目的:探究节律性听觉注意刺激联合踏车训练对帕金森病患者运动功能的影响。方法:选取我院收治的58例帕金森患者,随机将其分为对照组与观察组,各29例。对照组予以节律性听觉注意刺激进行治疗,观察组在对照组基础上加施踏车训练治疗,两组...目的:探究节律性听觉注意刺激联合踏车训练对帕金森病患者运动功能的影响。方法:选取我院收治的58例帕金森患者,随机将其分为对照组与观察组,各29例。对照组予以节律性听觉注意刺激进行治疗,观察组在对照组基础上加施踏车训练治疗,两组均连续训练3个月。比较两组患者各时间点的运动功能情况及日常生活活动能力评分。结果:训练前,两组UPDRSⅢ评分组间差异无统计学意义( P >0.05);训练后,观察组UPDRSⅢ评分显著低于对照组( P <0.05);同时,训练前及训练1周后,两组日常生活活动能力评分组间差异无统计学意义( P >0.05);训练4周及3个月后,观察组日常生活活动能力评分显著高于对照组( P <0.05)。结论:节律性听觉注意刺激联合踏车训练可显著提高帕金森病患者运动功能,同时可提高患者日常生活能力,值得临床推广。展开更多
One of the most effective techniques in the rehabilitation of visual field defects is based on implementation of oculomotor strategies to compensate for visual field loss. In the present study we develop a new rehabil...One of the most effective techniques in the rehabilitation of visual field defects is based on implementation of oculomotor strategies to compensate for visual field loss. In the present study we develop a new rehabilitation approach based on the audio-visual stimulation of the visual field. Since it has been demonstrated that audio-visual interaction in multisensory neurons can improve temporally visual perception in patients with hemianopia, the aim of the present study was to verify whether a systematic audio-visual stimulation might induce a long-lasting amelioration of visual field disorders. Eight patients with chronic visual field defects were trained to detect the presence of visual targets. During the training, the visual stimulus could be presented alone, i.e. unimodal condition, or together with an acoustic stimulus, i.e. crossmodal conditions. In the crossmodal conditions, the spatial disparity between the visual and the acoustic stimuli were systematically varied (0, 16 and 32°of disparity). Furthermore, the temporal interval between the acoustic stimulus and the visual target in the crossmodal conditions was gradually reduced from 500 to 0 ms. Patients underwent the treatment for 4 h daily, over a period of nearly 2 weeks. The results showed a progressive improvement of visual detections during the training and an improvement of visual oculomotor exploration that allowed patients to efficiently compensate for the loss of vision. More interesting, there was a transfer of treatment gains to functional measures assessing visual field exploration and to daily-life activities, which was found stable at the 1 month follow-up control session. These findings are very promising with respect to the possibility of taking advantage of human multisensory capabilities to recover from unimodal sensory impairments.展开更多
文摘目的:探究节律性听觉注意刺激联合踏车训练对帕金森病患者运动功能的影响。方法:选取我院收治的58例帕金森患者,随机将其分为对照组与观察组,各29例。对照组予以节律性听觉注意刺激进行治疗,观察组在对照组基础上加施踏车训练治疗,两组均连续训练3个月。比较两组患者各时间点的运动功能情况及日常生活活动能力评分。结果:训练前,两组UPDRSⅢ评分组间差异无统计学意义( P >0.05);训练后,观察组UPDRSⅢ评分显著低于对照组( P <0.05);同时,训练前及训练1周后,两组日常生活活动能力评分组间差异无统计学意义( P >0.05);训练4周及3个月后,观察组日常生活活动能力评分显著高于对照组( P <0.05)。结论:节律性听觉注意刺激联合踏车训练可显著提高帕金森病患者运动功能,同时可提高患者日常生活能力,值得临床推广。
文摘One of the most effective techniques in the rehabilitation of visual field defects is based on implementation of oculomotor strategies to compensate for visual field loss. In the present study we develop a new rehabilitation approach based on the audio-visual stimulation of the visual field. Since it has been demonstrated that audio-visual interaction in multisensory neurons can improve temporally visual perception in patients with hemianopia, the aim of the present study was to verify whether a systematic audio-visual stimulation might induce a long-lasting amelioration of visual field disorders. Eight patients with chronic visual field defects were trained to detect the presence of visual targets. During the training, the visual stimulus could be presented alone, i.e. unimodal condition, or together with an acoustic stimulus, i.e. crossmodal conditions. In the crossmodal conditions, the spatial disparity between the visual and the acoustic stimuli were systematically varied (0, 16 and 32°of disparity). Furthermore, the temporal interval between the acoustic stimulus and the visual target in the crossmodal conditions was gradually reduced from 500 to 0 ms. Patients underwent the treatment for 4 h daily, over a period of nearly 2 weeks. The results showed a progressive improvement of visual detections during the training and an improvement of visual oculomotor exploration that allowed patients to efficiently compensate for the loss of vision. More interesting, there was a transfer of treatment gains to functional measures assessing visual field exploration and to daily-life activities, which was found stable at the 1 month follow-up control session. These findings are very promising with respect to the possibility of taking advantage of human multisensory capabilities to recover from unimodal sensory impairments.
