Aim To investigate the chemical constituents of the unripe fruits of Evodia rutaecarpa （Juss.） Benth. and provide a scientific basis for its quality control. Methods The compounds were isolated by silica gel column ...Aim To investigate the chemical constituents of the unripe fruits of Evodia rutaecarpa （Juss.） Benth. and provide a scientific basis for its quality control. Methods The compounds were isolated by silica gel column chromatography and identified by spectral analysis. Results Sixteen compounds were identified as evodiamine （1）, rutaecarpine （2）, β-sitosterol （3）, isorhamnetin（4）, evodol （5）, quercetin （6）, limonin （7）, wuzhuyurutine A （8）, evodirutaenin （9）, shihulimonin A （10）, wuzhuyurutine B（ll）, wuchuyuamide Ⅰ （12）, daucosterol （13）, trans-caffeic acid methylate （14）, dehydroevodiamine （15）and sucrose （16）. Conclusion Compounds 4, 6, 10 and 14 were isolated from the title plant for the first time.展开更多
Ruta genus is a member of the family Rutaceae that has been cultivated widely in many regions of the world because of its medicinal properties. In Tessala Mountain （Sidi Bel Abbes Country, North-Western of Algeria）,...Ruta genus is a member of the family Rutaceae that has been cultivated widely in many regions of the world because of its medicinal properties. In Tessala Mountain （Sidi Bel Abbes Country, North-Western of Algeria）, the Ruta genus commonly known by ＂fidjel＂ is represented by two species： Ruta Chalepensis L. and Ruta Montana （L.） L. frequently used by local population in a traditional treatment. The water-distilled essential oils from this species yielded 7.23% and 6.104% for Ruta chalepensis L. and Ruta montana （L.） L. respectively. The essential oil of Ruta montana （L.） L. showed a strong antibacterial activity against all bacterial strains tested （Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853, Mycobacterium kansasii ATCC ! 2478 and Mycobacterium vaccae ATCC 1548314） compared to Ruta chalepensis L. oils which have a moderate effect only on Staphylococcus aureus ATCC 25923 and Pseudomonas aeruginosa ATCC 27853. Therefor, the antibacterial properties of the essential oils of Ruta Chalepensis L. and Ruta Montana （L.） L. are now well established through this study and therefore could justify their future uses in the treatment of nosocomial infections.展开更多
基金The National High-Tech 863 Project (No.2002AA22Z343C)Beijing Sciences Foundation (No.Z0004105040311).
文摘Aim To investigate the chemical constituents of the unripe fruits of Evodia rutaecarpa （Juss.） Benth. and provide a scientific basis for its quality control. Methods The compounds were isolated by silica gel column chromatography and identified by spectral analysis. Results Sixteen compounds were identified as evodiamine （1）, rutaecarpine （2）, β-sitosterol （3）, isorhamnetin（4）, evodol （5）, quercetin （6）, limonin （7）, wuzhuyurutine A （8）, evodirutaenin （9）, shihulimonin A （10）, wuzhuyurutine B（ll）, wuchuyuamide Ⅰ （12）, daucosterol （13）, trans-caffeic acid methylate （14）, dehydroevodiamine （15）and sucrose （16）. Conclusion Compounds 4, 6, 10 and 14 were isolated from the title plant for the first time.
文摘Ruta genus is a member of the family Rutaceae that has been cultivated widely in many regions of the world because of its medicinal properties. In Tessala Mountain （Sidi Bel Abbes Country, North-Western of Algeria）, the Ruta genus commonly known by ＂fidjel＂ is represented by two species： Ruta Chalepensis L. and Ruta Montana （L.） L. frequently used by local population in a traditional treatment. The water-distilled essential oils from this species yielded 7.23% and 6.104% for Ruta chalepensis L. and Ruta montana （L.） L. respectively. The essential oil of Ruta montana （L.） L. showed a strong antibacterial activity against all bacterial strains tested （Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853, Mycobacterium kansasii ATCC ! 2478 and Mycobacterium vaccae ATCC 1548314） compared to Ruta chalepensis L. oils which have a moderate effect only on Staphylococcus aureus ATCC 25923 and Pseudomonas aeruginosa ATCC 27853. Therefor, the antibacterial properties of the essential oils of Ruta Chalepensis L. and Ruta Montana （L.） L. are now well established through this study and therefore could justify their future uses in the treatment of nosocomial infections.
