A comprehensive assessing method based on the principle of the gray system theory and gray relational grade analysis was put forward to optimize water consumption forecasting models. The method provides a better accur...A comprehensive assessing method based on the principle of the gray system theory and gray relational grade analysis was put forward to optimize water consumption forecasting models. The method provides a better accuracy for the assessment and the optimal selection of the water consumption forecasting models. The results show that the forecasting model built on this comprehensive assessing method presents better self-adaptability and accuracy in forecasting.展开更多
The solvent selection methodology developed earlier by. Gani （tal. （Comp. Chem. Eng., 2005）has been extended to handle multi-step reaction systems. The solvent selection problem was formulated based on the methodol...The solvent selection methodology developed earlier by. Gani （tal. （Comp. Chem. Eng., 2005）has been extended to handle multi-step reaction systems. The solvent selection problem was formulated based on the methodology guidelines, and solved using ICAS software tool. A list with solvent candidates is generated so that it can be further investigated experimentally. Comments and clarifications from chemists have been incorporated into the problem forrnulations to clarify the role of the solvents in the chemistry and potential reactivity issues. Highly promising results were obtained, in accordance with. industrial process data.展开更多
Acetylspiramycin（ASPM）,a 16-membered basic macrolide antibiotic,is the acetylated derivative of spiramycin.In addition to the four main components,more than seventy minor components could be present in ASPM.Thus,it ...Acetylspiramycin（ASPM）,a 16-membered basic macrolide antibiotic,is the acetylated derivative of spiramycin.In addition to the four main components,more than seventy minor components could be present in ASPM.Thus,it is a challenge to obtain a baseline separation of ASPM components.Meanwhile,in some cases it was found that the results obtained by different brands of C_（18） columns were significantly different,indicating the necessity of a rational column selection for the separation of ASPM components.In this paper,we attempted to facilitate column selection for the analysis of ASPM using the database of the column characterization system established by Leuven University.With the CAPCELL PAK MG C_（18）（250 mm×4.6 mm,5μm） as the reference column,three groups of columns（F2 group：similar selectivity;2F6：intermediate ranked group;F6 group： different selectivity,compared to the reference column） were selected,and their performances in the separation of ASPM components were evaluated under the chromatographic conditions described in Chinese Pharmacopoeia monograph.A good relationship was demonstrated between the ranking of columns and their selectivity in the separation of ASPM components,indicating the column classification system established by Leuven University was a helpful tool in the selection of suitable columns for the analysis of ASPM,a complex mixture of basic compounds.展开更多
基金Project(2003BA808A15-2-4) supported by the National Scientific and Technologies Key Task Program
文摘A comprehensive assessing method based on the principle of the gray system theory and gray relational grade analysis was put forward to optimize water consumption forecasting models. The method provides a better accuracy for the assessment and the optimal selection of the water consumption forecasting models. The results show that the forecasting model built on this comprehensive assessing method presents better self-adaptability and accuracy in forecasting.
基金PRISM FP6 Marie Curie Research Training Network (MRTN-CT-2004-512233)
文摘The solvent selection methodology developed earlier by. Gani （tal. （Comp. Chem. Eng., 2005）has been extended to handle multi-step reaction systems. The solvent selection problem was formulated based on the methodology guidelines, and solved using ICAS software tool. A list with solvent candidates is generated so that it can be further investigated experimentally. Comments and clarifications from chemists have been incorporated into the problem forrnulations to clarify the role of the solvents in the chemistry and potential reactivity issues. Highly promising results were obtained, in accordance with. industrial process data.
文摘Acetylspiramycin（ASPM）,a 16-membered basic macrolide antibiotic,is the acetylated derivative of spiramycin.In addition to the four main components,more than seventy minor components could be present in ASPM.Thus,it is a challenge to obtain a baseline separation of ASPM components.Meanwhile,in some cases it was found that the results obtained by different brands of C_（18） columns were significantly different,indicating the necessity of a rational column selection for the separation of ASPM components.In this paper,we attempted to facilitate column selection for the analysis of ASPM using the database of the column characterization system established by Leuven University.With the CAPCELL PAK MG C_（18）（250 mm×4.6 mm,5μm） as the reference column,three groups of columns（F2 group：similar selectivity;2F6：intermediate ranked group;F6 group： different selectivity,compared to the reference column） were selected,and their performances in the separation of ASPM components were evaluated under the chromatographic conditions described in Chinese Pharmacopoeia monograph.A good relationship was demonstrated between the ranking of columns and their selectivity in the separation of ASPM components,indicating the column classification system established by Leuven University was a helpful tool in the selection of suitable columns for the analysis of ASPM,a complex mixture of basic compounds.
