桃李依旧笑春风

在山峦叠嶂、群峰耸翠，地处赣西北边陲的铜鼓县幽居乡，人们都记着黄孝哉的名字。黄孝哉，一个极其普通的山村教师，却在这个寂静的山乡产生了不平凡的反响。虽然，他离开自己所毕生热爱的教育战线已经五个多年头了，但是，他的精神却永远留在幽居人民的记忆里……

老人再婚有约定 遗产继承化纷争

7年前,砀山县周寨镇居民老范的老伴去世,经人介绍老范与同为丧偶的女士朱某相识,二人相处几个月后打算结婚。老范在周寨镇街上有两间门面房,为避免将来就遗产继承发生纠纷,两位老人婚前达成了一份＂身后互不继承遗产＂的协议。2014年年底,老范因病去世,

县一级如何抓好联合督查

为适应督查工作重点的转移,县级应特别注重横向联系,着力搞好联合督查,发挥督查网络的整体功能.一、联合督查的程序建立必要的工作程序是实行科学管理的重要手段之一.我室与县政府督查室密切配合,共同探索联合督查的新路子,形成了《联合督查工作程序》.首先,党政协调,准确立项.(1)按照党政序列,各自吃透会议、文件精神。

Isozyme Analysis on the Populations of Ruditapes philippinarum

Horizontal starch gel electrophoresis was used to investigate the genetic structure of six populations of Ruditapes philippinarum in the coast of China. Seven enzymes revealed eleven putative loci, and seven of them were polymorphic, PGM^＊, MDH-1^ ＊, MDH-3^＊, LAP-1^＊, LAP-2^＊, MPI-1^＊ and MPI-2^＊. The proportions of polymorphic loci of R. philippinarum populations varied from 0.454 5 to 0.636 4. The values of observed and expected heterozygosities were from 0.039 4 to 0.154 5 and from 0.111 1 to 0.238 5, respectively. Nei＇s genetic distance varied from 0.003 3 to 0.025 3 with an average of 0.013 5. It is suggested that the genetic diversity of R. philippinarum was high.

Targeted therapy of gastric cancer:current and prospective strategies

Gastric cancer is the third leading cause of cancer-related death worldwide. Surgery is currently the only curative treatment strategy. Chemotherapy has shown limited efficacy in advanced gastric cancer patients with a median overall survival of less than one year. Thus, new treatments are urgently needed. Trastuzumab and Ramucirumab are the only targeted therapies approved currently. Most Phase Ⅲ clinical trials evaluating targeted drugs in gastric cancer have failed. This review will evaluate relevant clinical trials with targeted therapies performed in gastric cancer patients, discuss the possible reasons for the failure, and indicate new possibilities to enhance gastric cancer treatment.

Specifying and Configuring Routing Policies of Relative AS in RPSL

Routing policies specification language (RPSL) allows a network operator to specify routing policies at various levels in the Internet hierarchy, for example at the autonomous system (AS) level. At the same time, policies can be specified with sufficient detail in RPSL so that the low level router configurations can be generated from them. This paper is a discussion on using the RPSL to describe routing policies of relative AS in the Internet routing registry (IRR). We first analyze the relationships between a pair of ASes, and then explain how to specify various relative AS routing policies in RPSL. At last, we show an example of configuring routing policies using RtConfig that is a tool developed by the Routing Arbiter Project (RAP).

Empirical Test of Determinants of Accepting Mobile Payment

From a global perspective, the develop ment of 3G services in China is quite different from other countries. The factors that influence users＇ adoption of mobile payment are worth ex ploring. This study employs the Technology Ac ceptance Model （TAM） to examine determinant factors affecting consumers＇ acceptance intentions of mobile payment. We adopt Hofstede＇s cultural dimensions as moderators to extend the TAM model for exploring the impact of uncertainty a voidance on mobile payment acceptance.

Inclusive Intergenerational Experiences With Elderly and Minor People： A New Horizon for Inclusion？

The research presents the progressive increase of lifelong education and its influence on the paradigm of socio-educational inclusion. Today＇s society is characterized by its increasing aspiration and demand for activities of social promotion and personal development, that is, activities that tend to reinforce the social fabric in its human and community values, in the elimination of loneliness, or increasing the quality of life, through the full enjoyment of civic rights, common cultural property, or participation in the opportunities offered by public and community life The older population has transformed their habits, integrating new values generated by social changes. In turn, it leads to possible changes in social intervention. These include training, leisure, tourism, social skills development, the use of the Internet as a tool for knowledge and communication, and social participation. These new social behaviors can be an opportunity to build a more cohesive and supportive society, without generational breaches And this line, the attention to diversity and its even processes seeks to expand its reach, generating intergenerational spaces

Phase Equilibrium of Isobutanol in Supercritical CO2

Vapor-liquid phase equilibrium data including composition,densities,molar volume and equilibrium constant of isobutanol in supercritical carbon dioxide from 313.2K to 353.2K were measured in a variable-volume visual cell.The properties of critical point were obtained by extrapolation.The results showed that critical temperature,critical pressure and critical compressibility factor of CO2-isobutanol system decreased with the increase of critical CO2 content.The phase equilibrium model was established by Peng-Robinson equation of state and van der Waals-2 mixing regulation,and model parameters were determined by optimization calculation of nonlinear least square method.The correlation between calculated values and the experimental data showed good agreement.

Numerical Prediction of Added Resistance and Vertical Ship Motions in Regular Head Waves

The numerical prediction of added resistance and vertical ship motions of one ITTC （Intemational Towing Tank Conference） S-175 containership in regular head waves by our own in-house unsteady RANS solver naoe-FOAM-SJTU is presented in this paper. The development of the solver naoe-FOAM-SJTU is based on the open source CFD tool, OpenFOAM. Numerical analysis is focused on the added resistance and vertical ship motions （heave and pitch motions） with four very different wavelengths （ 0.8Lpp 〈 2 〈 1.5L ） in regular head waves. Once the wavelength is near the length of the ship model, the responses of the resistance and ship motions become strongly influenced by nonlinear factors, as a result difficulties within simulations occur. In the paper, a comparison of the experimental results and the nonlinear strip theory was reviewed and based on the findings, the RANS simulations by the solver naoe-FOAM-SJTU were considered competent with the prediction of added resistance and vertical ship motions in a wide range of wave lengths.

Analyzing Influencing Factors of Rural Poverty in Typical Poverty Areas of Hainan Province: A Case Study of Lingao County

Rural poverty and poverty reduction are not only the focal issues that have attracted worldwide attention, but also the vital issues on people's livelihood that has attached great importance and aimed to be solved by the central and local governments of China. Based on the survey data of 354 farming households, this paper, taking the national poverty county of Lingao County, Hainan Province for an example, examined the characteristics of rural poverty of the county. Moreover, this paper established the spatial lag model(SLM) from five dimensions, namely, status of the household head, household structure, health status, income composition and traffic accessibility, to analyze the main influencing factors of rural poverty according to the values of Moran's I and the diagnosis of spatial dependence of the OLS model. It is found that the poor farming households gathered mainly in five towns in the north and southwest of the county, and the rural poverty have the characteristics of low educational level of the heads, more minor children, high population of farming peasants, high incidence of disease and low proportion of household wage-equivalent income. The results also showed that the variables such as the number of minor children, the number of migrant worker, the number of farming peasants and the proportion of wage-equivalent income have significant effectiveness on rural poverty, while the status of the household head, health status and traffic accessibility have little influence. It is an important way to realize the goal of poverty alleviation by controlling the number of farmers' fertility, strengthening the vocational skills training of farmers, vigorously developing specialization and large-scale agriculture and increasing the employment opportunities of farmers.

Physical contributors to glenohumeral internal rotation deficit in high school baseball players

Background： Glenohumeral internal rotation deficit （GIRD） is a risk factor for shoulder and elbow injury in baseball players. Although this evidence forms a basis for recommending stretching, clinical measures of internal rotation range of motion （ROM） do not differentiate if GIRD is due to muscular, capsuloligamentous, or osseous factors. Understanding the contributions of these structures to GIRD is important for the development of targeted interventions. We hypothesize that the osseous component will have the greatest relative contribution to GIRD, followed by muscle stiffness and posterior capsule thickness. Methods： Internal rotation ROM, muscle stiffness （teres minor, infraspinatus, and posterior deltoid）, posterior capsule thickness, and humeral retrotorsion were evaluated on 156 baseball players. A side-to-side difference was calculated for each variable. Variables were entered into a multivariable linear regression to determine the significant predictors of GIRD. Results： The regression model was statistically significant （R2 = 0.134, F（1, 156） = 24.0, p 〈 0.01） with only humeral retrotorsion difference remaining as a significant predictor （β = -0.243, t156 = -4.9, p 〈 0.01）. A greater humeral retrotorsion side-to-side difference was associated with more GIRD. Conclusion： Humeral retrotorsion accounted for 13.3% of the variance in GIRD. The stiffness of the superficial shoulder muscles and capsular thickness, as measured in this study, were not predictors of GIRD. Factors not assessed in this study, such as deeper muscle stiffness, capsule/ ligament laxity, and neuromuscular regulation of muscle stiffness may also contribute to GIRD. Since it is the largest contributor to GIRD, causes of changes in humeral retrotorsion need to be identified. The osseous component only accounted for 13.3% of the variance in GIRD, indicating a large contribution from soft tissues factors that were not addressed in this study. These factors need to be identified to develop evidence-based evaluations and intervention programs to decrease the risk of injury in baseball players.

Freshwater Cyanophages

Cyanophages are double-stranded DNA viruses that infect cyanobacteria, and they can be found in both freshwater and marine environments. They have a complex pattem of host ranges and play important roles in controlling cyanobacteria population. Unlike marine cyanophages, for which there have been a number of recent investigations, very little attention has been paid to freshwater cyanophages. This review summarizes the taxonomy and morphology, host range, distribution, seasonal dynamics, and complete genomes of freshwater cyanophages, as well as diagnostic markers that can be used to identify them.

Internal Whistle-Blowing Intentions： A Study of Demographic and Individual Factors

Internal auditors hold a unique position in their organizations to prevent, deter, and detect corporate wrongdoings. However, the role of this profession in investigating their ethical decision-making behaviors towards internal whistle-blowing intentions has been very often neglected. Furthermore, although extensive researches have been undertaken on the issue of whistle blowing globally, empirical studies on this area are still scarce in Malaysia. This paper examines internal whistle-blowing intentions among internal auditors in Malaysia by utilizing three independent vignettes. A mail survey was conducted to investigate demographic and individual factors that could influence internal auditors＇ ethical decision-making processes. The likelihood for internal whistle-blowing intentions was significant among internal auditors＇ ethical judgments for all the three vignettes. Demographic factors （gender, age, and tenure） and other individual factors （locus of control and organizational commitment） failed to explain the likelihood of internal auditors＇ internal whistle-blowing intentions. Findings should aid researchers in their understandings of the determinants of individuals＇ internal whistle-blowing behaviors.

Systemic treatment in EGFR-ALK NSCLC patients:second line therapy and beyond

Lung cancer is the most frequently diagnosed cancer and a leading cause of cancer mortality worldwide, with adenocarcinoma being the most common histological subtype. Deeper understanding of the pathobiology of non-small cell lung cancer(NSCLC) has led to the development of small molecules that target genetic mutations known to play critical roles in progression to metastatic disease and to influence response to targeted therapies. The principle goal of precision medicine is to define those patient populations most likely to respond to targeted therapies. However, the cancer genome landscape is composed of relatively few "mountains" [representing the most commonly mutated genes like KRAS, epidermal growth factor(EGFR), and anaplastic lymphoma kinase(ALK)] and a vast number of "hills"(representing low frequency but potentially actionable mutations). Low-frequency lesions that affect a druggable gene product allow a relatively small population of cancer patients for targeted therapy to be selected.

Seasonal variations in the phytoplankton community and the relationship between environmental factors of the sea around Xiaoheishan Island in China

Seasonal variations in the phytoplankton community and the relationship between environmental factors of the sea area around Xiaoheishan Island are investigated in the present study. Xiaoheishan Island is located at 37°58′14″N and 120°38′46″E in Shandong Province, China. A total of 65 species of phytoplankton belonging to three phyla and 27 genera were identified, with Bacillariophyta having the largest number of species. The annual average chlorophyll a concentration for this area was 3.11 μg/L, and there occurs a Skeletonema costatum bloom in winter. The Shannon-Weaver indexes(log_2) of the phytoplankton from all stations were higher than 1, and the Pielou indexes were all higher than 0.3. The results of the canonical correspondence analysis(CCA) indicated that water temperature, PO_4^(3ˉ) and Cu were the environmental factors that had the greatest influence on the distribution of the phytoplankton community throughout the entire year. Although the concentration of heavy metal is well up to the state standards of the first grade of China(GB 3097-1997), these metals still have an impact on the phytoplankton community from this area.

Role of ATG16L,NOD2 and IL23R in Crohn's disease pathogenesis

Inflammatory bowel disease is a group of diseases that includes Crohn＇s disease （CD） and ulcerative colitis. CD is characterized as a chronic inflammatory disease of the gastrointestinal tract, ranging from the mouth to the anus. Although there are gross pathological and histological similarities between CD and Johne＇s dis- ease of cattle, the cause of CD remains controversial. It is vital to understand fully the cause of this disease because it affects approximately 500 000 people in North America and Europe. It ranges from 27 to 48 cases per 100 000 people. There are many theories on the cause of CD ranging from possible association with environmental factors including microorganisms to imbalance in the intestinal normal flora of the pa- tients. Regardless of the environmental trigger, there is strong evidence that a genetic disposition is a major key in acquiring CD. Many studies have proven the link between mutations in the ATG16L, NOD2/CARD15, IBDS, CTLA4, TNFSF15 and IL23R genes, and CD. The purpose of this review is to examine all genetic aspects and theories of CD, including up to date multiple popu- lation studies performed worldwide.

The risk analysis and prevention on the pro-poverty-tourism category BOT project

BOT is a new investment and financing model to find favor with many countries because of its own characteristics and advantages. The paper takes analysis on its characteristics and the main risk factors of the Chinese pro-poverty-tourism category BOT project based on the projects related to the domestic and international risk management, and gives some relevant preventive measures.

Sexual Ethics; A Need Indeed, Buddhist Ethics as a Model

According to Psychological theories of motivation, sexuality is a biological need which urges to satisfy sexual desire. Though it is not essential for the survival of an individual, it plays a major role in the growth, development, adjustment and well-being. Therefore, sexuality is a common aspect in the existence and it should not be neglected. However, in many religious ethical issues, sexuality had been treated negatively and identified as a barrier for an advanced spiritual life. Even in tribal societies there were some sexual taboos that controlled man＇s sexual behavior to some extent. Among religious ethical codes, one may find that it had been placed an important position for controlling or completely eliminating sexual behaviors. In modem world, what is evident is that this so called sexual need has been used for many commercial and marketing purposes. Even in advertising field, sexual desire of man is used as a mean of attracting public. Phonograph has become a very profitable illegal professional today. Sexual medicines, drugs and tools are available everywhere in the society. Though sexual education had been included into the curriculum in schools and higher education institutions, the awareness of sexuality among people seems to be in a low level. While biologically man is compelled to fulfill sexual desire internally, it is motivated externally by many social factors. So that not only misconceptions of sexuality, but also misbehaviors of sexuality can be observed in the society today. By examining these current situations of man＇s sexual behaviors, there is a big need to formulate a sexual ethical code--a code of law with the help of religious teachings. Otherwise these various sexual behaviors may create more and more social and world problems. In this paper, my aim is to examine Buddhist ethics in order to formulate a sexual ethical code.