Nine lignans were isolated and purified by silica gel, ODS, Sephadex LH-20 column chromatographies, preparative HPLC and recrystallization from the aerial parts ofArtemisia absinthium L., and identified as follows： d...Nine lignans were isolated and purified by silica gel, ODS, Sephadex LH-20 column chromatographies, preparative HPLC and recrystallization from the aerial parts ofArtemisia absinthium L., and identified as follows： diayangambin （1）, sesartemin （2）, epiyangambin （3）, （＋）arborone （4）, （-）syringaresinol （5）, epiashchantin （6）, caruilignan C （7）, 7β-caruilignan C （8）, yangambin （9）. Compounds 4, 5, 7, 8 were isolated from this plant for the first time.展开更多
Chemical constituents of the leaves of Artemisia argyi were investigated. By using a variety of chromatographic techniques and spectroscopic methods, six compounds were isolated and identified as follows： clemaphenol...Chemical constituents of the leaves of Artemisia argyi were investigated. By using a variety of chromatographic techniques and spectroscopic methods, six compounds were isolated and identified as follows： clemaphenol A （1）, aurantiamide acetate （2）, camelliagenin A （3）, japonica acid （4）, labd-13（E）-ene-8α,15-diol （5）, and 313-acetoxy-20-oxo-21-nordammaran-23-oic acid （6）. Among these products, compounds 1 and 3-6 were obtained from the genus Artemisia for the first time and compound 2 was firstly reported from the species. Additionally, compound 5 displayed an inhibitory effect against the lipopolysaccharide （LPS）-induced nitric oxide （NO） production in BV-2 microglial cells with an IC50 value of 6.68 μM.展开更多
基金National Natural Science Foundation of China (Grant No. 30973629)
文摘Nine lignans were isolated and purified by silica gel, ODS, Sephadex LH-20 column chromatographies, preparative HPLC and recrystallization from the aerial parts ofArtemisia absinthium L., and identified as follows： diayangambin （1）, sesartemin （2）, epiyangambin （3）, （＋）arborone （4）, （-）syringaresinol （5）, epiashchantin （6）, caruilignan C （7）, 7β-caruilignan C （8）, yangambin （9）. Compounds 4, 5, 7, 8 were isolated from this plant for the first time.
基金National Natural Science Foundation of China(Grant No. 30973629)
文摘Chemical constituents of the leaves of Artemisia argyi were investigated. By using a variety of chromatographic techniques and spectroscopic methods, six compounds were isolated and identified as follows： clemaphenol A （1）, aurantiamide acetate （2）, camelliagenin A （3）, japonica acid （4）, labd-13（E）-ene-8α,15-diol （5）, and 313-acetoxy-20-oxo-21-nordammaran-23-oic acid （6）. Among these products, compounds 1 and 3-6 were obtained from the genus Artemisia for the first time and compound 2 was firstly reported from the species. Additionally, compound 5 displayed an inhibitory effect against the lipopolysaccharide （LPS）-induced nitric oxide （NO） production in BV-2 microglial cells with an IC50 value of 6.68 μM.
