In this short review we summarize the different strategies for discovery and development of antiviral agents, including targeting virus entry into host, virus replication within cells, infant virus assembly and releas...In this short review we summarize the different strategies for discovery and development of antiviral agents, including targeting virus entry into host, virus replication within cells, infant virus assembly and release from the infected cells. The progress on development of various classes of antivirus agents and their potential in virus therapy, mainly targeting human immunodeficiency virus (HIV), was also discussed.展开更多
基金National Basic Research Program of China(973 Program,Grant No.2010CB-12300)National Natural Science Foundation of China(Grant No.20932001 and 20852001)"985"Project Foundation(Grant No.985-2-126-121)
文摘In this short review we summarize the different strategies for discovery and development of antiviral agents, including targeting virus entry into host, virus replication within cells, infant virus assembly and release from the infected cells. The progress on development of various classes of antivirus agents and their potential in virus therapy, mainly targeting human immunodeficiency virus (HIV), was also discussed.