分泌科医生详细询问病史并仔细给他体检后,告诉他,这是高血糖引起的糖尿病自主神经病变。

出征时刻——致神九飞行乘组

骄阳以火大漠敞开炽热的胸膛人潮欢涌泪水模糊了搜寻的目光旌旗猎猎战鼓擂响出征太空的勇士已整好行装勇敢去飞吧我的战友追求的梦想就在前方飞天飞天再次用卓越铸就辉煌

A Hybrid Compensation Scheme for the Input Rate-Dependent Hysteresis of the Piezoelectric Ceramic Actuators

A hybrid compensation scheme for piezoelectric ceramic actuators(PEAs)is proposed.In the hybrid compensation scheme,the input rate-dependent hysteresis characteristics of the PEAs are compensated.The feedforward controller is a novel input rate-dependent neural network hysteresis inverse model,while the feedback controller is a proportion integration differentiation(PID)controller.In the proposed inverse model,an input ratedependent auxiliary inverse operator(RAIO)and output of the hysteresis construct the expanded input space(EIS)of the inverse model which transforms the hysteresis inverse with multi-valued mapping into single-valued mapping,and the wiping-out,rate-dependent and continuous properties of the RAIO are analyzed in theories.Based on the EIS method,a hysteresis neural network inverse model,namely the dynamic back propagation neural network(DBPNN)model,is established.Moreover,a hybrid compensation scheme for the PEAs is designed to compensate for the hysteresis.Finally,the proposed method,the conventional PID controller and the hybrid controller with the modified input rate-dependent Prandtl-Ishlinskii(MRPI)model are all applied in the experimental platform.Experimental results show that the proposed method has obvious superiorities in the performance of the system.

针刺方法杀死昆虫制作标本

在小学自然课本中,有不少有关昆虫知识的教学内容。制作昆虫标本,既能使学生学好昆虫知识又能培养学生动手能力。制作昆虫标本的传统方法是,先要用毒瓶或毒药把昆虫毒死,然后展翅或定型。但使用毒瓶或毒药,对小年龄的学生来说不很理想,一不注意,就会污染。

DOWN－REGULATION OF C－MYC ONCOGENE DURING NGF－INDUCED DIFFERENTIATION OF NEUROBLASTOMA CELL LINES

There may be a close relationship between myc oncogenes and carcinogenesis of human neuroblastoma. In previous studies, we were able to induce differentiation of certain neuroblastoma cell lines with NGF. In order to study gene regulation during differentiation, N-myc and c-myc cDNA probe were hybridized with RNA extracted from different cell lines before and after NGF treatment. It was found that cell lines which expressed N-myc did not express c-myc while those with c-myc did not express N-myc except for SHEP cell line which had neither c-myc nor N-myc expression. In NGF-induced differentiated neuroblastoma cells, c-myc oncogene was down-regulated in comparison with the control samples. The time course of c-myc down-regulation was concomitant with the appearance of morphological differentiation. In situ hybridization also showed remarkable reduction of c-myc oncogene expression in NGF-induced differentiated cells as compared with the untreated control cells. These results indicate that down-regulation of c-myc oncogene may be a key event during NGF-induced differentiation and overexpression of c-myc oncogene may, at least partially, be responsible for the genesis of neuroblastoma.

Electroluminescence Device to Implement the Clipped Hopfield Neural Network

The method,which used an electroluminescent device to implement the clipped Hopfield neural network,is presented in detail.The electroluminescence devices are used to represent the neurons and the photodetectors are used to represent the connection matrix.The characteristics of the electroluminescence device and the photodetector are tested.And the characteristics of this system is discussed briefly.

THE RELATIONSHIP BETWEEN EXPRESSIONS OF N-myc AND c-myc ONCOGENES IN NEUROBLASTOMA:AN IN SITU HYBRIDIZATION AND IMMUNOCYTOCHEMICAL STUDY

ＩＮＴＲＯＤＵＣＴＩＯＮＮｅｕｒｏｂｌａｓｔｏｍａｏｒｉｇｉｎａｔｅｓｆｒｏｍｔｈｅｓｙｍｐａｔｈｏａｄ－ｒｅｎａｌｌｉｎｅａｇｅｏｆｔｈｅｎｅｕｒａｌｃｒｅｓｔａｎｄｉｔｉｓｔｈｅｍｏｓｔｃｏｍｍｏｎｅｘｔｒａ－ｃｒａｎｉａｌｔｕｍｏｒｏｆｃｈｉｌ...

Finding Consistency in Rousseau

Several of Rousseau＇s critics begin with the presupposition that his writings are inconsistent or incoherent ann proceed to locate the ＂essence＂ of his philosophy in some of his writings while excluding others. Ernst Cassirer is among the few philosophers who have attempted to defend Rousseau＇s claim to consistency. Despite its broad influence, Cassirer＇s interpretation has remained largely unchallenged. The aim of this paper is twofold. Firstly, it aims to show that Cassirer＇s interpretation undermines （1） the important role Rousseau assigns to pity in both the state of nature and civil society and （2） the significant role the general will plays in his political theory. Secondly, it proposes an alternative interpretation that succeeds in uniting Rousseau＇s opus.

Effects of Coupling Distance on Synchronization and Coherence in Chaotic Neural Networks

Effects of coupling distance on synchronization and coherence of chaotic neurons in complex networks arenumerically investigated.We find that it is not beneficial to neurons synchronization if confining the coupling distanceof random edges to a limit d_(max),but help to improve their coherence.Moreover,there is an optimal value of d_(max) atwhich the coherence is maximum.

Assessment of compliance-relevant indispensable knowledge to cope with epilepsy in epileptic patients in Xi'an

Objective: To investigate the knowledge level related to compliance in patients with epilepsy. Methods: Eighty-seven patients with epilepsy were tested in the city of Xi’an with a knowledge questionnaire containing 21 questions related to compliance. Results: Over 39.5% of patients did not know that epilepsy is the result of abnormal firing of neurons, while 29.9% were uncertain or did not realize that epilepsy attacks can bring up accidents such as traffic accidents, drowning and trauma. A total of 36.6% of responders thought that the best therapy for epilepsy could be found in Traditional Chinese Medicine. As many as 36.8% of tested patients were uncertain or did not know that frequent epilepsy attacks can affect their intelligence. Up to 36% were unaware of the possible consequence of sudden withdrawal of anti-epileptic drugs (AED). Among responders, 39.1% did not know the right treatment method of epilepsy. That AED can control seizure attacks were doubted in 57.5% of epileptic patients. Furthermore, 32.2% did not know whether the disease could be cured. Conclusion: In this group of epileptic patients, generally they do not have enough indispensable knowledge to cope with epilepsy. They urgently need for proper health education besides effective AED to control seizure attacks and improve their quality of life.

Clinical efficacy of acupoint injection for chemotherapy-induced peripheral neuropathy of patients with breast cancer

Objective To observe the clinical efficacy of acupoint injection for chemotherapy-induced peripheral neuropathy （ClPN）. Methods Ninety ClPN patients with breast cancer conforming to inclusive criteria were randomly divided into an acupuncture group （group A）, a mecobalamin group （group B） and an acupoint injection group （group C） according to random number table, with 30 cases in each group. In group A, acupuncture was conducted at bilateral Q0chi （I~ LI 11）, H6g6 （~ LI 4）, Z0s^nlT （~__~ ST 36）, S^nyinji^o （^-- ~ SP 6） and Xu^h~i （J~ SP 10）; in group B, intramuscular injection with I mL of mecobalamin injection was conducted; and in group C, acupoint selection was the same as group A, and 0.1 mL of mecobalamin injection was injected into each acupoint, respectively. The treatment was conducted once every three days in each group, and the changes of clinical efficacy, nerve electrophysiology and hemorrheology indicators after treatment for 10 times were observed. Result The total effective rate of group C was 93.1% （27/29）, which was higher than 78.6% （22/28） in group A and 83.3% （25/30） in group B, and the differences among three groups were statistically significant （all P〈0.01）; conduction velocity of lesion nerves was improved in group B and group C, the improvement in group C was obviously superior to the other two groups （all P〈0.01）, hemorrheology indicator was improved in group A and group C （both P〈0.05）. Conclusion The efficacy of acupoint injection with mecobalamin for breast cancer CIPN was significant, which can not only improve the nerve conduction velocity, but also improve the hemorrheology indicator.

Effect of electroacupuncture on chemotherapy-induced peripheral neuropathy in patients with malignant tumor：a single-blinded,randomized controlled trial

OBJECTIVE:To evaluate the effect of electroacupuncture on chemotherapy-induced peripheral neuropathy(CIPN), quality of life and immune status of patients with malignant tumors.METHODS:From Jan, 2013 to May, 2014, 37 patients with malignant tumors were included in this prospective single-blinded study, and randomized to receive either electroacupuncture or acupuncture treatment on basis of chemotherapy.The chemotherapy was continued for 2 courses as previous before the treatments, with 21 days as a course of treatment.Patients received acupuncture and electroacupuncture once per day starting at the day before chemotherapy for consecutive 7 days followed by 14 days off, with 21 days as a course of treatment, and continued for two courses of treatment.Then CIPN, traditional Chinese clinical symptoms,quality of life and immune status were all evaluated for each patient prior treatment and after two courses of treatment.RESULTS:The gender, age, cancer species as well as incidence(83.3% vs 84.2%) and grades of CIPN before treatments were all similar in patients receiving acupuncture or electroacupuncture(all P >0.05).After treatments, most patients with peripheral neuropathy were cured by two courses of electroacupuncture(84.2% vs 21.1%), whereas the other group of patients had similar incidences of peripheral neuropathy compared with prior-acupuncture(83.3% vs 72.2%).Besides, patients receiving electroacupuncture had lower incidence of peripheral neuropathy than those receiving acupuncture treatment(χ~2= 9.745, P = 0.002).The grades of peripheral neuropathy were significantly different in the two groups post-treatment(χ~2= 13.983, P =0.007).The total effective rates for traditional Chinese clinical symptoms were 16.7% and 84.2% in acupuncture and electroacupuncture groups, respectively(Z =-4.239, P < 0.001).The electroacupuncture treatment provided a more satisfactory life for patients compared with acupuncture(Z =-4.76, P < 0.001).Both electroacupuncture and acupuncture had no effects on immune function.CONCLUSION:Electroacupuncture could alleviate CIPN, and improve traditional Chinese clinical symptoms and quality of life, but did not affect immune function.

Penalized least squares estimation with weakly dependent data

In statistics and machine learning communities, the last fifteen years have witnessed a surge of high-dimensional models backed by penalized methods and other state-of-the-art variable selection techniques.The high-dimensional models we refer to differ from conventional models in that the number of all parameters p and number of significant parameters s are both allowed to grow with the sample size T. When the field-specific knowledge is preliminary and in view of recent and potential affluence of data from genetics, finance and on-line social networks, etc., such（s, T, p）-triply diverging models enjoy ultimate flexibility in terms of modeling, and they can be used as a data-guided first step of investigation. However, model selection consistency and other theoretical properties were addressed only for independent data, leaving time series largely uncovered. On a simple linear regression model endowed with a weakly dependent sequence, this paper applies a penalized least squares（PLS） approach. Under regularity conditions, we show sign consistency, derive finite sample bound with high probability for estimation error, and prove that PLS estimate is consistent in L_2 norm with rate （s log s/T）～1/2.