The current study aimed to investigate the chemical components of the Chinese mangrove plant Cerbera manghas L., collected in Hainan Island.Repeated column chromatography was performed for the isolation and purificati...The current study aimed to investigate the chemical components of the Chinese mangrove plant Cerbera manghas L., collected in Hainan Island.Repeated column chromatography was performed for the isolation and purification.Compounds were identified by the analysis of their 1D and 2D NMR data as well as IR and MS spectral data.A new linear monoterpene,named (2E,6S)-8-hydroxy-2-hydroxymethyl-6-rnethyl-2-octenoic acid(1),together with cerbinal(2),cerberidol(3),2α,3β,24-trihydroxyolea- 12en-28oic acid(4),4,4,9,7- tetrahydroxy-3,3 -dimethoxy-7,9-epoxylignan (5), (-)-olovil (6), (+)-cycioolivil (7), naringenin-7-glucoside (8), aromadendrin (9), naringenine (10), and (+)-dihydroquercetin (11) were isolated from the EtOH and CH2Cl2 extracts. Compounds 4, 5, 8-11 were isolated from this plant for the first time.展开更多
基金NSFC(Grant No.30672607)the National 863HiTech Projects(Grant No.2006AA09Z446,2006DFA31100)China Uni-PhD Base Project(Grant No.20060001149).
文摘The current study aimed to investigate the chemical components of the Chinese mangrove plant Cerbera manghas L., collected in Hainan Island.Repeated column chromatography was performed for the isolation and purification.Compounds were identified by the analysis of their 1D and 2D NMR data as well as IR and MS spectral data.A new linear monoterpene,named (2E,6S)-8-hydroxy-2-hydroxymethyl-6-rnethyl-2-octenoic acid(1),together with cerbinal(2),cerberidol(3),2α,3β,24-trihydroxyolea- 12en-28oic acid(4),4,4,9,7- tetrahydroxy-3,3 -dimethoxy-7,9-epoxylignan (5), (-)-olovil (6), (+)-cycioolivil (7), naringenin-7-glucoside (8), aromadendrin (9), naringenine (10), and (+)-dihydroquercetin (11) were isolated from the EtOH and CH2Cl2 extracts. Compounds 4, 5, 8-11 were isolated from this plant for the first time.