目的:探讨TBL(Team Based Learning)教学法在中职药物化学教学中的效果。方法:将广东省新兴中药学校2014B级药剂专业241名学生按照组内异质、组间同质的原则分为实验组和对照组。实验组采用TBL教学法,对照组采用传统教学法,课后进行考...目的:探讨TBL(Team Based Learning)教学法在中职药物化学教学中的效果。方法:将广东省新兴中药学校2014B级药剂专业241名学生按照组内异质、组间同质的原则分为实验组和对照组。实验组采用TBL教学法,对照组采用传统教学法,课后进行考核。结果:大多数学生对TBL教学法满意。实验组考试成绩得分高于对照组。结论:TBL教学法应用在中职药物化学教学,效果优于传统模式,值得推广。展开更多
The aim of this study was to establish a method for discriminating Dendrobium officinale from four of its close relatives Den- drobium chrysanthum, Dendrobium erystallinum, Dendrobium aphyllum and Dendrobium devonianu...The aim of this study was to establish a method for discriminating Dendrobium officinale from four of its close relatives Den- drobium chrysanthum, Dendrobium erystallinum, Dendrobium aphyllum and Dendrobium devonianum based on chemical composition analysis. We analyzed 62 samples of 24 Dendrobium species. High performance liquid chromatography analysis confirmed that the four low molecular weight compounds 4',5,7-trihydroxyflavanone (naringenin), 3,4-dihydroxy-4',5-dime- tboxybibenzyl (DDB^2), 3',4-dihydroxy-3,5'-dimethoxybibenzyl (gigantol), and 4,4'-dihydroxy-3,3',5-trimethoxybibenzyl (moscatilin), were common in the genus. The phenol-sulfuric acid method was used to quantify polysaccharides, and the mon- osaccharide composition of the polysaccharides was determined by gas chromatography. Stepwise discriminant analysis was used to differentiate among the five closely related species based on the chemical composition analysis. This proved to be a simple and accurate approach for discriminating among these species. The results also showed that the polysaccharide content, the amounts of the four low molecular weight compounds, and the mannose to glucose ratio, were important factors for species discriminaut. Therefore, we propose that a chemical analysis based on quantification of naringenin, bibenzyl, and polysaccha- rides is effective for identifying D. officinale.展开更多
文摘目的:探讨TBL(Team Based Learning)教学法在中职药物化学教学中的效果。方法:将广东省新兴中药学校2014B级药剂专业241名学生按照组内异质、组间同质的原则分为实验组和对照组。实验组采用TBL教学法,对照组采用传统教学法,课后进行考核。结果:大多数学生对TBL教学法满意。实验组考试成绩得分高于对照组。结论:TBL教学法应用在中职药物化学教学,效果优于传统模式,值得推广。
基金supported by the National Natural Science Foundation of China (Grant Nos. 30830117 and 31170016) the Major Scientific and Technological Special Project for Significant New Drugs Creation (Grant No. 2012ZX09301002-001-031)
文摘The aim of this study was to establish a method for discriminating Dendrobium officinale from four of its close relatives Den- drobium chrysanthum, Dendrobium erystallinum, Dendrobium aphyllum and Dendrobium devonianum based on chemical composition analysis. We analyzed 62 samples of 24 Dendrobium species. High performance liquid chromatography analysis confirmed that the four low molecular weight compounds 4',5,7-trihydroxyflavanone (naringenin), 3,4-dihydroxy-4',5-dime- tboxybibenzyl (DDB^2), 3',4-dihydroxy-3,5'-dimethoxybibenzyl (gigantol), and 4,4'-dihydroxy-3,3',5-trimethoxybibenzyl (moscatilin), were common in the genus. The phenol-sulfuric acid method was used to quantify polysaccharides, and the mon- osaccharide composition of the polysaccharides was determined by gas chromatography. Stepwise discriminant analysis was used to differentiate among the five closely related species based on the chemical composition analysis. This proved to be a simple and accurate approach for discriminating among these species. The results also showed that the polysaccharide content, the amounts of the four low molecular weight compounds, and the mannose to glucose ratio, were important factors for species discriminaut. Therefore, we propose that a chemical analysis based on quantification of naringenin, bibenzyl, and polysaccha- rides is effective for identifying D. officinale.