Freeze drying or lyophilization of aqueous solutions is widely used in pharmaceutical industry. The in-creased importance Of the process is gaining a worldwide interest of research. A growing body of literature has de...Freeze drying or lyophilization of aqueous solutions is widely used in pharmaceutical industry. The in-creased importance Of the process is gaining a worldwide interest of research. A growing body of literature has demonstrated that the scientific approach can result in improved product quality with minimum trial and error em-piricism. Formulation and process development need a systematical understanding of the physical chemistry of freezing and freeze drying, material science and mechanisms of heat and mass transfer. This paper presents an overview on freeze ding of aqueous solutions based on publications in the past few decades. The important issuesof the process are analyzed.展开更多
The taxonomic status of the medicinal plants in Jordan is expressed in terms of its diversity, the documentation of the scientific research that is carried out locally over the last many years; to test for the potenti...The taxonomic status of the medicinal plants in Jordan is expressed in terms of its diversity, the documentation of the scientific research that is carried out locally over the last many years; to test for the potential of some medicinal plant species (MPS) in Jordan on different biological aspects is also prepared. This has been reported here by revising and documenting the available literature to the author on this subject. The ecological status of medicinal plants in Jordar is also pointed out. The aim of this research was mainly to evaluate the status of the research on medicinal plants that was carried oul: to test for the different biological potentials of medicinal plants in Jordan and to emphasis the richness of the country of its wild medicinal plants, which are of promising value in whether for use in traditional medicine or in pharmaceutical industry, and certainly need lots of investigations and scientific research. Photographs of some medicinal plants that are common in Jordan and are used in traditional medicine in the urban areas and the Badia region, which is located in the Eastern part of the country and characterized by its dry weather conditions and least amount of rainfall in the country, are also included; the plant photographs are selected from different representative families of the common flowering plants in Jordan.展开更多
This work, through an empirical research (Jayaram, Kannan and Tan model), aims at analysing, at the same time, the effect of "structural mechanisms" and "relationships building" factors on the value creation pro...This work, through an empirical research (Jayaram, Kannan and Tan model), aims at analysing, at the same time, the effect of "structural mechanisms" and "relationships building" factors on the value creation process in the Supply Chain. The two factors have been chosen among others, as they have been considered able to improve the internal and external processes of the firm and the Supply Chain, and in consequence, able to influence the value creation process of the Supply Chain Management. The research has been directed to the chemical and pharmaceutical sector of the Southern Lazio (Italy) and a factorial analysis, using the software SPSS (16.0) which has been performed in order to verify the influence of these factors in value creation process of the Supply Chain The outcomes confirm the positive contribute in the value creation process for companies that take care of the relationships among the stakeholders in the management process of the supply chain (the "relationships building" factor) and, in parallel with the analysis of the same process, the secondary role of the "structural mechanisms" factor has been highlighted.展开更多
This paper is a result of a review through 25 papers on the synthesis of three-, four-, five-, six-, and seven-membered rings on solid support. Solid-phase organic synthesis methods that enable the rapid production of...This paper is a result of a review through 25 papers on the synthesis of three-, four-, five-, six-, and seven-membered rings on solid support. Solid-phase organic synthesis methods that enable the rapid production of arrays of heterocycles are of critical importance to the pharmaceutical industry. The generation of heterocyclic chemistry by solid-phase synthesis will definitely accelerate the development of pharmaceutical research.展开更多
基金Supported by the National Natural Science Foundation of China(21076042)Research Grants Council of Hong Kong SAR (RGC 600704)
文摘Freeze drying or lyophilization of aqueous solutions is widely used in pharmaceutical industry. The in-creased importance Of the process is gaining a worldwide interest of research. A growing body of literature has demonstrated that the scientific approach can result in improved product quality with minimum trial and error em-piricism. Formulation and process development need a systematical understanding of the physical chemistry of freezing and freeze drying, material science and mechanisms of heat and mass transfer. This paper presents an overview on freeze ding of aqueous solutions based on publications in the past few decades. The important issuesof the process are analyzed.
文摘The taxonomic status of the medicinal plants in Jordan is expressed in terms of its diversity, the documentation of the scientific research that is carried out locally over the last many years; to test for the potential of some medicinal plant species (MPS) in Jordan on different biological aspects is also prepared. This has been reported here by revising and documenting the available literature to the author on this subject. The ecological status of medicinal plants in Jordar is also pointed out. The aim of this research was mainly to evaluate the status of the research on medicinal plants that was carried oul: to test for the different biological potentials of medicinal plants in Jordan and to emphasis the richness of the country of its wild medicinal plants, which are of promising value in whether for use in traditional medicine or in pharmaceutical industry, and certainly need lots of investigations and scientific research. Photographs of some medicinal plants that are common in Jordan and are used in traditional medicine in the urban areas and the Badia region, which is located in the Eastern part of the country and characterized by its dry weather conditions and least amount of rainfall in the country, are also included; the plant photographs are selected from different representative families of the common flowering plants in Jordan.
文摘This work, through an empirical research (Jayaram, Kannan and Tan model), aims at analysing, at the same time, the effect of "structural mechanisms" and "relationships building" factors on the value creation process in the Supply Chain. The two factors have been chosen among others, as they have been considered able to improve the internal and external processes of the firm and the Supply Chain, and in consequence, able to influence the value creation process of the Supply Chain Management. The research has been directed to the chemical and pharmaceutical sector of the Southern Lazio (Italy) and a factorial analysis, using the software SPSS (16.0) which has been performed in order to verify the influence of these factors in value creation process of the Supply Chain The outcomes confirm the positive contribute in the value creation process for companies that take care of the relationships among the stakeholders in the management process of the supply chain (the "relationships building" factor) and, in parallel with the analysis of the same process, the secondary role of the "structural mechanisms" factor has been highlighted.
文摘This paper is a result of a review through 25 papers on the synthesis of three-, four-, five-, six-, and seven-membered rings on solid support. Solid-phase organic synthesis methods that enable the rapid production of arrays of heterocycles are of critical importance to the pharmaceutical industry. The generation of heterocyclic chemistry by solid-phase synthesis will definitely accelerate the development of pharmaceutical research.