Hypertonic saline resuscitation reduces apoptosis of intestinal mucosa in a rat model of hemorrhagic shock

Objective: To investigate the early effects of hypertonic and isotonic saline solutions on apoptosis of intestinal mucosa in rats with hemorrhagic shock. Methods: A model of rat with severe hemorrhagic shock was established in 21 Sprague-Dawley (SD) rats. The rats were randomly divided into the sham group, normal saline resuscitation (NS) group, and hypertonic saline resuscitation (HTS) group, with 7 in each group. We detected and compared the apoptosis in small intestinal mucosa of rats after hemorrhagic shock and resuscitation by terminal deoxynucleotidyl transferase dUTP nick end labelling (TUNEL), FITC (fluo- rescein-iso-thiocyanate)-Annexin V/PI (propidium iodide) double staining method, and flow cytometry. Results: In the early stage of hemorrhagic shock and resuscitation, marked apoptosis of small intestinal mucosa in the rats of both NS and HTS groups was observed. The numbers of apoptotic cells in these two groups were significantly greater than that in the sham group (P<0.01). In the HTS group, the apoptic cells significantly decreased, compared with the NS group (P<0.01). Conclusion: In this rat model of severe hemorrhagic shock, the HTS resuscitation of small volume is more effective than the NS resuscitation in reducing apoptosis of intestinal mucosa in rats, which may improve the prognosis of trauma.

Measurement and Correlation on Liquid DifFusion Coefficients of Aqueous L-Threonine Solutions from 298.15K to 328.15 K

The diffusion coefficients of aqueous L-threonine solutions were determined from 298.15 K to 328.15 K by the metallic diaphragm cell method with accuracy, promptness and convenience. Meanwhile, the densities and viscosities of the solutions were also determined and correlated. Based on a semi-empirical model for correlating the diffusion coefficients of some amino acids in their aqueous solutions, a new semi-empirical model for correlating the diffusion coefficients involving temperature was provided, which is more comprehensive and less experiment dependent compared to the previous model. The fitting results are satisfactory. Compared to a former model for correlating the diffusion coefficients of solid organic salts in their aqueous solutions, this model provides significant improvement in correlation of diffusion coefficients with different temperatures avoiding arduous work.

Three-Dimensional Water Quality Model Based on FVCOM for Total Load Control Management in Guan River Estuary,Northern Jiangsu Province

Guan River Estuary and adjacent coastal area(GREC) suffer from serious pollution and eutrophicational problems over the recent years.Thus,reducing the land-based load through the national pollutant total load control program and developing hydrodynamic and water quality models that can simulate the complex circulation and water quality kinetics within the system,including longitudinal and lateral variations in nutrient and COD concentrations,is a matter of urgency.In this study,a three-dimensional,hydrodynamic,water quality model was developed in GREC,Northern Jiangsu Province.The complex three-dimensional hydrodynamics of GREC were modeled using the unstructured-grid,finite-volume,free-surface,primitive equation coastal ocean circulation model(FVCOM).The water quality model was adapted from the mesocosm nutrients dynamic model in the south Yellow Sea and considers eight compartments:dissolved inorganic nitrogen,soluble reactive phosphorus(SRP),phytoplankton,zooplankton,detritus,dissolved organic nitrogen(DON),dissolved organic phosphorus(DOP),and chemical oxygen demand.The hydrodynamic and water quality models were calibrated and confirmed for 2012 and 2013.A comparison of the model simulations with extensive dataset shows that the models accurately simulate the longitudinal distribution of the hydrodynamics and water quality.The model can be used for total load control management to improve water quality in this area.

Effect of Different Shading Practices Used at Pre-harvest Stage on Quality and Storage Life of Sultana Seedless Grapes

Covering the grapevine rows to delay maturity and thus the harvest date becomes a widespread practice at Sultana seedless vineyards. The research work was carried out with different covers to examine their effects on grape quality and storage life in 2009 and 2010. Grapevines were covered with three different densities （shading ratios： 35%, 55%, 75%） at the veraison period. Unshaded （0%） control grapevines and grapevines shaded under different ratios were covered with polypropylene cross-stitch just before harvest maturity. Grapes under cover were harvested nearly one month after than those maturing under open conditions. Grape clusters were packed in PE bags and pre-cooled after harvest and then SO2-generating pads has been put on top, bags were sealed. In the second year at the 120th day of the storage, decay development has been observed in all applications. Total soluble solids content, maturity index and a＊ colour value were found lower in 55% and 75% shaded grapes compared to unshaded grapevines. Still, berry removal force and hue angle value in 55% and 75% of shaded grapes were higher than unshaded grapes. Effects of shading ratios on these parameters decrease or disappear at the end of storage.

礼仪教育需自儿时始

出差回来,遇到一位朋友。见面伊始,就夸我的儿子讲文明,懂礼貌。我倒有些丈二和尚摸不着头脑。细听原委,才知道,是我外出期间,朋友曾来过电话,刚好是我的儿子接的他说:『当令公子告诉我「家母不在家」之后,又问我「贵姓」,以及有没有事情需要转告,并「请」我留下地址和电话……』听到此,我慌忙摆手,连称『过奖』,请他切莫恭维,并提醒他,犬子已经一十有五,照古典小说的习惯提法,已接近『二八』了呢!

是你选择了这个世界

我们对未来有多期许,对现在就有多失望。两年前,我曾为《花火》写过一篇专栏,题名《投我桃李,报之琼瑶》,曾获不少嘉许。文中这样写道:"你愤怒敌对,世界以愤怒敌对报你。你阳光温和,世界以阳光温和报你。你所看到的世界,是你希望呈现的样子。理解和尊重,是这世间最高贵的情意。"彼时的我,阳光温和地呼吁大家要"心怀感恩",而内心深处,未尝不对我们的时代感到有些失望。直到今年发生的一件事,才彻底改变了我的想法。花苏榕,《因为是医生》真人秀节目中的七位"小主"之一。他能从一众精英中脱颖而出,除了金灿灿、华丽丽的履历表。