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良性前列腺增生诊断和治疗的百年历史 被引量:15
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作者 王忠 陈其 钱伟庆 《上海医学》 北大核心 2017年第7期411-414,共4页
良性前列腺增生(BPH)是导致下尿路症状(LUTS)影响老年男性健康的重要问题。超过50%的80岁左右男性有中度到重度的LUTS,导致其生活质量下降和需要药物或手术治疗。对于患者而言,理想的治疗方案是通过最小的创伤取得最长久的疗效... 良性前列腺增生(BPH)是导致下尿路症状(LUTS)影响老年男性健康的重要问题。超过50%的80岁左右男性有中度到重度的LUTS,导致其生活质量下降和需要药物或手术治疗。对于患者而言,理想的治疗方案是通过最小的创伤取得最长久的疗效,在过去的1个世纪里,泌尿外科医师朝着这一目标孜孜不倦地努力着。 展开更多
关键词 良性前列腺增生诊断 手术治疗 泌尿外科医师 男性健康 下尿路症状 LUTS 生活质量 治疗方案
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B超应用于胆囊良性病变诊断的价值探讨 被引量:3
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作者 潘东英 《当代医学》 2012年第36期44-44,共1页
目的探讨B超诊断胆囊良性病变的临床价值。方法回顾分析2011年1月~2012年3月东南大学医学院附属江阴医院257例胆囊良性病变患者的临床资料,总结良性病变的种类、B超影像学特点和诊断准确率。结果 257例胆囊良性病变中,急性胆囊炎114例... 目的探讨B超诊断胆囊良性病变的临床价值。方法回顾分析2011年1月~2012年3月东南大学医学院附属江阴医院257例胆囊良性病变患者的临床资料,总结良性病变的种类、B超影像学特点和诊断准确率。结果 257例胆囊良性病变中,急性胆囊炎114例,胆囊息肉43例,胆囊结石100例,胆囊结石合并胆囊炎急性发作49例。急性胆囊炎B超主要表现:胆囊增大、胆囊壁变厚、毛糙,部分可见散在片状、点状等回声;胆囊息肉B超主要表现:胆囊壁上可见不随体位改变而移动的局部强回声或等回声;胆囊结石B超主要表现:可随体位变化的圆形或椭圆形强光团和声影。B超诊断急性胆囊炎、胆囊息肉、胆囊结石的准确率分别为81.58%(93例)、90.70%(39例)和96.00%(96例)。结论 B超诊断胆囊良性病变具有较高的准确率,是首选的无创检查方法。 展开更多
关键词 B超 胆囊良性病变 诊断
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改良滚转试验对水平半规管良性阵发性位置性眩晕的诊断价值
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作者 肖本杰 毕涌 +1 位作者 郑天衡 庄建华 《医学临床研究》 CAS 2021年第8期1176-1178,共3页
【目的】通过对经典滚转试验(roll test)的改良,探讨其对水平半规管良性阵发性位置性眩晕的诊断价值。【方法】收集2017年10月1日至2019年12月31日在同济大学附属上海市第四人民医院神经内科头晕门诊就诊的57例水平半规管良性阵发性位... 【目的】通过对经典滚转试验(roll test)的改良,探讨其对水平半规管良性阵发性位置性眩晕的诊断价值。【方法】收集2017年10月1日至2019年12月31日在同济大学附属上海市第四人民医院神经内科头晕门诊就诊的57例水平半规管良性阵发性位置性眩晕(Horizontal Canal Benign Paroxysmal Positional Vertigo,HC-BP-PV)患者临床资料,同时予经典的roll test和改良的roll test(头位滚转从90°改良成180°),比较两者对眼震持续时间以及HC-BPPV患侧确诊的影响。【结果】患侧与健侧眼震持续时间及持续时间差的比较,无论是游离性耳石、还是黏附性耳石,改良roll test与经典roll test的差异均有统计学意义(P<0.05);对于游离性耳石患侧的确诊率,改良roll test与经典roll test差异无统计学意义(P=0.242>0.05),对于黏附性耳石的确诊率,两者差异有统计学意义(P<0.05)。【结论】改良roll test相对经典roll test使两侧眼震差异更明显,有助更好判断HC-EP-PV的患侧,有效提高黏附性耳石HC-BPPV患侧的确诊率,但对游离性耳石HC-EPPV患侧的确诊率影响不大。 展开更多
关键词 良性阵发性位置性眩晕/诊断 诊断 鉴别
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膀胱出口梗阻的诊断和治疗概况 被引量:3
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作者 陈武平 《右江民族医学院学报》 2005年第5期735-736,共2页
关键词 膀胱颈梗阻 泌尿生殖系统疾病 良性前列腺增生诊断 治疗
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甲状腺疾病b超诊断的可行性研究 被引量:1
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作者 宋海超 《益寿宝典》 2020年第1期99-99,共1页
分析B超应用于甲状腺疾病检查中的临床意义。方法:选取2019年4月到2019年12月期间的120例甲状腺疾病患者进行回顾性研究,并分析甲状腺的B超检查的诊断结果。结果:甲状腺B超检查结果为良性病变100例,甲状腺恶性病变20例。甲状腺病理检查... 分析B超应用于甲状腺疾病检查中的临床意义。方法:选取2019年4月到2019年12月期间的120例甲状腺疾病患者进行回顾性研究,并分析甲状腺的B超检查的诊断结果。结果:甲状腺B超检查结果为良性病变100例,甲状腺恶性病变20例。甲状腺病理检查结果为良性病变103例,恶性病变17例。甲状腺疾病诊断的“金标准”为病理检查,甲状腺B超检查漏诊2例,其余5例为误诊。根据上述数据,我们可以计算出甲状腺B超诊断的敏感性为88.2%(15/17),特异度为95.1%(98/103),准确性为94.1%(113/120),阳性率为75%(15/20),阴性率为98%(98/100)。结论:应用B超诊断甲状腺疾病准确率高,临床应用上有很大的价值,值得推广使用。 展开更多
关键词 甲状腺疾病 B超 良性诊断 恶性诊断 临床应用
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超声造影技术在肾脏实质良、恶性病灶诊断中的应用
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作者 张卫平 周爱云 +3 位作者 陈莉 邓林云 喻沁 周美珍 《南昌大学学报(医学版)》 CAS 2010年第8期73-74,共2页
目的探讨超声造影技术在肾脏实质良、恶性病灶诊断中的应用。方法 10例经彩色多普勒超声诊断为肾脏占位患者,用声诺维(Sonovue)对患侧肾脏进行超声造影,实时动态记录整个超声造影过程,观察注射造影剂前后的肾脏及局部病灶的超声造影声... 目的探讨超声造影技术在肾脏实质良、恶性病灶诊断中的应用。方法 10例经彩色多普勒超声诊断为肾脏占位患者,用声诺维(Sonovue)对患侧肾脏进行超声造影,实时动态记录整个超声造影过程,观察注射造影剂前后的肾脏及局部病灶的超声造影声像图特征表现。结果 10例肾脏病灶中,7例肾脏恶性病灶表现为快进快出、快进慢出等不同造影模式,但均呈高增强;2例错构瘤表现为慢进慢出,周边向中央增强,呈现为等增强,或低增强;1例肾柱肥大着在造影过程中均无明显的包块,并见其两侧的相对粗大的血管显影。结论应用Sonovue超声造影能显著增强肾脏实质占位性病灶的血流信号,有助于准确评价病灶内的血供状况,对肾脏实质占位性病灶的良恶性鉴别诊断有重要的意义。 展开更多
关键词 超声造影 肾脏病灶 鉴别诊断 良性 恶性
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超声造影在乳腺良恶性肿瘤鉴别诊断中的价值分析 被引量:1
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作者 周策勋 董娇楼 赵亚丽 《影像研究与医学应用》 2020年第4期51-52,共2页
目的:探讨对乳腺良恶性肿瘤通过超声造影实施鉴别诊断的临床价值。方法:将我院2016年08月-2019年09月收治的80例乳腺肿瘤患者作为研究对象;经病理诊断,良性、恶性肿瘤分别为45例以及35例;针对所有患者于临床分别展开超声造影检查以及二... 目的:探讨对乳腺良恶性肿瘤通过超声造影实施鉴别诊断的临床价值。方法:将我院2016年08月-2019年09月收治的80例乳腺肿瘤患者作为研究对象;经病理诊断,良性、恶性肿瘤分别为45例以及35例;针对所有患者于临床分别展开超声造影检查以及二维超声检查操作,对应设为超声造影组以及二维超声组;就获得乳腺良恶性鉴别诊断结果进行观察对比。结果:经超声造影诊断后,敏感度为33/35=94.29%;特异度为35/45=77.78%;准确度为(33+35)/80=85.00%;经二维超声诊断后,敏感度为13/35=37.14%;特异度为26/45=57.78%;准确度为(13+26)/80=48.75%;最终发现超声造影组敏感度、特异度以及准确度均高于二维超声组明显(P<0.05)。结论:超声造影检测方法的合理采用,使得乳腺疾病患者诊断效果获得显著提升,尤其对于疾病良性、恶性可以充分明确,最终为良恶性乳腺肿瘤患者对应治疗方案的创建提供依据。 展开更多
关键词 超声造影 乳腺良恶性肿瘤 良性诊断检出率 恶性诊断检出率
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VTQ技术对乳腺肿块良恶性的准确性及诊断价值 被引量:4
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作者 翁沛华 《中国医药科学》 2020年第4期247-250,共4页
目的探讨VTQ技术对乳腺肿块良恶性的准确性及诊断价值。方法选取2017年1月~2019年1月本院收治的乳腺肿瘤患者84例,共存在乳腺实性肿块99个,分别采用声触诊组织量化(VTQ)以及声触诊组织成像(VTI)联合Adobe Photoshop进行良、恶性诊断,分... 目的探讨VTQ技术对乳腺肿块良恶性的准确性及诊断价值。方法选取2017年1月~2019年1月本院收治的乳腺肿瘤患者84例,共存在乳腺实性肿块99个,分别采用声触诊组织量化(VTQ)以及声触诊组织成像(VTI)联合Adobe Photoshop进行良、恶性诊断,分析其诊断价值。结果恶行乳腺肿块中央部位VS值明显高于良性乳腺肿块(P <0.05);恶性乳腺肿块灰度平均值明显低于良性乳腺肿块(P<0.05);VTQ诊断良性率、恶性率与病理诊断结果无统计学意义(P> 0.05);VTI诊断良性率、恶性率与病理诊断结果无统计学意义(P> 0.05);VTQ诊断灵敏度、特异度以及准确度明显高于VTI检测;VTQ诊断与VTI诊断一致率为77.8%。结论在对乳腺肿块进行良恶性诊断时,VTQ诊断具有更高的灵敏度、特异度以及准确度,可以良好区分乳腺肿块的良、恶性,为乳腺癌诊断提供技术支持。 展开更多
关键词 VTQ VTI 乳腺肿块 良性恶性诊断 准确度
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意义未明单克隆免疫球蛋白病及多发性骨髓瘤患者微RNA-221和微RNA-222的表达 被引量:5
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作者 杨肃文 王伟 +2 位作者 金红 钟玉虹 谢鑫友 《浙江大学学报(医学版)》 CAS CSCD 北大核心 2016年第4期371-378,共8页
目的:探讨意义未明单克隆免疫球蛋白病( MGUS )、多发性骨髓瘤(MM)患者血清和浆细胞中微RNA-221(miR-221)和微RNA-222(miR-222)的表达水平及其作为MGUS、MM诊断和预测预后生物学指标的可能性。方法:收集2013年1月至2015年12... 目的:探讨意义未明单克隆免疫球蛋白病( MGUS )、多发性骨髓瘤(MM)患者血清和浆细胞中微RNA-221(miR-221)和微RNA-222(miR-222)的表达水平及其作为MGUS、MM诊断和预测预后生物学指标的可能性。方法:收集2013年1月至2015年12月浙江大学医学院附属邵逸夫医院及浙江省立同德医院14例初诊MGUS患者、81例初诊及复发MM患者和10名健康对照者的血清及骨髓标本,其中骨髓标本用CD138磁珠分选浆细胞。用实时定量PCR检测血清和浆细胞中miR-221/222的表达量。采用Δct表示miR-221/222的相对表达量并比较组间差异。比较缓解组和难治组MM患者治疗前后血清miR-221表达水平的变化,并分析其与血清β2微球蛋白的相关性。结果:MGUS 患者和 MM 患者血清miR-221/222的表达量均较对照组高(均P<0.01),而浆细胞miR-221/222的表达量均较对照组低( P<0.05或<0.01);MGUS与MM患者miR-221和miR-222表达量的差异在血清中或在浆细胞中均无统计学意义(均P>0.05)。 miR-221和miR-222表达量在血清与浆细胞之间无相关性(r=0.024和-0.127,均P>0.05);而血清和浆细胞 miR-221与 miR-222表达量之间均具有相关性( r =0.534和0.552,均P<0.01)。受试者工作特征( ROC)曲线显示血清miR-221/222和浆细胞miR-221/222诊断MGUS、MM 的曲线下面积( AUC )分别为0.968和0.976、0.801和0.727。 MM患者不同M-蛋白类型之间血清miR-221的表达量差异无统计学意义(P>0.05)。复发患者血清miR-221的表达量高于初诊患者(P<0.01)。DS分期为Ⅲ期MM患者血清miR-221表达量高于MGUS及DS分期Ⅰ期和Ⅱ期MM患者(P<0.01)。缓解组治疗后血清miR-221表达量低于治疗前(U=51.5, P<0.01),而难治组治疗前后血清miR-221表达量差异无统计学意义(U=67.5, P>0.05)。 MM患者血清β2微球蛋白水平与血清miR-221的表达量呈正相关(r=0.524,P<0.01)。结论:检测患者血清、浆细胞miR-221/222表达量有助于MGUS的早期诊断,也有助于MM的诊断及疗效观察。 展开更多
关键词 多发性骨髓瘤/诊断 多发性骨髓瘤/病理学 单克隆丙种球蛋白病 良性/诊断 微RNAs/血液 预后
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应用SRM-Ⅳ进行速度阶梯试验的可行性分析 被引量:5
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作者 孙勍 杨玉兰 +5 位作者 孙悍军 彭新 戴静 李娜 马丽涛 单希征 《中华耳科学杂志》 CSCD 北大核心 2014年第3期467-469,共3页
目的全自动化良性阵发性位置性眩晕诊断治疗系统是用于良性阵发性位置性眩晕诊断和治疗的全自动化设备。该设备还可以作为转椅进行速度阶梯试验,探讨使用全自动化良性阵发性位置性眩晕诊断治疗系统进行速度阶梯试验检查结果的可靠性。... 目的全自动化良性阵发性位置性眩晕诊断治疗系统是用于良性阵发性位置性眩晕诊断和治疗的全自动化设备。该设备还可以作为转椅进行速度阶梯试验,探讨使用全自动化良性阵发性位置性眩晕诊断治疗系统进行速度阶梯试验检查结果的可靠性。方法武警总医院眩晕病研究所就诊的眩晕患者48例和正常对照者20例,随机先后使用传统转椅及全自动化良性阵发性位置性眩晕诊断治疗系统进行速度阶梯试验,计算双侧半规管不对称比。Stata软件t检验比较统计数据。结果2种检测方法不对称比的差异无统计学意义。结论全自动化良性阵发性位置性眩晕诊断治疗系统既可以用于良性阵发性位置性眩晕的诊断和复位治疗,又可以进行水平半规管功能检测,临床应用效果可靠. 展开更多
关键词 全自动化良性阵发性位置性眩晕诊断治疗系统 旋转试验 速度阶梯试验
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阶梯习服方案治疗晕动病的临床研究 被引量:3
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作者 张琦 冷辉 《中医眼耳鼻喉杂志》 2018年第2期85-87,共3页
目的 观察应用SRM-Ⅳ型全自动化良性阵发性位置性眩晕诊断治疗系统行阶梯习服方案治疗晕动病的疗效。 方法 选取35例符合纳入标准的晕动病患者行阶梯习服方案。观察患者治疗前、治疗后静态姿势图、晕动病Graybiel评分及有效率。 结果 ... 目的 观察应用SRM-Ⅳ型全自动化良性阵发性位置性眩晕诊断治疗系统行阶梯习服方案治疗晕动病的疗效。 方法 选取35例符合纳入标准的晕动病患者行阶梯习服方案。观察患者治疗前、治疗后静态姿势图、晕动病Graybiel评分及有效率。 结果 治疗后,静态姿势图、晕动病Graybiel评分明显改善( P 〈0.05),有效率达到88.57%。 结论 阶梯习服方案治疗晕动病疗效显著,具有患者易于接受、无副作用、疗效长远等优点,可推广应用。 展开更多
关键词 晕动病 SRM-Ⅳ型全自动化良性阵发性位置性眩晕诊断治疗系统 静态姿势图 晕动病Graybiel评分 阶梯习服方案
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Science Letters:Serum protein fingerprinting coupled with artificial neural network distinguishes glioma from healthy population or brain benign tumor 被引量:6
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作者 刘建 郑树 +2 位作者 余捷凯 张建民 陈喆 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2005年第1期4-10,共7页
To screen and evaluate protein biomarkers for the detection of gliomas (Astrocytoma grade Ⅰ-Ⅳ) from healthy individuals and gliomas from brain benign tumors by using surface enhanced laser desorption/ionization time... To screen and evaluate protein biomarkers for the detection of gliomas (Astrocytoma grade Ⅰ-Ⅳ) from healthy individuals and gliomas from brain benign tumors by using surface enhanced laser desorption/ionization time of flight mass spectrometry (SELDI-TOF-MS) coupled with an artificial neural network (ANN) algorithm. SELDI-TOF-MS protein fingerprinting of serum from 105 brain tumor patients and healthy individuals, included 28 patients with glioma (Astrocytoma Ⅰ-Ⅳ), 37 patients with brain benign tumor, and 40 age-matched healthy individuals. Two thirds of the total samples of every compared pair as training set were used to set up discriminating patterns, and one third of total samples of every compared pair as test set were used to cross-validate; simultaneously, discriminate-cluster analysis derived SPSS 10.0 software was used to compare Astrocytoma grade Ⅰ-Ⅱ with grade Ⅲ-Ⅳ ones. An accuracy of 95.7%, sensitivity of 88.9%, specificity of 100%, positive predictive value of 90% and negative predictive value of 100% were obtained in a blinded test set comparing gliomas patients with healthy individuals; an accuracy of 86.4%, sensitivity of 88.9%, specificity of 84.6%, positive predictive value of 90% and negative predictive value of 85.7% were obtained when patient's gliomas was compared with benign brain tumor. Total accuracy of 85.7%, accuracy of grade Ⅰ-Ⅱ Astrocytoma was 86.7%, accuracy ofⅢ-Ⅳ Astrocytoma was 84.6% were obtained when grade Ⅰ-Ⅱ Astrocytoma was compared with grade Ⅲ-Ⅳ ones (discriminant analysis). SELDI-TOF-MS combined with bioinformatics tools, could greatly facilitate the discovery of better biomarkers. The high sensitivity and specificity achieved by the use of selected biomarkers showed great potential application for the discrimination of gliomas patients from healthy individuals and glioma from brain benign tumors. 展开更多
关键词 ASTROCYTOMA Artificial Neural Network(ANN) SELDI-TOF-MS Protein fingerprint Diagnosis
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Combination of acoustic radiation force impulse imaging, serological indexes and contrast-enhanced ultrasound for diagnosis of liver lesions 被引量:8
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作者 Xiao-Lan Sun Hui Yao +4 位作者 Qiong Men Ke-Zhu Hou Zhen Chen Chang-Qing Xu Li-Wei Liang 《World Journal of Gastroenterology》 SCIE CAS 2017年第30期5602-5609,共8页
AIM To assess the value of combined acoustic radiation force impulse(ARFI) imaging, serological indexes and contrast-enhanced ultrasound(CEUS) in distinguishing between benign and malignant liver lesions. METHODS Pati... AIM To assess the value of combined acoustic radiation force impulse(ARFI) imaging, serological indexes and contrast-enhanced ultrasound(CEUS) in distinguishing between benign and malignant liver lesions. METHODS Patients with liver lesions treated at our hospital were included in this study. The lesions were divided into either a malignant tumor group or a benign tumor group according to pathological or radiological findings. ARFI quantitative detection, serological testing and CEUS quantitative detection were performed and compared. A comparative analysis of the measured indexes was performed between these groups. Receiver operating characteristic(ROC) curves were constructed to compare the diagnostic accuracy of ARFI imaging, serological indexes and CEUS, alone or in different combinations, in identifying benign and malignant liver lesions. RESULTS A total of 112 liver lesions in 43 patients were included, of which 78 were malignant and 34 were benign. Shear wave velocity(SWV) value, serum alpha-fetoprotein(AFP) content and enhancement rate were significantly higher in the malignant tumor group than in the benign tumor group(2.39 ± 1.20 m/s vs 1.50 ± 0.49 m/s, 18.02 ± 5.01 ng/m L vs 15.96 ± 4.33 ng/m L, 2.14 ± 0.21 d B/s vs 2.01 ± 0.31 d B/s; P < 0.05). The ROC curve analysis revealed that the areas under the curves(AUCs) of SWV value alone, AFP content alone, enhancement rate alone, SWV value + AFP content, SWV value + enhancement rate, AFP content + enhancement rate and SWV value + AFP content + enhancement rate were 85.1%, 72.1%, 74.5%, 88.3%, 90.4%, 82.0% and 92.3%, respectively. The AUC of SWV value + AFP content + enhancement rate was higher than those of SWV value + AFP content and SWV value + enhancement rate, and significantly higher than those of any single parameter or the combination of any two of parameters.CONCLUSION The combination of SWV, AFP and enhancement rate had better diagnostic performance in distinguishing between benign and malignant liver lesions than the use of any single parameter or the combination of any two of parameters. It is expected that this would provide a tool for the differential diagnosis of benign and malignant liver lesions. 展开更多
关键词 Combined diagnosis Liver lesions BENIGN MALIGNANT DIFFERENTIATION
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Three cases of retroperitoneal schwannoma diagnosed by EUS-FNA 被引量:9
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作者 Taiki Kudo Hiroshi Kawakami +5 位作者 Masaki Kuwatani Nobuyuki Ehira Hiroaki Yamato Kazunori Eto Kanako Kubota Masahiro Asaka 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第29期3459-3464,共6页
Schwannomas are peripheral nerve tumors that are typically solitary and benign.Their diagnosis is largely based on surgically resected specimens.Recently,a number of case reports have indicated that retroperitoneal sc... Schwannomas are peripheral nerve tumors that are typically solitary and benign.Their diagnosis is largely based on surgically resected specimens.Recently,a number of case reports have indicated that retroperitoneal schwannomas could be diagnosed with endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA).We report the diagnosis of three cases of schwannoma using EUS-FNA.Subjects were two males and one female,ages 22,40,and 46 years,respectively,all of whom were symptom-free.Imaging findings showed well-circumscribed round tumors.However,as the tumors could not be diagnosed using these findings alone,EUS-FNA was performed.Hematoxylin-eosin staining of the resulting tissue fragments revealed bland spindle cells with nuclear palisading.There was no disparity in nuclear sizes.Immunostaining revealed S-100 protein positivity and all cases were diagnosed as schwannomas.Ki-67 indexes were 3%-15%,2%-3%,and 3%,respectively.No case showed any signs of malignancy.As most schwannomas are benign tumors and seldom become malignant,we observed these patients without therapy.All tumors demonstrated no enlargement and no change in characteristics.Schwannomas are almost always benign and can be observed following diagnosis by EUS-FNA. 展开更多
关键词 SCHWANNOMA Endoscopic ultrasonography Fine-needle aspiration Retroperitoneal tumor S100 proteins Ki-67 index
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Small intestinal hemolymphangioma with bleeding:A case report 被引量:20
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作者 Yan-Fei Fang Li-Feng Qiu +2 位作者 Ying Du Zhi-Nong Jiang Min Gao 《World Journal of Gastroenterology》 SCIE CAS CSCD 2012年第17期2145-2146,共2页
Small intestinal hemolymphangioma is a very rare benign tumor.There was only one report of a hemolymphangioma of the pancreas invading to the duodenum until March 2011.Here we describe the first case of small intestin... Small intestinal hemolymphangioma is a very rare benign tumor.There was only one report of a hemolymphangioma of the pancreas invading to the duodenum until March 2011.Here we describe the first case of small intestinal hemolymphangioma with bleeding in a 57-year-old woman.She presented with persistent gastrointestinal bleeding and endoscopy revealed a small intestinal tumor.Partial resection of the small intestine was thus performed and the final pathological diagnosis was hemolymphangioma.We also highlight the difficultly in making an accurate preoperative diagnosis in spite of modern imaging techniques.To arrive at a definitive diagnosis and exclude malignancy,partial resection of the small intestine was considered to be the required treatment. 展开更多
关键词 Hemolymphangioma Small intestine Gastrointestinal bleeding Benign tumor
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The value of MSCT in diagnosis of parotid benign tumor (An analysis of 84 cases) 被引量:1
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作者 Yue Dong Jianlin Wu Ying Ge 《The Chinese-German Journal of Clinical Oncology》 CAS 2010年第6期349-353,共5页
Objective:The purpose of the study was to assess diagnostic performance of MSCT images in patients with parotid benign tumors and provide useful criteria for the characterization of their various pathological types pr... Objective:The purpose of the study was to assess diagnostic performance of MSCT images in patients with parotid benign tumors and provide useful criteria for the characterization of their various pathological types preoperatively. Methods: Retrospectively analyzed clinical and imaging characteristics of 84 cases of pathologically confirmed primary parotid benign tumors. MSCT plain-scan and enhanced-scan were performed in all cases. After injection of 50 mL contrast material at a rate of 3.5 mL/s,spiral CT scans were obtained at arterial and venous phases with scanning delay of 30 s and 75 s,respectively. The attenuation change and enhancement patterns in the tumors were assessed. Quantitatively assess the increased CT number of the tumors in different enhanced-phases compared with the plain-scan and the ratio of increased CT number at venous phase scanning to that at arterial phase scanning also was calculated. Results:In all of 84 cases,40 cases were solitary pleomorphic adenomas,29 cases were adenolyphomas,6 cases were multiple tumors,2 cases were bilateral,15 cases were Basal cell tumor,and one of them had two small lesions. The diameter was 1–5 cm in most of cases,whose margin was smooth and clear,cystic changes in some cases. At two-phase scans,pleomorphic adenomas showed a pattern of slight enhancement and venous enhancement,adenolymphomas showed a pattern of strong enhancement at arterial phase scanning with a decrease at venous phase scanning,basal cell tumor showed a pattern of persistent strong enhancement with commonly significant cystic areas. The ratio of increased CT number was significant different between adenolymphomas and other pathological types. Conclusion: The evaluation of enhancement patterns at two-phase enhanced-scan MSCT is helpful in the differential diagnosis of parotid gland benign tumors. 展开更多
关键词 parotid gland benign tumor computer tomography
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Functional oesophago-gastric junction imaging 被引量:3
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作者 Barry P McMahon Asbjφrn M Drewes Hans Gregersen 《World Journal of Gastroenterology》 SCIE CAS CSCD 2006年第18期2818-2824,共7页
Despite its role in disease there is still no definitive method to assess oesophago-gastric junction competence (OGJ). Traditionally the OGJ has been assessed using manometry with lower oesophageal sphincter pressur... Despite its role in disease there is still no definitive method to assess oesophago-gastric junction competence (OGJ). Traditionally the OGJ has been assessed using manometry with lower oesophageal sphincter pressure as the indicator. More recently this has been shown not to be a very reliable marker of sphincter function and competence against reflux. Disorders such as gastro-oesophageal reflux disease and to a lesser extend achalasia still effects a significant number of patients. This review looks at using a new technique known as impedance planimetry to profile the geometry and pressure in the OGJ during distension of a bag. The data gathered can be reconstructed into a dynamic representation of OGJ action. This has been shown to provide a useful representation of the OGJ and to show changes to the competence of the OGJ in terms of compliance and distensibility as a result of endoluminal therapy. 展开更多
关键词 Oesophagogastric junction Lower oesophageal sphincter COMPETENCE DISTENSIBILITY Functional imaging
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Non-specific histological variant of dysembryoplastic neuroepithelial tumor:a diagnostic challenge
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作者 Yanyang Chen Bin Li +2 位作者 Boning Luo Xiaoying Tian Zhi Li 《Oncology and Translational Medicine》 2016年第2期104-109,共6页
Objective The accurate diagnosis of the non-specific variant of dysembryoplastic neuroepithelial tumor (DNT) is very difficult because it is characterized by absence of the histological hallmark of the "specific gl... Objective The accurate diagnosis of the non-specific variant of dysembryoplastic neuroepithelial tumor (DNT) is very difficult because it is characterized by absence of the histological hallmark of the "specific glioneuronal element" in lesions. We herein present two cases of the non-specific form of DNT to analyze the clinical, radiological, and histological features of this unusual subtype of DNT. Methods A 16-year-old and a 23-year-old patient had been treated for pharmacoresistant epilepsy for several years before undergoing referral to the hospital for further examination and treatment. Magnetic resonance imaging (MRI) revealed that both patients had a small, well-demarcated cystic lesion within the cortex of the brain without obvious contrast enhancement or peritumoral edema. The lesions were totally resected and routinely examined using histological and immunohistochemical analysis. Results Both lesions exhibited similar histological appearances with cyst formation and mural nodule architecture. The glial nodules were mainly composed of oligodendrocyte-like components, and partly of pi^oid cells resembling pilocytic astrocytoma. The cortex adjacent to the lesion in both cases was found to have the histological features of focal cortical dysplasia (FCD) Type I. Immunohistochemically, the oligoden- drocyte-like components were diffusely positive for Syn and Olig-2, but staining for CD34, p53, and IDH1 R132H was negative. The Ki-67 (MIB-1) labeling index was low, approximately 1%. There was no 1p/19q co-deletion in either lesion by fluorescence in situ hybridization (FISH) assay. Neither patient received postoperative adjuvant treatment, and both underwent regular follow-up for at least 24 months. No signs of recurrence or epileptic attacks were observed during the follow-up period. Conclusion The non-specific variant of DNT is a diagnostic challenge for pathologists in clinical practice, and differentiation from some low-grade gliomas needs to be considered. The careful inspection of radio- logic and histopathologic findings, accompanied by analysis of patients' clinical manifestations, may be helpful in making an accurate diagnosis. 展开更多
关键词 brain tumor dysembryoplastic neuroepithelial tumor cortical dysplasia DIFFERENTIALDIAGNOSIS
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American Family Physician2014年12月目次选登
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作者 本刊编辑部 《中国全科医学》 CAS CSCD 北大核心 2015年第2期235-235,共1页
December1,2014 Common Questions about the Diagnosis and Management of Benign Prostatic Hyperplasia关于良性前列腺增生诊断和治疗的常见问题 Schizophrenia 精神分裂症 Incidentalomas : Initial Management偶发事件的初始管理。
关键词 DIAGNOSIS 良性前列腺增生诊断 精神分裂症 偶发事件
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The diagnostic value of transrectal ultrasonographic features in prostate cancer
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作者 Xiaoli Zou Guang Yang Hui Wang 《The Chinese-German Journal of Clinical Oncology》 CAS 2012年第4期229-232,共4页
Objective:The aim of the study was to detect the valuable ultrasonographic features in diagnosing prostate cancer.Methods:The patients who underwent transrectal ultrasound in the period from May 2005 to October 2009 a... Objective:The aim of the study was to detect the valuable ultrasonographic features in diagnosing prostate cancer.Methods:The patients who underwent transrectal ultrasound in the period from May 2005 to October 2009 at the 1st Affiliated Hospital of Dalian Medical University,China,were included,with needle biopsy diagnosis for patients with the prostate cancer and prostatic hyperplasia.Seventy-four cases of prostate cancer were diagnosed as adenocarcinoma,compared with 51 cases diagnosed as prostatic hyperplasia.Retrospective analysis of patients with transrectal ultrasound were done,comparing the difference between the two groups in the echo level (hypoechogenic),outlines (ill-defined margin),posterior acoustic attenuation,periphery halo,microcalcification incidence,the blood supply level,peak systolic velocity (Vs) and resistance index (RI).Results:The ratios of hypoechogenic lesions in the prostate cancer group and prostatic hyperplasia group were 56.76% and 35.90%,respectively (P<0.05),the ratios of irregular outlines were 85.14% and 15.38% respectively (P<0.05),the ratios of microcalcification were 39.19% and 10.26%,respectively (P < 0.05),the ratios of posterior acoustic attenuation were 41.89% and 12.82%,respectively (P<0.05),and the ratios of periphery halo were 35.14% and 38.46% respectively (P>0.05).Vs of the two groups were (44.00 ± 15.30) cm/s and (17.32 ± 4.65) cm/s,respectively (P<0.05).RI of the two groups were 0.76 ± 0.10,and 0.51 ± 0.03 respectively (P<0.05).The significant correlation was designated in the blood supply level between the prostate cancer group and prostatic hyperplasia group (r=-0.388,P<0.01).Higher revascularization grade was seen in the prostate cancer group compared to benign prostatic hyperplasia group.Conclusion:(1) The significant roles for diagnosing prostate cancer are hypoechogenic,irregular outlines,spiculation,microcalcification,high revascularization grade,posterior acoustic attenuation,high Vs and high RI.(2) It could not help in diagnosing prostate cancer with ultrasonographic periphery halo or not. 展开更多
关键词 transrectal ultrasound prostate cancer DIAGNOSIS
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