Benzoxaborole,as a versatile scaffold,plays important roles in organic synthesis,molecular recognition and supramolecular chemistry.It is also a privileged structure in medicinal chemistry due to its desirable physico...Benzoxaborole,as a versatile scaffold,plays important roles in organic synthesis,molecular recognition and supramolecular chemistry.It is also a privileged structure in medicinal chemistry due to its desirable physicochemical and drug-like properties.Recently,benzoxaboroles were widely applied as antifungal,antibacterial,antiviral,anti-parasite,and anti-inflammatory agents.This review covers the properties,synthetic methods and applications of benzoxaboroles in medicinal chemistry.展开更多
基金supported by National Natural Science Foundatoin of China(81222042)National Basic Research Program of China(2009CB918404,2012CB518001)
文摘Benzoxaborole,as a versatile scaffold,plays important roles in organic synthesis,molecular recognition and supramolecular chemistry.It is also a privileged structure in medicinal chemistry due to its desirable physicochemical and drug-like properties.Recently,benzoxaboroles were widely applied as antifungal,antibacterial,antiviral,anti-parasite,and anti-inflammatory agents.This review covers the properties,synthetic methods and applications of benzoxaboroles in medicinal chemistry.
