The current concern with the environment promotes the development of new technologies for production with use of alternative materials, from renewable resources, and changes in production processes, having as main obj...The current concern with the environment promotes the development of new technologies for production with use of alternative materials, from renewable resources, and changes in production processes, having as main objective the reduction of environmental impact. One of the alternatives for cleaner production is the use of castor oil derivatives instead of non-renewable sources, such as adhesives based on PVA （polyvinyl acetate）, applied in the manufacturing process of glued laminated bamboo. Based on the versatility of the bamboo laminate and the castor oil, and from the perspective of sustainability, this study aims to contribute to the application of new materials and processes, used in the manufacturing industry, by proposing the use of the polyurethane adhesive based on castor oil for glued laminated bamboo manufacturing, which can later be used in the manufacture of several products. To verify the applicability of the polyurethane adhesive based on castor oil in the glued laminated bamboo manufacture, mechanical tests of traction and shearing of the glue sheet were performed in specimens of the said material, and the results were compared with the Cascorez 2590 and Waterbond adhesives. The results showed that the polyurethane adhesive based on castor oil, in the traction test, has superior performance than the Waterbond adhesive and slightly below than the Cascorez 2590 adhesive, but in the shear test, the polyurethane adhesive based on castor oil presented a slightly inferior performance than the other two adhesives used in the comparison.展开更多
We report a functionalisation strategy which is able to generate Ricinus communis agglutinin 1 （RCA 120） modified PMMA microfluidic device for binding and culturing living cells. The functionalisation is achieved by...We report a functionalisation strategy which is able to generate Ricinus communis agglutinin 1 （RCA 120） modified PMMA microfluidic device for binding and culturing living cells. The functionalisation is achieved by standard aminealdehyde （Schiff base） reaction through the crosslinker, glutaraldehyde. To prove the ability of the RCA 120 modified PMMA surface, the PC 12 cell line （rat pheochromocytoma ceils） has been captured and cultured by the microfluidic device. In the presence of tunicamycin, the dose/timedependence on decreasing of binding affinity of RCA 120 modified device with PC 12 cell is also observed. The experimental results demonstrate that the lectin-functionalized microfluidic device can be employed as efficient cell culturing platform, and has a great promise of being used as a powerful tool for monitoring the interaction of drug with living cell.展开更多
文摘The current concern with the environment promotes the development of new technologies for production with use of alternative materials, from renewable resources, and changes in production processes, having as main objective the reduction of environmental impact. One of the alternatives for cleaner production is the use of castor oil derivatives instead of non-renewable sources, such as adhesives based on PVA （polyvinyl acetate）, applied in the manufacturing process of glued laminated bamboo. Based on the versatility of the bamboo laminate and the castor oil, and from the perspective of sustainability, this study aims to contribute to the application of new materials and processes, used in the manufacturing industry, by proposing the use of the polyurethane adhesive based on castor oil for glued laminated bamboo manufacturing, which can later be used in the manufacture of several products. To verify the applicability of the polyurethane adhesive based on castor oil in the glued laminated bamboo manufacture, mechanical tests of traction and shearing of the glue sheet were performed in specimens of the said material, and the results were compared with the Cascorez 2590 and Waterbond adhesives. The results showed that the polyurethane adhesive based on castor oil, in the traction test, has superior performance than the Waterbond adhesive and slightly below than the Cascorez 2590 adhesive, but in the shear test, the polyurethane adhesive based on castor oil presented a slightly inferior performance than the other two adhesives used in the comparison.
基金supported by National Basic Research Program of China (2011CB935800)the Jilin Provincial Science and Technology Department (20100701)
文摘We report a functionalisation strategy which is able to generate Ricinus communis agglutinin 1 （RCA 120） modified PMMA microfluidic device for binding and culturing living cells. The functionalisation is achieved by standard aminealdehyde （Schiff base） reaction through the crosslinker, glutaraldehyde. To prove the ability of the RCA 120 modified PMMA surface, the PC 12 cell line （rat pheochromocytoma ceils） has been captured and cultured by the microfluidic device. In the presence of tunicamycin, the dose/timedependence on decreasing of binding affinity of RCA 120 modified device with PC 12 cell is also observed. The experimental results demonstrate that the lectin-functionalized microfluidic device can be employed as efficient cell culturing platform, and has a great promise of being used as a powerful tool for monitoring the interaction of drug with living cell.
