基于不断发展的系统级封装技术,提出了一种用于芯片间高速互连的新型可集成的物理器件:硅基毫米波介质填充波导。文中阐述了该器件的物理原理,采用建模、仿真相结合的方法对该模块进行了结构设计,利用新的设计思路结合半导体工艺解决了...基于不断发展的系统级封装技术,提出了一种用于芯片间高速互连的新型可集成的物理器件:硅基毫米波介质填充波导。文中阐述了该器件的物理原理,采用建模、仿真相结合的方法对该模块进行了结构设计,利用新的设计思路结合半导体工艺解决了毫米波互连结构内部的反射、电压驻波比(VSWR)、信号耦合、准TEM-TE-准TEM转换传输问题以及毫米波互连结构阵列中信号泄露的问题,并利用半导体与MEMS加工工艺加以实现。测试结果表明宽度为680μm的单通道矩形波导,-10 d B带宽为9.8 GHz,相对带宽为12.56%;传输损耗为1 d B/cm,工作频带内相邻波导之间串扰低于-40 d B,可以形成大阵列并进行集成,从而实现芯片间数据的并行传输。展开更多
Detecting white spot syndrome virus （WSSV） in shrimp in high efficiency and veracity is important for disease prevention in aquaculture. Antibody-based mieroarray is a novel proteomic technology that can meet the re...Detecting white spot syndrome virus （WSSV） in shrimp in high efficiency and veracity is important for disease prevention in aquaculture. Antibody-based mieroarray is a novel proteomic technology that can meet the requirements. In this study, we developed an antibody microarray for WSSV-detection in a specific and parallel way at multiple samples. First, seven slides each with different modifications were characterized by atomic force microscope, and were compared in the efficiency of immobilizing proteins. Of the seven, 3-dimensional structured agarose gel-modified slides were chosen appropriate for the microarray for having higher signal value and superior spot size. A purified rabbit anti-WSSV antibody was arrayed as the capture antibody of the microarray on the agarose gel-modified slides, and then the mieroarray slides were incubated in the tissue homogenate of sampled shrimp and the antibody-antigen complex was detected by Cy3-conjugated anti-WSSV monoclonal antibody. The results were measured by a laser chipscanner and analyzed with software. To obtain satisfied fluorescence signal intensity, optimal conditions were searched. The detection limit of the antibody microarray for WSSV is 0.62μg/mL, with a woven long shelf life for 6 months at 4℃ or 8 months at -20℃. Furthermore, concordance between antibody microarray and traditional indirect ELISA reached 100% for WSSV detection. These results suggest that the antibody microarray could be served as an effective tool for diagnostic and epidemiological studies of WSSV.展开更多
Application-specific data processing units (DPUs) are commonly adopted for operational control and data processing in space missions. To overcome the limitations of traditional radiation-hardened or fully commercial d...Application-specific data processing units (DPUs) are commonly adopted for operational control and data processing in space missions. To overcome the limitations of traditional radiation-hardened or fully commercial design approaches, a reconfigurable-system-on-chip (RSoC) solution based on state-of-the-art FPGA is introduced. The flexibility and reliability of this approach are outlined, and the requirements for an enhanced RSoC design with in-flight reconfigurability for space applications are presented. This design has been demonstrated as an on-board computer prototype, providing an in-flight reconfigurable DPU design approach using integrated hardwired processors.展开更多
Helper-thread of a task can hide the memory access time of irregular data on the chip muhi-core processor （CMP）. For constructing a compiler that effectively supports the helper-thread of a task in the multi-core sc...Helper-thread of a task can hide the memory access time of irregular data on the chip muhi-core processor （CMP）. For constructing a compiler that effectively supports the helper-thread of a task in the multi-core scenario based on the last level shared cache, this paper studies its performance stable condi- tions. Unfortunately, there is no existing model that allows extensive investigation of the impact of stable conditions, we present the base of pre-computation that is formalized by our degraded task-pair 〈 T, T＇ 〉 with the helper-thread, and its stable conditions are analyzed. Finally, a novel performance model and a constructing method of pre-computation based on our positive degraded task-pair are proposed. The efficient results are shown by our experiments. If we further exploit memory level parallelism （MLP） for our task-pair, the task-pair 〈 T, T＇ 〉 can reach better performance.展开更多
To collect neuronal activity data from awake, freely behaving animals, we developed miniature telemetry recording system. The integrated system consists of four major components： l） Microelectrodes and micro-driver ...To collect neuronal activity data from awake, freely behaving animals, we developed miniature telemetry recording system. The integrated system consists of four major components： l） Microelectrodes and micro-driver assembly, 2） analog front end （AFE）, 3） programmable system on chip （PSoC）, and 4） ra- dio transceiver and the LabVIEW were used as a platform for the graphic user interface. The result showed the system was able to record and analyze neuronal recordings in freely moving animals and lasted continuously for a time period of a week or more. This is very useful for the study of the interdisciplinary research of neu- roscience and information engineering techniques. The circuits and architecture of the devices can be adapted for neurobiology and research with other small animals.展开更多
文摘基于不断发展的系统级封装技术,提出了一种用于芯片间高速互连的新型可集成的物理器件:硅基毫米波介质填充波导。文中阐述了该器件的物理原理,采用建模、仿真相结合的方法对该模块进行了结构设计,利用新的设计思路结合半导体工艺解决了毫米波互连结构内部的反射、电压驻波比(VSWR)、信号耦合、准TEM-TE-准TEM转换传输问题以及毫米波互连结构阵列中信号泄露的问题,并利用半导体与MEMS加工工艺加以实现。测试结果表明宽度为680μm的单通道矩形波导,-10 d B带宽为9.8 GHz,相对带宽为12.56%;传输损耗为1 d B/cm,工作频带内相邻波导之间串扰低于-40 d B,可以形成大阵列并进行集成,从而实现芯片间数据的并行传输。
基金Supported by the National High Technology Research and Development Program of China (863 Program) (No. 2006AA100306)Special Fund for Agro-Scientific Research in the Public Interest (No. 201103034)
文摘Detecting white spot syndrome virus （WSSV） in shrimp in high efficiency and veracity is important for disease prevention in aquaculture. Antibody-based mieroarray is a novel proteomic technology that can meet the requirements. In this study, we developed an antibody microarray for WSSV-detection in a specific and parallel way at multiple samples. First, seven slides each with different modifications were characterized by atomic force microscope, and were compared in the efficiency of immobilizing proteins. Of the seven, 3-dimensional structured agarose gel-modified slides were chosen appropriate for the microarray for having higher signal value and superior spot size. A purified rabbit anti-WSSV antibody was arrayed as the capture antibody of the microarray on the agarose gel-modified slides, and then the mieroarray slides were incubated in the tissue homogenate of sampled shrimp and the antibody-antigen complex was detected by Cy3-conjugated anti-WSSV monoclonal antibody. The results were measured by a laser chipscanner and analyzed with software. To obtain satisfied fluorescence signal intensity, optimal conditions were searched. The detection limit of the antibody microarray for WSSV is 0.62μg/mL, with a woven long shelf life for 6 months at 4℃ or 8 months at -20℃. Furthermore, concordance between antibody microarray and traditional indirect ELISA reached 100% for WSSV detection. These results suggest that the antibody microarray could be served as an effective tool for diagnostic and epidemiological studies of WSSV.
基金Supported by Innovative Program of the Chinese Academy of Sciences (No. KGCY-SYW-407-02)Grand International Cooperation Foundation of Shanghai Science and Technology Commission (No. 052207046)
文摘Application-specific data processing units (DPUs) are commonly adopted for operational control and data processing in space missions. To overcome the limitations of traditional radiation-hardened or fully commercial design approaches, a reconfigurable-system-on-chip (RSoC) solution based on state-of-the-art FPGA is introduced. The flexibility and reliability of this approach are outlined, and the requirements for an enhanced RSoC design with in-flight reconfigurability for space applications are presented. This design has been demonstrated as an on-board computer prototype, providing an in-flight reconfigurable DPU design approach using integrated hardwired processors.
文摘Helper-thread of a task can hide the memory access time of irregular data on the chip muhi-core processor （CMP）. For constructing a compiler that effectively supports the helper-thread of a task in the multi-core scenario based on the last level shared cache, this paper studies its performance stable condi- tions. Unfortunately, there is no existing model that allows extensive investigation of the impact of stable conditions, we present the base of pre-computation that is formalized by our degraded task-pair 〈 T, T＇ 〉 with the helper-thread, and its stable conditions are analyzed. Finally, a novel performance model and a constructing method of pre-computation based on our positive degraded task-pair are proposed. The efficient results are shown by our experiments. If we further exploit memory level parallelism （MLP） for our task-pair, the task-pair 〈 T, T＇ 〉 can reach better performance.
基金supported by the Shandong Province Nature Science Foundation(Grant No.ZR2010CM055)Science Development Plan Project(Grant No.2010GGX10133)
文摘To collect neuronal activity data from awake, freely behaving animals, we developed miniature telemetry recording system. The integrated system consists of four major components： l） Microelectrodes and micro-driver assembly, 2） analog front end （AFE）, 3） programmable system on chip （PSoC）, and 4） ra- dio transceiver and the LabVIEW were used as a platform for the graphic user interface. The result showed the system was able to record and analyze neuronal recordings in freely moving animals and lasted continuously for a time period of a week or more. This is very useful for the study of the interdisciplinary research of neu- roscience and information engineering techniques. The circuits and architecture of the devices can be adapted for neurobiology and research with other small animals.
