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浅谈良性脑瘤的保守治疗
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作者 金基春 姜勋 韩磊 《中国实用医药》 2016年第11期109-110,共2页
目的探讨良性脑瘤的保守治疗进展。方法回顾性分析30例良性脑瘤患者的临床资料。结果在影像学上保守治疗良性瘤有减小或未再发展的比例达11.5%。治疗头痛有效率为20.0%,癫痫60.0%,致残率和复发率均较低。结论保守疗法在理论上合理且疗... 目的探讨良性脑瘤的保守治疗进展。方法回顾性分析30例良性脑瘤患者的临床资料。结果在影像学上保守治疗良性瘤有减小或未再发展的比例达11.5%。治疗头痛有效率为20.0%,癫痫60.0%,致残率和复发率均较低。结论保守疗法在理论上合理且疗效上有临床价值。 展开更多
关键词 良性脑瘤 保守治疗
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Science Letters:Serum protein fingerprinting coupled with artificial neural network distinguishes glioma from healthy population or brain benign tumor 被引量:6
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作者 刘建 郑树 +2 位作者 余捷凯 张建民 陈喆 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2005年第1期4-10,共7页
To screen and evaluate protein biomarkers for the detection of gliomas (Astrocytoma grade Ⅰ-Ⅳ) from healthy individuals and gliomas from brain benign tumors by using surface enhanced laser desorption/ionization time... To screen and evaluate protein biomarkers for the detection of gliomas (Astrocytoma grade Ⅰ-Ⅳ) from healthy individuals and gliomas from brain benign tumors by using surface enhanced laser desorption/ionization time of flight mass spectrometry (SELDI-TOF-MS) coupled with an artificial neural network (ANN) algorithm. SELDI-TOF-MS protein fingerprinting of serum from 105 brain tumor patients and healthy individuals, included 28 patients with glioma (Astrocytoma Ⅰ-Ⅳ), 37 patients with brain benign tumor, and 40 age-matched healthy individuals. Two thirds of the total samples of every compared pair as training set were used to set up discriminating patterns, and one third of total samples of every compared pair as test set were used to cross-validate; simultaneously, discriminate-cluster analysis derived SPSS 10.0 software was used to compare Astrocytoma grade Ⅰ-Ⅱ with grade Ⅲ-Ⅳ ones. An accuracy of 95.7%, sensitivity of 88.9%, specificity of 100%, positive predictive value of 90% and negative predictive value of 100% were obtained in a blinded test set comparing gliomas patients with healthy individuals; an accuracy of 86.4%, sensitivity of 88.9%, specificity of 84.6%, positive predictive value of 90% and negative predictive value of 85.7% were obtained when patient's gliomas was compared with benign brain tumor. Total accuracy of 85.7%, accuracy of grade Ⅰ-Ⅱ Astrocytoma was 86.7%, accuracy ofⅢ-Ⅳ Astrocytoma was 84.6% were obtained when grade Ⅰ-Ⅱ Astrocytoma was compared with grade Ⅲ-Ⅳ ones (discriminant analysis). SELDI-TOF-MS combined with bioinformatics tools, could greatly facilitate the discovery of better biomarkers. The high sensitivity and specificity achieved by the use of selected biomarkers showed great potential application for the discrimination of gliomas patients from healthy individuals and glioma from brain benign tumors. 展开更多
关键词 ASTROCYTOMA Artificial Neural Network(ANN) SELDI-TOF-MS Protein fingerprint Diagnosis
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Choroid Plexus Papilloma of the Fourth Ventricle Developing Postoperative Intracranial and Rectal Hemorrhage Three Times: A Case Report
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作者 Heng-zhu ZHANG Lei SHE Lin YANG Xian ZHANG Lun DONG Xiao-dong WANG Lin-hai SHEN Jian LI 《Clinical oncology and cancer researeh》 CAS CSCD 2010年第1期60-63,共4页
Introduction Choroid plexus papilloma (CPP) is a relatively rare, slow-growing benign tumor (WHO level I). Recently, an adult patient with fourth ventricle choroid plexus papilloma received surgery via a suboc- ci... Introduction Choroid plexus papilloma (CPP) is a relatively rare, slow-growing benign tumor (WHO level I). Recently, an adult patient with fourth ventricle choroid plexus papilloma received surgery via a suboc- cipital midline approach in our hospital. It has been rare in clinical practice to see postoperative hemorrhage occurring in the same patient 3 times. The causes of the hemorrhage were analyzed based on literature regarding postoperative hemorrhage in choroid plexus papilloma and in intracranial tumors. The case involved in our study is described and detailed in the following. 展开更多
关键词 choroid plexus papilloma antineoplasticprotocols operative complications.
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