OBJECTIVE： To investigate the potential rules and knowledge of Traditional Chinese Medicine （TCM） and Western Medicine （WM） treatment on chronic urticaria （CU） based on data-mining methods. METHODS： Sixty pati...OBJECTIVE： To investigate the potential rules and knowledge of Traditional Chinese Medicine （TCM） and Western Medicine （WM） treatment on chronic urticaria （CU） based on data-mining methods. METHODS： Sixty patients with chronic urticaria, treated with TCM and WM, were selected. Gray correlation analyses were adopted to determine therapeutic efficacy. Association algorithms were utilized to ascertain the correlation between the disease course and treatment results. A genetic algorithm was applied to discover the optimization model in theTCM and WM treatment on CU. RESULTS： The total symptom scores after 4 weeks and 8 weeks of treatment in the TCM spleen-strengthening group correlated highly with the pretreatment total symptom score. The duration of treatment showed the greatest impact on the total symptom score. A quartic equation was established （y= - 1.6403x 10 - 6x4＋0.00025576x3＋0.0012819 x2 - 1.024x＋79.5879, and x=106.9518, y=83.0036） using the genetic algorithm. CONCLUSION： TCM treatment had a better effect in the later stage, whereas WM was better in the early stage. The duration of disease course had an impact on the effects of treatment. If the average total symptom score before treatment was 〈 83.0036, TCM or WM treatment could achieve better efficacy.展开更多
Objective: To observe the clinical effect of comprehensive acupuncture therapy for chronic urticaria. Methods: A total of 70 patients with chronic urticaria were treated with acupuncture, bloodletting after pricking a...Objective: To observe the clinical effect of comprehensive acupuncture therapy for chronic urticaria. Methods: A total of 70 patients with chronic urticaria were treated with acupuncture, bloodletting after pricking and cupping [on Shenque (CV 8)]. The changes of signs and symptoms were observed before and after treatment. The therapeutic efficacy was then assessed according to the change rate of clinical symptoms scoring. Results: After treatment, 11 of the 70 cases got basic recovery, 21 cases got marked effectiveness, 27 cases got improvement and 11 cases got no effect. The total effective rate was 84.3%. There was statistical significance in symptoms score between before and after treatment (P<0.01). Conclusion: Combining acupuncture, bloodletting after pricking and cupping on Shenque (CV 8) is effective for chronic urticaria.展开更多
To learn the current research status of acupuncture-moxibustion in treating chronic urticaria, the relevant clinical reports indexed by CNKI and VlP databases during 2000 and 2012 were retrieved, and then summarized a...To learn the current research status of acupuncture-moxibustion in treating chronic urticaria, the relevant clinical reports indexed by CNKI and VlP databases during 2000 and 2012 were retrieved, and then summarized and analyzed from the aspects of treatment method, acupoint selection, medicine, treatment frequency, and criteria of therapeutic efficacy, for guiding the treatment of chronic urticaria with acupuncture-moxibustion. The results show that acupuncture-moxibustion therapy has stable therapeutic efficacy in treating chronic urticaria with low adverse reaction rate, but the current evaluation criteria are too subiective to cluantifv.展开更多
Objective:To observe the clinical efficacy of acupuncture in treatment of chronic urticaria and the change in the content of serum immunoglobulin E(IgE),and to discuss the effect of acupuncture on the imbalance of T h...Objective:To observe the clinical efficacy of acupuncture in treatment of chronic urticaria and the change in the content of serum immunoglobulin E(IgE),and to discuss the effect of acupuncture on the imbalance of T helper(Th)1/Th2 cell function via observing the changes in the contents of interferon-y(IFN-y)and interleukin-4(IL-4).Methods:Ninety patients meeting the inclusion criteria of chronic urticaria were randomized into an acupuncture-medication group,an acupuncture group and a Western medication group by the random number table method.The acupuncture-medication group was intervened by acupuncture,cupping,collateral-pricking bloodletting and oral administration of cetirizine hydrochloride tablets;the acupuncture group was treated with acupuncture,cupping and collateral-pricking bloodletting;the Western medication group only received oral administration of cetirizine hydrochloride tablets.Before treatment and after 6-week treatment,the changes in the symptom scores and the contents of serum IgE,IFN-γ and IL-4 in the three groups were observed.Results:There were no significant differences in the total effective rate among the three groups(all P>0.05),but the cured and markedly effective rate was significantly higher in the acupuncture-medication group than that in the Western medication group(P<0.05).After treatment,the total symptom score decreased in the three groups(P<0.05),and the improvement of total symptom score in the acupuncture-medication group was more significant than that in the Western medication group(P<0.05).The component symptom scores all decreased after treatment in the three groups(all P<0.05);the improvements of the scores of itch intensity,and skin lesion size and number were more significant in the acupuncture-medication group than in the Western medication group(all P<0.05);the improvement of the skin lesion size score was more significant in the acupuncture group than in the Western medication group(P<0.01).The contents of IgE and IL-4 dropped(all P<0.05)and the content of IFN-y increased(P<0.05)after treatment in the three groups;the post-treatment changes in the serum contents of IgE and IFN-y were more significant in the acupuncture-medication group than in the Western medication group(both P<0.05).The incidence rate of adverse reactions was significantly lower in the acupuncture-medication group and acupuncture group than in the Western medication group(both P<0.05),and the relapse rate was significantly lower in the acupuncture-medication group than in the Western medication group(P<0.05).Conclusion:Combined acupuncture and medication can enhance the cured and markedly effective rate in treating chronic urticaria.Acupuncture is equivalent to cetirizine hydrochloride tablets comparing the clinical efficacy in treatment of chronic urticaria.Acupuncture plus medication and acupuncture alone both can effectively mitigate the clinical symptoms,with low incidence of adverse reactions.The relapse rate is low when using acupuncture together with medication.Acupuncture plus medication can work better in regulating the contents of IgE and IFN-y and improving the imbalance of Th1/Th2 cell function.展开更多
文摘OBJECTIVE： To investigate the potential rules and knowledge of Traditional Chinese Medicine （TCM） and Western Medicine （WM） treatment on chronic urticaria （CU） based on data-mining methods. METHODS： Sixty patients with chronic urticaria, treated with TCM and WM, were selected. Gray correlation analyses were adopted to determine therapeutic efficacy. Association algorithms were utilized to ascertain the correlation between the disease course and treatment results. A genetic algorithm was applied to discover the optimization model in theTCM and WM treatment on CU. RESULTS： The total symptom scores after 4 weeks and 8 weeks of treatment in the TCM spleen-strengthening group correlated highly with the pretreatment total symptom score. The duration of treatment showed the greatest impact on the total symptom score. A quartic equation was established （y= - 1.6403x 10 - 6x4＋0.00025576x3＋0.0012819 x2 - 1.024x＋79.5879, and x=106.9518, y=83.0036） using the genetic algorithm. CONCLUSION： TCM treatment had a better effect in the later stage, whereas WM was better in the early stage. The duration of disease course had an impact on the effects of treatment. If the average total symptom score before treatment was 〈 83.0036, TCM or WM treatment could achieve better efficacy.
基金supported by the General Program of Department of Scientific Research and Education,Shanghai Municipal Health Bureau (20124046)
文摘Objective: To observe the clinical effect of comprehensive acupuncture therapy for chronic urticaria. Methods: A total of 70 patients with chronic urticaria were treated with acupuncture, bloodletting after pricking and cupping [on Shenque (CV 8)]. The changes of signs and symptoms were observed before and after treatment. The therapeutic efficacy was then assessed according to the change rate of clinical symptoms scoring. Results: After treatment, 11 of the 70 cases got basic recovery, 21 cases got marked effectiveness, 27 cases got improvement and 11 cases got no effect. The total effective rate was 84.3%. There was statistical significance in symptoms score between before and after treatment (P<0.01). Conclusion: Combining acupuncture, bloodletting after pricking and cupping on Shenque (CV 8) is effective for chronic urticaria.
基金supported by Scientific Research Project of Shanghai Health Bureau(20124046)
文摘To learn the current research status of acupuncture-moxibustion in treating chronic urticaria, the relevant clinical reports indexed by CNKI and VlP databases during 2000 and 2012 were retrieved, and then summarized and analyzed from the aspects of treatment method, acupoint selection, medicine, treatment frequency, and criteria of therapeutic efficacy, for guiding the treatment of chronic urticaria with acupuncture-moxibustion. The results show that acupuncture-moxibustion therapy has stable therapeutic efficacy in treating chronic urticaria with low adverse reaction rate, but the current evaluation criteria are too subiective to cluantifv.
文摘Objective:To observe the clinical efficacy of acupuncture in treatment of chronic urticaria and the change in the content of serum immunoglobulin E(IgE),and to discuss the effect of acupuncture on the imbalance of T helper(Th)1/Th2 cell function via observing the changes in the contents of interferon-y(IFN-y)and interleukin-4(IL-4).Methods:Ninety patients meeting the inclusion criteria of chronic urticaria were randomized into an acupuncture-medication group,an acupuncture group and a Western medication group by the random number table method.The acupuncture-medication group was intervened by acupuncture,cupping,collateral-pricking bloodletting and oral administration of cetirizine hydrochloride tablets;the acupuncture group was treated with acupuncture,cupping and collateral-pricking bloodletting;the Western medication group only received oral administration of cetirizine hydrochloride tablets.Before treatment and after 6-week treatment,the changes in the symptom scores and the contents of serum IgE,IFN-γ and IL-4 in the three groups were observed.Results:There were no significant differences in the total effective rate among the three groups(all P>0.05),but the cured and markedly effective rate was significantly higher in the acupuncture-medication group than that in the Western medication group(P<0.05).After treatment,the total symptom score decreased in the three groups(P<0.05),and the improvement of total symptom score in the acupuncture-medication group was more significant than that in the Western medication group(P<0.05).The component symptom scores all decreased after treatment in the three groups(all P<0.05);the improvements of the scores of itch intensity,and skin lesion size and number were more significant in the acupuncture-medication group than in the Western medication group(all P<0.05);the improvement of the skin lesion size score was more significant in the acupuncture group than in the Western medication group(P<0.01).The contents of IgE and IL-4 dropped(all P<0.05)and the content of IFN-y increased(P<0.05)after treatment in the three groups;the post-treatment changes in the serum contents of IgE and IFN-y were more significant in the acupuncture-medication group than in the Western medication group(both P<0.05).The incidence rate of adverse reactions was significantly lower in the acupuncture-medication group and acupuncture group than in the Western medication group(both P<0.05),and the relapse rate was significantly lower in the acupuncture-medication group than in the Western medication group(P<0.05).Conclusion:Combined acupuncture and medication can enhance the cured and markedly effective rate in treating chronic urticaria.Acupuncture is equivalent to cetirizine hydrochloride tablets comparing the clinical efficacy in treatment of chronic urticaria.Acupuncture plus medication and acupuncture alone both can effectively mitigate the clinical symptoms,with low incidence of adverse reactions.The relapse rate is low when using acupuncture together with medication.Acupuncture plus medication can work better in regulating the contents of IgE and IFN-y and improving the imbalance of Th1/Th2 cell function.
