MCS （mechanical circulatory support） has shown great efficacy in treatment of respiratory mid cardiovascular diseases when conventional therapy is insufficient. The use of ECMO （extracolporeal membrane oxygenation...MCS （mechanical circulatory support） has shown great efficacy in treatment of respiratory mid cardiovascular diseases when conventional therapy is insufficient. The use of ECMO （extracolporeal membrane oxygenation） for the treatment of cardiogenic shock secondary to sepsis is still controversial. Studies have shown that ECMO should be considered as a valuable therapeutic option in cases of refractory cardiovascular dysfunction in severe septic patients, although more studies ale needed to consolidate its efficacy. We report the case of two patients, without previous history of cardiopathy, subjected to temporary MCS, with use of ECMO for the treatment of refractory cardiogenic shock secondary to sepsis.展开更多
Cytogenetic studies have shown that the genus Astyanax has extensive karyotypic variability among species and many are the works developed about this group in different river basins in Brazil. The Tangara da Serra ar...Cytogenetic studies have shown that the genus Astyanax has extensive karyotypic variability among species and many are the works developed about this group in different river basins in Brazil. The Tangara da Serra area （Mato Grosso State, Brazil）, which contains tributaries of both Amazon and Upper Paraguay River basins is, therefore, a natural watershed. Thus, in this work, the karyotypes of three species of Astyanax from the Sepotuba River＇s tributary streams were analyzed by using conventional methods of chromosome analysis. Astyanax marionae presented 2n =48（12m＋ 10sm＋ 12st＋ 14a） and NF （fundamental number） = 82 with evident heterochromatin in several chromosomal regions. Astyanax cf. asuncionensis presented 2 n = 50 （20m ＋ 12sm ＋ 6st ＋ 12a）, NF = 94 chromosomes and with evident heterochromatin in few chromosomes and Ag-NOR in one chromosome pair. Astyanax cp. scabripinnis presented 2 n = 50 （12m ＋ 10sm ＋ 10st ＋ 18a）, NF = 82 with evident heterochromatin at most of the chromosomes in pericentromeric region and a strongly marked block on a telocentric chromosome pair. The Ag-NORs were observed near the heterochromatic region. The karyotypic differences found, probably occurred by chromosomal rearrangements, resulting in a heterogeneous model of chromosomal evolution who probably involved both Robertsonian chromosomal rearrangements to A. marionae, as not Robertsonian to other Astyanax species. This indicates that although these species share the same hydrographic basin （Upper Paraguay） are isolated in different microbasins and the absence in the gene flow may have allowed the establishment of independent rearrangements in each population.展开更多
Acetamiprid is a novel neonicotinoid insecticide invented by Nippon Soda Co., Ltd.. To explore the possibility of acetamiprid as larvicide of mosquitoes, lethal and sublethal effects of acetamiprid on the larvae of ...Acetamiprid is a novel neonicotinoid insecticide invented by Nippon Soda Co., Ltd.. To explore the possibility of acetamiprid as larvicide of mosquitoes, lethal and sublethal effects of acetamiprid on the larvae of Culex pipiens pallens were studied by immersion method in the laboratory. The results indicated that the larvae of Culex pipiens pallens were sensitive to acetamiprid. The mortality of larvae peaked at 72 h after treatment. The 1st instar larvae was the most susceptible to acetamiprid, and the 4th instar larvae was the most tolerant to acetamiprid, the LC 50 values were 0.020 mg/L and 0.296 mg/L at 72 h after treatment, respectively. Sublethal concentrations of acetamiprid could delay the development of larvae and decrease the weight of pupa. We suggested that acetamiprid is a safe and effective substitute for the using larvicides of mosquitoes.展开更多
Perylene diimide （PDI） derivatives, due to their special opto-electronic property, have been successfully utilized in organic field-effect transistor （OFET）, solar cells, and as non-fullerene acceptor and others, ...Perylene diimide （PDI） derivatives, due to their special opto-electronic property, have been successfully utilized in organic field-effect transistor （OFET）, solar cells, and as non-fullerene acceptor and others, while few cases in organic light-emitting diodes （OLEDs）. In this work, six perylene bisimide-based red emitters, N＇N＇-bis（2-decyltetradecyl）-1-（[1,1′：3′,1″-terphenyl]-5′-yl）perylene-3,4,9,10-diimide （STPH）, N＇N＇-bis（2-decyltetradecyl）-1,7-bis（[1,1′：3′,1″-terphenyl]-5′-yl）perylene-3,4,9,10-diimide （DTPH）, N,N＇- bis（2-decyltetradecyl）-1-（5′-phenyl-[1,1′：3′,1″-terphenyl]-4-yl）perylene-3,4,9,10-diimide （STRPH）, N,N′- bis（2-decyltetradecyl）-1,7-bis（5′-phenyl-[ 1 ,1′：3′,1＂-terphenyll-4-yl）perylene-3,4,9,10-diimide （DTRPH）, N,N′-bis（2-decyltetradecyl）-1-（4-（2,2-diphenylvinyl）phenyl）perylene-3,4,9,10-diimide/STTPE） and N,N＇- bis（2-decyltetradecyl）-1,7-bis（4-（2,2-diphenykvinyl）phenyl）perylene-3,4,9,10-diimide （DTTPE）, with the excellent chemical, thermal and photo-chemical stability, are synthesized through the convenient Suzuki coupling reaction, in which, the fluorescent properties can be modified easily from ACQ to AIE by just simply changing the bulky volume of the introduced aromatic substituents. After being fabricated into organic light-emitting diodes, STRPH exhibits the best performance with the maximum luminescence, power efficiency, current efficiency and external quantum efficiency of 1,948 cd m-2, 2.04lm W-1, 5.85 cd A-1, 4.93% at Commission Internationale de L＇Eclairage （CIE） coordinates of （0.56, 0.34）, as the result of the high efficient energy transfer and good energy match achieved in the device.展开更多
The Himalayan leucogranite occurs as two extensive(>1000 km) E-W trending belts on the Tibetan Plateau with the unique features. The leucogranite comprised biotite granite, two-mica/muscovite granite, tourmaline gr...The Himalayan leucogranite occurs as two extensive(>1000 km) E-W trending belts on the Tibetan Plateau with the unique features. The leucogranite comprised biotite granite, two-mica/muscovite granite, tourmaline granite and garnet granite, which have been identified in previous studies, as well as albite granite and granitic pegmatite that were identified in this investigation. Fifteen leucogranite plutons were studied and 12 were found to contain rare-metal bearing minerals such as beryl(the representative of Be mineralization), columbite-group minerals, tapiolite, pyrochlore-microlite, fergusonite, Nb-Ta rutile(the representative of Nb-Ta mineralization), and cassiterite(the representative of Sn mineralization) mainly based on the field trip,microscope observation and microprobe analysis. The preliminary result shows that the Himalayan leucogranite is commonly related to the rare-metal mineralization and warrants future investigation. Further exploration and intensive research work is important in determining the rare-metal resource potential of this area.展开更多
Caffeine is one of methyl xanthine compounds,which has the similar mode of action as ryanodine receptor insecticide.In order to find novel and efficient insecticide,structural modification of certain methyl xanthine c...Caffeine is one of methyl xanthine compounds,which has the similar mode of action as ryanodine receptor insecticide.In order to find novel and efficient insecticide,structural modification of certain methyl xanthine compounds was made by introducing some common pesticidal active moieties into the structure of caffeine.Eleven novel methyl xanthine compounds were synthesized and characterized by 1H nuclear magnetic resonance（1H NMR）,elemental analylsis or high-resolution mass spectrometry（HRMS）.According to the biological activity results,it was found that these new compounds show moderate activity towards Mythimna separata Walker and Culex pipiens pallens.For example,compound 2d shows a lethality rate of 40％ at 200 mg/L towards Mythimna separata Walker,compounds 2i and 2f show 56.7％ and 53.3％ lethality rates at 2 mg/L towards Culex pipiens pallens,which are all better than caffeine.In addition,some compounds of them show moderate antifungal activity to some plant pathogenous fungi.展开更多
文摘MCS （mechanical circulatory support） has shown great efficacy in treatment of respiratory mid cardiovascular diseases when conventional therapy is insufficient. The use of ECMO （extracolporeal membrane oxygenation） for the treatment of cardiogenic shock secondary to sepsis is still controversial. Studies have shown that ECMO should be considered as a valuable therapeutic option in cases of refractory cardiovascular dysfunction in severe septic patients, although more studies ale needed to consolidate its efficacy. We report the case of two patients, without previous history of cardiopathy, subjected to temporary MCS, with use of ECMO for the treatment of refractory cardiogenic shock secondary to sepsis.
文摘Cytogenetic studies have shown that the genus Astyanax has extensive karyotypic variability among species and many are the works developed about this group in different river basins in Brazil. The Tangara da Serra area （Mato Grosso State, Brazil）, which contains tributaries of both Amazon and Upper Paraguay River basins is, therefore, a natural watershed. Thus, in this work, the karyotypes of three species of Astyanax from the Sepotuba River＇s tributary streams were analyzed by using conventional methods of chromosome analysis. Astyanax marionae presented 2n =48（12m＋ 10sm＋ 12st＋ 14a） and NF （fundamental number） = 82 with evident heterochromatin in several chromosomal regions. Astyanax cf. asuncionensis presented 2 n = 50 （20m ＋ 12sm ＋ 6st ＋ 12a）, NF = 94 chromosomes and with evident heterochromatin in few chromosomes and Ag-NOR in one chromosome pair. Astyanax cp. scabripinnis presented 2 n = 50 （12m ＋ 10sm ＋ 10st ＋ 18a）, NF = 82 with evident heterochromatin at most of the chromosomes in pericentromeric region and a strongly marked block on a telocentric chromosome pair. The Ag-NORs were observed near the heterochromatic region. The karyotypic differences found, probably occurred by chromosomal rearrangements, resulting in a heterogeneous model of chromosomal evolution who probably involved both Robertsonian chromosomal rearrangements to A. marionae, as not Robertsonian to other Astyanax species. This indicates that although these species share the same hydrographic basin （Upper Paraguay） are isolated in different microbasins and the absence in the gene flow may have allowed the establishment of independent rearrangements in each population.
文摘Acetamiprid is a novel neonicotinoid insecticide invented by Nippon Soda Co., Ltd.. To explore the possibility of acetamiprid as larvicide of mosquitoes, lethal and sublethal effects of acetamiprid on the larvae of Culex pipiens pallens were studied by immersion method in the laboratory. The results indicated that the larvae of Culex pipiens pallens were sensitive to acetamiprid. The mortality of larvae peaked at 72 h after treatment. The 1st instar larvae was the most susceptible to acetamiprid, and the 4th instar larvae was the most tolerant to acetamiprid, the LC 50 values were 0.020 mg/L and 0.296 mg/L at 72 h after treatment, respectively. Sublethal concentrations of acetamiprid could delay the development of larvae and decrease the weight of pupa. We suggested that acetamiprid is a safe and effective substitute for the using larvicides of mosquitoes.
基金supported by the National Natural Science Foundation of China (51673151, 61575146 and 21325416)the Open Fund of the State Key Laboratory of Luminescent Materials and Device in South China University of Technology (2017skllmd-04)
文摘Perylene diimide （PDI） derivatives, due to their special opto-electronic property, have been successfully utilized in organic field-effect transistor （OFET）, solar cells, and as non-fullerene acceptor and others, while few cases in organic light-emitting diodes （OLEDs）. In this work, six perylene bisimide-based red emitters, N＇N＇-bis（2-decyltetradecyl）-1-（[1,1′：3′,1″-terphenyl]-5′-yl）perylene-3,4,9,10-diimide （STPH）, N＇N＇-bis（2-decyltetradecyl）-1,7-bis（[1,1′：3′,1″-terphenyl]-5′-yl）perylene-3,4,9,10-diimide （DTPH）, N,N＇- bis（2-decyltetradecyl）-1-（5′-phenyl-[1,1′：3′,1″-terphenyl]-4-yl）perylene-3,4,9,10-diimide （STRPH）, N,N′- bis（2-decyltetradecyl）-1,7-bis（5′-phenyl-[ 1 ,1′：3′,1＂-terphenyll-4-yl）perylene-3,4,9,10-diimide （DTRPH）, N,N′-bis（2-decyltetradecyl）-1-（4-（2,2-diphenylvinyl）phenyl）perylene-3,4,9,10-diimide/STTPE） and N,N＇- bis（2-decyltetradecyl）-1,7-bis（4-（2,2-diphenykvinyl）phenyl）perylene-3,4,9,10-diimide （DTTPE）, with the excellent chemical, thermal and photo-chemical stability, are synthesized through the convenient Suzuki coupling reaction, in which, the fluorescent properties can be modified easily from ACQ to AIE by just simply changing the bulky volume of the introduced aromatic substituents. After being fabricated into organic light-emitting diodes, STRPH exhibits the best performance with the maximum luminescence, power efficiency, current efficiency and external quantum efficiency of 1,948 cd m-2, 2.04lm W-1, 5.85 cd A-1, 4.93% at Commission Internationale de L＇Eclairage （CIE） coordinates of （0.56, 0.34）, as the result of the high efficient energy transfer and good energy match achieved in the device.
基金supported by the National Natural Science Foundation of China (Grants Nos. 41230315 and 41130313)the Fundamental Research Funds for the Central Universities (Grants No. 020614380057)
文摘The Himalayan leucogranite occurs as two extensive(>1000 km) E-W trending belts on the Tibetan Plateau with the unique features. The leucogranite comprised biotite granite, two-mica/muscovite granite, tourmaline granite and garnet granite, which have been identified in previous studies, as well as albite granite and granitic pegmatite that were identified in this investigation. Fifteen leucogranite plutons were studied and 12 were found to contain rare-metal bearing minerals such as beryl(the representative of Be mineralization), columbite-group minerals, tapiolite, pyrochlore-microlite, fergusonite, Nb-Ta rutile(the representative of Nb-Ta mineralization), and cassiterite(the representative of Sn mineralization) mainly based on the field trip,microscope observation and microprobe analysis. The preliminary result shows that the Himalayan leucogranite is commonly related to the rare-metal mineralization and warrants future investigation. Further exploration and intensive research work is important in determining the rare-metal resource potential of this area.
基金Supported by the National Basic Research Program of China（No.2010CB126106）, the National Natural Science Foundation of China（Nos.21272129, 21372133）, the National Key Technologies Research and Development Program, China（No. 2011BAE06B05-3） and Specialized Research Fund for the Doctorial Program of Higher Education, China（No.20110031110017）.
文摘Caffeine is one of methyl xanthine compounds,which has the similar mode of action as ryanodine receptor insecticide.In order to find novel and efficient insecticide,structural modification of certain methyl xanthine compounds was made by introducing some common pesticidal active moieties into the structure of caffeine.Eleven novel methyl xanthine compounds were synthesized and characterized by 1H nuclear magnetic resonance（1H NMR）,elemental analylsis or high-resolution mass spectrometry（HRMS）.According to the biological activity results,it was found that these new compounds show moderate activity towards Mythimna separata Walker and Culex pipiens pallens.For example,compound 2d shows a lethality rate of 40％ at 200 mg/L towards Mythimna separata Walker,compounds 2i and 2f show 56.7％ and 53.3％ lethality rates at 2 mg/L towards Culex pipiens pallens,which are all better than caffeine.In addition,some compounds of them show moderate antifungal activity to some plant pathogenous fungi.
