针刺加艾药灸治疗强直性脊柱炎疗效分析

目的:探讨针刺加艾药灸治疗强直性脊柱炎的临床效果。方法:将符合针刺加艾药灸综合疗法治疗的90例强直性脊柱炎患者作为研究对象,观察患者治疗前后的病情变化,对比脊柱活动度、胸廓活动度及晨僵持续时间等指标值,评估该疗法的治疗效果。结果:90例患者中,45例显效、42例有效及3例无效,总有效率96.7%。治疗后,患者的生化指标值相对治疗前有显著改善,差异具有统计学意义(P<0.05)。结论:针灸综合疗法应用于强直性脊柱炎的治疗效果明显,该疗法具有实用性强、安全性高等优点,值得在临床上推广应用。

麝艾药棒节律灸治疗小儿癫痫

麝艾药棒灸是笔者秉承蜀中名家吴棹仙、刁泰芬、雷德安、王静安等诸位先生所授之外治经验，结合自己46年临证实践，创制的一种外治方法。近20年来．笔者用此法治疗多种小儿疑难疾病，颇有所获。今将麝艾药棒灸治疗小儿癫痫经验介绍如下，仅作抛砖．请同道斧正。

孙英霞治疗陈旧性踝关节扭伤经验

孙英霞从事针灸临床、教学及科研工作十余年,积累了丰富的临床经验,擅长利用隔药大艾炷灸神阙及毫火针,并结合其独特的针刺补泻手法烧山火,治疗陈旧性踝关节扭伤取得了显著的疗效。

An Analysis of Therapeutic Effect of Drug Acupoint Application in 209 Cases of Allergic Asthma

Both therapies of traditional crude herb moxibustion and drug acupoint application were used in 209 cases of allergic asthma to compare their long-term and short-term therapeutic effects and to analyze the relationship between clinic therapeutic effects of both therapies and differential types of the disease. The results showed that the short-term total effective rate in the group of drug acupoint application was higher than that in the group of traditional crude herb moxibustion, the therapeutic effects of drug acupoint application being closely related to differential types. Analysis also shows the best short-term therapeutic effect was in the type of heat in the lung while the poorest effect in the type of deficiency of the kidney-yang.

OBSERVATION ON THE THERAPEUTIC EFFECT OF BIRD-PECKING MOXIBUSTION OF SPECIFIC ACUPOINTS IN THE TREATMENT OF FUNCTIONAL DYSPEPSIA

Objective: To observe the therapeutic effect of moxibustion of some specific acupoints for treatment of functional dyspepsia (FD, qi-distension type). Methods:A total of 50 cases of FD patients were randomly divided into treatment group (n=26) and medication group (n=24). In treatment group, bird-pecking moxibustion was applied to Zhongwan (CV 12), Qihai (CV 6), Neiguan (PC 6) and Gongsun (SP 4) 5～6 times in every treatment till the local skin got flush. The treatment was given once daily, continuously for 10 days. In control group, the patients were ordered to take Motilium 10 mg/time, 3 times daily. Following 10 days’ treatment the therapeutic effect was assessed.Results:After treatment, of the 26 cases in treatment group, 11 (42.3%) were cured, 7 (26.92%) had remarkable improvement in their symptoms, 6 (23.07%) had improvement and 2 (7.69%) failed, with a total effective rate of 92.31%. Of the 24 cases in medication group, 9 (37.50%) were cured, 6 (25.00%) experienced remarkable improvement in their symptoms, 6 (25.00%) were improved and 3 (12.50%) failed, with a total effective rate of 87.50%. Comparison between two groups showed that the therapeutic effect of moxibustion was significantly superior to that of medication (P<0.05). In addition, the difference value of the therapeutic effect index (TEI) between post-and pre-treatment in treatment group was also significantly higher than that of medication group (P<0.05). Conclusion: Bird-pecking moxibustion of specific acupoints can effectively improve clinical symptoms of FD patients.

Diarrhea

Institute of Acupuncture and Moxibustion,China Academy of Traditional Chinese Medicine Beijing 100700

CLINICAL OBSERVATION ON STAGE-AIDED TREATMENT OF 62 CASES OF PERIPHERAL FACIAL PARALYSIS WITH ACUPUNCTURE,MOXIBUSTION AND CUPPING

Objective: To probe the best therapy for peripheral facial paralysis. Methods: A total of 122 cases of facial paralysis patients were randomized into treatment group (n=62, treating the disease by stages) and control group (n=60). For patients at the acute stage in treatment group, main point Yifeng (TE 17) was pricked first, followed by performing cupping and moxibustion, for patients at the resting stage, main point Hegu (LI 4) was punctured with reducing needling method, combined with other acupoints in the light of the concrete situations. For patients at the restoration stage, main point Zusanli (ST 36) was punctured with reinforcing method in combination with seven-star-needle tapping at the local affected region. Patients of control group were treated with routine method by puncturing Fengchi (GB 20), Yifeng (TE 17), Jiache (ST 6), Hegu (LI 4), Taichong (LR 3), etc.. The treatment was conducted once daily, with 10 days being a therapeutic course. Results: Following 3 courses of treatment, of the 62 cases in treatment group, 44 (70.9%) were cured, 12 (19.4%) had remarkable improvement in their symptoms and signs, 6 (9.7%) had amelioration, with the cure plus markedly effective rate being 90.3%; of the 60 cases in control group, 30 (50.0%) were cured, 12 (20.0%) had apparent improvement, 16 (26.7%) had amelioration, and the rest 2 (3.3%) failed in the treatment, with the cure plus markedly effective rate being 70.0%. Ridit analysis showed that the cure rate and cure plus markedly effective rate of treatment group were significantly higher than those of control group (P<0.05). Conclusion: Stage-aided acupuncture treatment is superior to routine treatment for facial palsy.

TREATMENT OF ANGINA PECTORIS WITH MEDICINAL PLASTER FIXED AT ACUPOINTS -A Report of 54 Cases

That the diseases in the interior can be treated at the exterior is one of the therapeutic methods of traditional Chinese medicine. Pretty good results has been obtained in treating the patients of angina pectoris with medicinal plaster fixed at acupoints. This is reported as follows.

Effect of moxibustion on expressions of HO-1 and MCP-3 protein in colon of rats with Crohn's disease

Objective： To observe the effect of moxibustion therapy on heme oxygenase-1（HO-1） and monocyte chemoattractant protein-3（MCP-3） protein expressions in the colonic mucosa of rats with Crohn＇s disease（CD）, and to explore the intestinal mucosal immune mechanism of moxibustion therapy in treating CD. Methods： The CD rat model was established using the internationally accepted Morris method. The rats were randomly divided into a model group, a herbal cake-partitioned moxibustion group, a mild moxibustion group, a cigarette moxibustion group and a hot compress group, which were compared with the normal group. Except the normal group and the model group, rats in the other groups accepted different moxibustion therapies on bilateral Tianshu（ST 25）. Hematoxylin-eosin（HE） staining was conducted and the pathological changes of the colon were observed under light microscope; the expressions of HO-1 and MCP-3 protein in rat＇s colonic mucosa were determined by immunohisto-chemistry. Results： Compared with the normal group, rats in the model group showed mucosal defect, villus destruction or loss, submucosal congestion and edema, glandular destruction or disappearance, reduced goblet cells, ulcer formation, significantly increased positive target area and positive target integral optical density of HO-1 and MCP-3 protein expression（all P〈0.01）. After treatment, compared with the model group, colonic mucosa was significantly improved in the herbal cake-partitioned moxibustion group and the mild moxibustion group, which mainly showed that the intestinal glands were arranged regularly, ulcer surfaces were covered by the neoformative epitheliums, or intestinal ulcers were replaced by the nascent granulation tissue, and submucosal edema was alleviated, with a small amount of inflammatory cell infiltration. The total areas and the integral optical densities of the positive targets for rat＇s colonic mucosa HO-1 and MCP-3 protein expressions were decreased（all P〈0.01）. Compared with the cigarette moxibustion group and the hot compress group, the total areas and the integral optical densities of the positive targets for rat＇s colonic mucosa HO-1 and MCP-3 protein expressions were significantly decreased（all P〈0.01） in the herbal cake-partitioned moxibustion group and the mild moxibustion group. Conclusion： Herbal cake-partitioned moxibustion and mild moxibustion can significantly improve the inflammatory response of colonic mucosa in CD rats. It can down-regulate the expressions of HO-1 and MCP-3 proteins in the colonic mucosa of CD rats, which may be one of the mechanism in intestinal mucosal immunity caused by moxibustion therapy.

Clinical Observation of Diabetic Peripheral Neuropathy Treated by Moxibustion plus Mecobalamin

Objective： To evaluate the clinical efficacy of moxibustion plus Mecobalamin in treating diabetic peripheral neuropathy. Methods： Eighty subjects were equally allocated into combination and control groups. On the basis of the same basic treatment, the combination group was treated by moxibustion plus Mecobalamin and the control group simply by Mecobalamin. Treatment lasted 3 months. Nerve conduction velocity and symptom severity were compared between pre-treatment and post-treatment. Results： Nerve conduction velocity was improved in both combination and control groups and more obviously in the combination group. The marked effective rate, effective rate and ineffective rate were respectively 52.5%, 32.5% and 15.0% in the combination group and 35.0%, 27.5% and 37.5% in the control group. There were statistically significant differences between the two groups （P〈0.01 or P〈0.05）. Conclusion： Based on a basic treatment, moxibustion plus Mecobalamin is superior to simple Mecobalamin in treating diabetic peripheral neuropathy.

Clinical observation on prevention of chemotherapy infection in gastric cancer by moxa-stick moxibustion plus rhG-CSF and its effect on immune function

Objective:To observe the effect of moxa-stick moxibustion plus recombinant human granulocyte-colony stimulating factor(rhG-CSF)in preventing chemotherapy infection in gastric cancer and its effect on immune function.Methods:A total of 70 patients with gastric cancer treated by chemotherapy were randomly divided into an observation group and a control group,with 35 cases in each group.The control group was given rhG-CSF,and the observation group was given additional moxa-stick moxibustion on the basis of rhG-CSF.Both groups were treated for 2 chemotherapy cycles,totally 6 weeks.The number of patients with infection,the duration of infection and the duration of continuous use of antibiotics were observed.The leukocytes and granulocytes counts,the levels of tumor necrosis factor-a(TNF-a)and interferon-γ(IFN-γ)were measured before and after treatment,and the levels of CD4,CD8 and natural killer(NK)cells were analyzed.Results:The infection rate of the observation group was significantly lower than that of the control group(P<0.05),and the duration of infection and the duration of continuous use of antibiotics were also shorter(P<0.05).After treatment,the leukocytes and granulocytes counts in the two groups were higher than those before treatment(all P<0.05).After treatment,the levels of TNF-α and IFN-γ of the patients in the two groups were improved(all P<0.05),and there were significant differences between the observation group and the control group(P<0.05).After treatment,the numbers of CD4,CD8,and NK cells in the observation group increased significantly(all P<0.05);but the changes in the control group were not significant(P>0.05).Conclusion:Moxa-stick moxibustion plus rhG-CSF can significantly reduce the incidence and severity of chemotherapy infection in gastric cancer,increase the leukocytes and granulocytes counts,and regulate the levels of inflammatory factors,which may be related to the improvement of the immune function of the patients.

Effect of mild moxibustion on cancer-related fatigue,serum ghrelin and adiponectin in patients undergoing chemotherapy after colorectal cancer surgery

Objective To observe the effect of mild moxibustion on cancer-related fatigue,serum ghrelin and adiponectin in patients undergoing chemotherapy after colorectal cancer surgery.Methods Seventy patients were divided into a control group and an observation group according to the random number table method,with 35 cases in each group.Patients in both groups were treated with conventional FOLFOX4 chemotherapy regimen.Patients in the control group also received routine treatments such as symptomatic treatment of complications,health education,nutritional support,and exercise intervention.Patients in the observation group received mild moxibustion on the basis of interventions used in the control group.The Piper fatigue scale-revision(PFS-R),Karnofsky performance status(KPS)and spleen and kidney yang deficiency syndrome were scored,and serum ghrelin and adiponectin levels were measured before and after treatment.Results After treatment,total score of PFS-R in the control group did not change significantly(P>0.05),while in the observation group it was significantly reduced(P<0.05)and lower than that in the control group(P<0.05);KPS scores in both groups were increased(both P<0.05),and it was significantly higher in the observation group than in the control group(P<0.05);total score of spleen and kidney yang deficiency syndrome in the control group did not change significantly(P>0.05),while it was significantly reduced in the observation group(P<0.05)and lower than that in the control group(P<0.05);serum ghrelin and adiponectin levels in the control group had no significant changes(both P>0.05),but the levels were significantly increased in the observation group(both P<0.05)and higher than those in the control group(both P<0.05).Conclusion Based on the routine treatments,mild moxibustion can relieve fatigue,improve quality of life,and improve the symptoms of spleen and kidney yang deficiency in patients undergoing chemotherapy after colorectal cancer surgery,which may be related to the regulation of serum ghrelin and adiponectin levels.

Experience on Treatment of Infantile Asthma by Acupuncture plus Herbal Medicine

Asflmla is commonly termed ＂roaring disease＂, referring to gurgling wilh slmtum in tile throat, characterized by difficult and rapid breaflling. Infantile asfluna belongs to a kind of ronchitis, and would occur repeatedly and become a chronic disease. Because the defending function of the respiratoo＇ systeln in children has not been complete and tile imnmne system of the respiratoD tract has not been matured, file hyperactive inflammatoxy reaction would happen, if stinmlated by inducing thctors of se allergen, infection or emotional depression, so as to develop dyspnea, increased secretion of phlegm, and spasm of bronclfial smooth nmscle, hindering the normal ventilation of air and resulting in asthma, manifested by the clinical symptolns of dyspnea, shortness of breath, unsmooth expectoration, and wheezing. In severe cases, patients may also present with cyanosis of the lips, facial puffiness and breathing an open mouth and raised shoulders. Before each seizure, SOlne indicating signs would occur in some patients with asthma, such as itching sensation in the nose, itching sensation in tile eyelids, sneezing, lacrimation, dry cough, and sore throat, etc., caused by infection of the respiratory tract. If induced by alle to food, there are oen symptoms of vomiting, abdominal pain and urticaria. At this moment, tilt physical examinations should find pale and edema in nasal mucus, slight congestion in the tonsil, mad wheezing, and slight flatulence by abdominal percussion. At this moment, if propel treaUnent is given, the symptolns can be relieved. I treated infantile asthma patients according to flir seizure and remission phases. Now, the report is given as follows.

Research on Acupuncture-moxibustion for Dry Eye Syndrome

Dry eye syndrome （DES） is a commonly encountered ophthalmological disease, with a relatively high incidence, and expects an effective treatment method. Acupunctureoxibustion therapy promotes tear production of lacrimal gland without causing a trauma, and thus has a great advantage in treating DES. Through literature analysis, this article summarized the research progress in both clinical practice and mechanism of acupuncture- moxibustion in treating DES during the recent 10 years, for providing valuable references for the application of acupuncture-moxibustion for DES.

Investigating the influence of moxibustion on colonic mucosal barrier in rats with dextran sulfate sodium-induced ulcerative colitis

Objective:To observe the effect of moxibustion on the colonic mucosal barrier of rats with ulcerative colitis(UC)induced by dextran sulfate sodium(DSS).Methods:Forty male Sprague-Dawley rats were randomly divided into a normal group and a modeling group,with 20 rats in each group.Rats in the modeling group were subjected to preparing experimental UC models by drinking 4%DSS for seven consecutive days.Two modeled rats and two normal rats were randomly selected for model identification.After the success of UC model was confirmed,the remaining 18 modeled rats were randomly divided into three groups,a model group,a model+herbal cake-partitioned moxibustion group,and a model+mild moxibustion group,with six rats in each group;the remaining normal rats were randomly divided into three groups,a normal group,a normal+herbal cake-partitioned moxibustion group,and a normal+mild moxibustion group,with six rats in each group.After 7 d of intervention with the herbal cake-partitioned moxibustion or the mild moxibustion,hematoxylin-eosin(HE)staining technique was used to observe the pathological changes of colon tissue under a light microscope;Western blotting and/or immunohistochemical techniques were used to detect the protein expression levels of Occludin,Claudin,junction adhesion molecular 1(JAM1),mucin 2(MUC2),and transforming growth factor beta1(TGF-β1)in rat colon tissue.Results:Compared with the normal group,the colon tissue was severely damaged,the pathological score was significantly increased,and the protein expression levels of Occludin,Claudin,JAM1,MUC2,and TGF-β1 were significantly decreased in the model group(P<0.01);while there were no significant differences in the colonic histopathological score,protein expression levels of Occludin,Claudin,JAM1,MUC2,and TGF-β1 in the normal+herbal cake-partitioned moxibustion group and the normal+mild moxibustion group(P>0.05).Compared with the model group,the model+herbal cake-partitioned moxibustion group and the model+mild moxibustion group showed repaired colon tissue,ulcer healing,significantly reduced pathological score,and significantly increased protein expression levels of JAM1,MUC2,and TGF-β1(P<0.05);the Occludin protein expression level in the colon tissue of the model+mild moxibustion group was increased(P<0.01).Conclusion:Neither herbal cake-partitioned moxibustion nor mild moxibustion influences the colonic histopathology and intestinal mucosal barrier-related protein expression in the normal rats;both herbal cake-partitioned moxibustion and mild moxibustion can up-regulate the protein expression levels of JAM1,MUC2,and TGF-β1 in the colon tissue of UC rats.Mild moxibustion can up-regulate Occludin protein expression.This may be a mechanism of moxibustion in reducing colonic mucosa inflammation in UC.

Treatment of Tolosa-Hunt Syndrome with Acupuncture:A Case Report

Tolosa-Hunt sldrome is a rue medical condition with special clinical manifestations, characterized by sharp severe headache as the initial symptom. The pain is usually located around fh orbit or deep inside, ocular motor nerve palsy following or together wifll the painH. We treated a case of Tolosa-Hunt syndrome with acupuncture-moxibusfion treatment, and now report it as tollows.