黄檗药材林培育技术

本文论述了黄檗的播种育苗技术及造林技术,以满足黄檗在医药市场的需求。并对黄檗今后的研究方向提出了建议。

穿心莲野生品与栽培品质量比较研究

目的:对资源调查采集到的穿心莲野生品与栽培品进行质量比较。方法:采用性状鉴别、药材含叶量、HPLC等方法进行含量测定。结果:穿心莲野生品符合《中国药典》相关要求,可做药用;广西产野生品叶片大、含叶量高、有效成分含量高,质量优于栽培品。结论:应对宝贵的穿心莲野生资源加以保护和利用,本实验对穿心莲良种选育、GAP规范化种植基地选址有一定指导意义。

硫熏蒸山楂药材的安全使用研究

硫熏药材历史悠久,有利于药材的加工贮藏,但熏硫药材SO_2含量过高会对人体产生严重危害。在熏硫药材的安全使用方面,如何保证降低SO_2含量的同时不太影响其有效成分含量是研究热点。以硫熏蒸的山楂中药材为研究对象,以酸碱滴定法测定其中SO_2的残留量,和山楂中枸橼酸的含量。试验结果表明,随水浸泡处理时间的增长,山楂中SO_2的含量会逐渐降低并最终趋于稳定,且山楂浸泡1小时左右,其SO_2含量为149 ug/g、枸橼酸的含量为5.11%,山楂中药材符合《药典》规定。结论:清水浸泡可有效脱除硫熏中药材中的SO_2,且有效成分损失不大,仍具有药用价值。

Qualitative and Quantitative Analysis of Rhizoma of Polygonum cuspidatum

Aim To establish reliable methods for evaluating the quality of rhizoma of Polygonum cuspidatum( Huzhang in Chinese). Methods TLC and HPLC were employed for the chemical identification and content determination,respectively. Results A qualitative TLC method and a quantitative HPLC method with piceid as the reference substance were established, respectively. With piceid as the reference substance and ethyl acetate-methanol-formic acid-water ( 19:3:0.5:1) as the mobile phase, a TLC method for the identification of Huzhang from the commonly used crude drugs of the same family was also set up. Conclusion The established TLC method can reasonably appraise the quality of the drug and easily distinguish Huzhang from the other commonly used crude drugs of the same family. The HPLC method for determining piceid is simple, reproducible, accurate, and feasible.

Investigation on influencing factors of 5-HMF content in Schisandra

In order to investigate the influencing factors of 5-hydroxymethyl-2-furaldehyde （5-HMF） content in Schisandra, confirm the theory of 5-HMF deriving mainly from Schisandra processing course, and give some suggestions about the Schisandra processing method, the 5-HMF contents in decoctions of Schisandra under different heating temperature, decocting time, soaking time, processing methods and treatment with different solvents before decocting the Schisandra were measured by RP-HPLC method. The results showed that there is great difference of 5-HMF level in decoctions from differently processed Schisandra and unprocessed Schisandra; decocting time of 60 rain has some effects on 5-HMF level in decoctions and there is certain quantity 5-HMF in processed Schisandra itself and very little 5-HMF in unprocessed Schisandra. Heating time, heating temperature and treating solvents all have effect on 5-HMF level in decoction of Schisandra. 5-HMF in Schisandra was mainly from processing course. Both long heating time and high heating temperature can increase 5-HMF level in Schisandra. The production of 5-HMF in Schisandra may have some relationships with some polar components, which can dissolve in water, ethanol and acetone, especially in ethanol. To control processing temperature, processing time and treatment with some solvent is very important for controlling 5-HMF level in Schisandra.

Economic analysis in product design——A case study of a TCM dietary supplement

An approach for the economic analysis of chemical product design is proposed. It takes into account of customers' preference on product quality and economic considerations such as pricing, profit, market share, capital investment, and operating cost. The activities needed to support business decision making – identifying product quality, estimating product cost, calculating financial metrics, and performing make–buy analysis – are discussed.The design of a Ganoderma lucidum dietary supplement, a traditional Chinese medicinal(TCM) product, is used to illustrate all the activities in this approach.

Issues in Freeze Drying of Aqueous Solutions

Freeze drying or lyophilization of aqueous solutions is widely used in pharmaceutical industry. The in-creased importance Of the process is gaining a worldwide interest of research. A growing body of literature has demonstrated that the scientific approach can result in improved product quality with minimum trial and error em-piricism. Formulation and process development need a systematical understanding of the physical chemistry of freezing and freeze drying, material science and mechanisms of heat and mass transfer. This paper presents an overview on freeze ding of aqueous solutions based on publications in the past few decades. The important issuesof the process are analyzed.

Development of Hong Kong Chinese Materia Medica(HKCMM) standards

The development of HKCMM standards is one of the achievements of developing Hong Kong into an intemational centre for Chinese medicine. In order to enable more people concerned to have an intimate knowledge of this standard, the author was invited to introduce the development of HKCMM standards to readers, including： 1） the history of the project and the basis for legislative supports; 2） the composition and operation of the regulatory division, the research institution and the evaluation committee; 3） the progress of HKCMM standards; 4） the contents and features of HKCMM standards.

Oxalate contents of commonly used Chinese medicinal herbs

OBJECTIVE:To assess the total and soluble oxalate contents of commonly used Chinese medicinal herbs.METHODS:Twenty-two Chinese medicinal herbs were extracted in both acid and water prior to determination of total and soluble oxalate,respectively.Oxalate was assayed in herbal extracts using a well-established enzymatic procedure.RESULTS:Among the 22 medicinal herbs,there was significant variation in oxalate content;Houttuynia cordata contained the highest amount of soluble oxalate(2146 mg/100 g) and Selaginella doederleinii contained the lowest amount(71 mg/100g).CONCLUSION:The results indicated that different Chinese medicinal herbs,even from the same family,contain significantly different amounts of oxalate.In susceptible individuals,the use of medicinal herbs with the highest oxalate contents could increase risk of kidney stone formation.