The growing number of people suffering from depression has become a social problem in Japan. The problems associated with depression in Japan have been influenced by the pharmaceuticalization of mental health. Since s...The growing number of people suffering from depression has become a social problem in Japan. The problems associated with depression in Japan have been influenced by the pharmaceuticalization of mental health. Since selective serotonin reuptake inhibitors were introduced to Japan＇s pharmaceutical market in 1999, demand for anti-depressant medications has rapidly expanded. It seems likely then that the efforts of pharmaceutical companies, as part of their marketing strategies, to increase people＇s awareness of mental illness have led people who are not actually depressed to have medical consultations and drug treatments for it. This phenomenon is known as ＂disease mongering＂ and has been reported on. Problems exist from the medical perspective also and include the following： expansion of the diagnostic criteria for depression as formulated in the American Psychiatric Association＇s Diagnostic and Statistical Manual of Mental Disorders; treatments that rely heavily on drugs; and biomedicalization. Another reason for the increase in medical consultations is the declining function of communal bodies. This has resulted in individuals struggling psychologically, for example, with anxiety, worry, and depression. In summary, this sociological research analyzed the problems of depression in ｜apan and revealed how the pharmaceuticalization of mental health accelerates the individualization of social problem.展开更多
We evaluated the frequency and category distribution of drug therapy problems in young and elderly patients. A retro- spective study of the medical conditions, drug therapies, and drug therapy problems identified in 1...We evaluated the frequency and category distribution of drug therapy problems in young and elderly patients. A retro- spective study of the medical conditions, drug therapies, and drug therapy problems identified in 102 patients was performed. The patients were divided into young patient group （〈65 years of age） and elderly patient group （〉~ 65 years of age） in a hospital pharmacy setting. Inclusion criteria： patients who were referred by the treating doctors and received evaluation by the clinical pharmacists. Exclusion criteria： patients who were unable to or refused to be evaluated by the clinical pharmacists. We found that 1） Patients in young and elderly groups had a mean of 3 and 5 medical conditions per person, respectively （P = 0.001）. 2） On the average, they took 4 and 7 drug therapies per person, respectively. The elderly patients took a significantly higher number of drug therapies （P = 0.001）. 3） Totally 85 drug therapy problems in 7 categories were identified within 102 patients. 4） 36.8% of young patients experienced 1 to 4 drug therapy problems whereas 61.8% of elderly patient experienced I to 5 drug therapy problems. Drug therapy problems were significantly more prevalent in elderly patients （P = 0.017）. 5） The drug therapy problem by category had similar distribution in young and elderly patients. The elderly patients in this study encountered more drug therapy problems than young patients. Accordingly, more attention should be paid to elderly patients in pharmaceutical care practice.展开更多
It is challenging to characterize the drug-related problems(DRPs)of patients treated by Integrated Traditional Chinese and Western Medicine(ITCWM),both locally and globally.In the present study,we aimed to assess DRPs...It is challenging to characterize the drug-related problems(DRPs)of patients treated by Integrated Traditional Chinese and Western Medicine(ITCWM),both locally and globally.In the present study,we aimed to assess DRPs and factors associated with their occurrence among inpatients of the ITCWM department in China.We retrospectively examined medication use in the ITCWM department,documented in Intelligent Management System Software for Critical Rational Administration of Drug.Various types of DRPs classification were performed based on the Pharmaceutical Care Network Europe(PCNE)classification tool V9.0,and associations of patient’s characteristics were analyzed.A total of 1606 DRPs were identified in 687 inpatients in this study.Problems and causes of DRPs,intervention,acceptance,and outcome of that were classified.PPI(21.7%),endogenous supplements(15.4%),and traditional Chinese medicine(8.7%)contributed to the significant proportion of drug categories associated with DRPs.Approximately half of the patients(47.6%)had at least one DRP.The top four categories of causes were“drug administered via the wrong route”(18.4%),“inappropriate combination”(16.7%),“too long duration of the treatment”(13.0%),and“inappropriate drug form”(12.1%).Total 63.6%of intervention was accepted and fully implemented.“EPP”and“hospital stay days≥10 d”characteristics were most likely to be significantly associated with DRPs.As a necessary review item,DRP was highly performed among inpatients of the ITCWM department.The work provided a benchmark for this population through the PCNE strategy.展开更多
文摘The growing number of people suffering from depression has become a social problem in Japan. The problems associated with depression in Japan have been influenced by the pharmaceuticalization of mental health. Since selective serotonin reuptake inhibitors were introduced to Japan＇s pharmaceutical market in 1999, demand for anti-depressant medications has rapidly expanded. It seems likely then that the efforts of pharmaceutical companies, as part of their marketing strategies, to increase people＇s awareness of mental illness have led people who are not actually depressed to have medical consultations and drug treatments for it. This phenomenon is known as ＂disease mongering＂ and has been reported on. Problems exist from the medical perspective also and include the following： expansion of the diagnostic criteria for depression as formulated in the American Psychiatric Association＇s Diagnostic and Statistical Manual of Mental Disorders; treatments that rely heavily on drugs; and biomedicalization. Another reason for the increase in medical consultations is the declining function of communal bodies. This has resulted in individuals struggling psychologically, for example, with anxiety, worry, and depression. In summary, this sociological research analyzed the problems of depression in ｜apan and revealed how the pharmaceuticalization of mental health accelerates the individualization of social problem.
文摘We evaluated the frequency and category distribution of drug therapy problems in young and elderly patients. A retro- spective study of the medical conditions, drug therapies, and drug therapy problems identified in 102 patients was performed. The patients were divided into young patient group （〈65 years of age） and elderly patient group （〉~ 65 years of age） in a hospital pharmacy setting. Inclusion criteria： patients who were referred by the treating doctors and received evaluation by the clinical pharmacists. Exclusion criteria： patients who were unable to or refused to be evaluated by the clinical pharmacists. We found that 1） Patients in young and elderly groups had a mean of 3 and 5 medical conditions per person, respectively （P = 0.001）. 2） On the average, they took 4 and 7 drug therapies per person, respectively. The elderly patients took a significantly higher number of drug therapies （P = 0.001）. 3） Totally 85 drug therapy problems in 7 categories were identified within 102 patients. 4） 36.8% of young patients experienced 1 to 4 drug therapy problems whereas 61.8% of elderly patient experienced I to 5 drug therapy problems. Drug therapy problems were significantly more prevalent in elderly patients （P = 0.017）. 5） The drug therapy problem by category had similar distribution in young and elderly patients. The elderly patients in this study encountered more drug therapy problems than young patients. Accordingly, more attention should be paid to elderly patients in pharmaceutical care practice.
基金National Major New Drug Creation Project of China(Grant No.2020ZX09201-009)。
文摘It is challenging to characterize the drug-related problems(DRPs)of patients treated by Integrated Traditional Chinese and Western Medicine(ITCWM),both locally and globally.In the present study,we aimed to assess DRPs and factors associated with their occurrence among inpatients of the ITCWM department in China.We retrospectively examined medication use in the ITCWM department,documented in Intelligent Management System Software for Critical Rational Administration of Drug.Various types of DRPs classification were performed based on the Pharmaceutical Care Network Europe(PCNE)classification tool V9.0,and associations of patient’s characteristics were analyzed.A total of 1606 DRPs were identified in 687 inpatients in this study.Problems and causes of DRPs,intervention,acceptance,and outcome of that were classified.PPI(21.7%),endogenous supplements(15.4%),and traditional Chinese medicine(8.7%)contributed to the significant proportion of drug categories associated with DRPs.Approximately half of the patients(47.6%)had at least one DRP.The top four categories of causes were“drug administered via the wrong route”(18.4%),“inappropriate combination”(16.7%),“too long duration of the treatment”(13.0%),and“inappropriate drug form”(12.1%).Total 63.6%of intervention was accepted and fully implemented.“EPP”and“hospital stay days≥10 d”characteristics were most likely to be significantly associated with DRPs.As a necessary review item,DRP was highly performed among inpatients of the ITCWM department.The work provided a benchmark for this population through the PCNE strategy.
