We used genetic algorithm to construct pseudoreceptor site models and made use of the high correlation between interaction energy, which was between the models and the ligands,and bioactivity data of known molecules t...We used genetic algorithm to construct pseudoreceptor site models and made use of the high correlation between interaction energy, which was between the models and the ligands,and bioactivity data of known molecules to predict the bioactivity of unknown molecules For the system of ALS enzyme inhibitor,this emthod can give reasonable predictions of the bioactivity of ALS enzyme inhibitor.展开更多
Close reading and inter-textual analysis of Borges＇ essays, fiction, and poetry suggest a poetics of visible unrealities, a fiction that calls attention to its own artifice. Borges＇s poetics of reading and dreaming ...Close reading and inter-textual analysis of Borges＇ essays, fiction, and poetry suggest a poetics of visible unrealities, a fiction that calls attention to its own artifice. Borges＇s poetics of reading and dreaming require another poetics of the work as a text that calls attention to its own artifice. In reading Borges＇ fiction, the separate roles and identities of reader, writer, and work of fiction merge and exchange roles, powers, and identities and are transformed into a single act of dreaming, which assumes cosmogonic and apocalyptic risks. In the dominant role given to the reader, the work of fiction as an object or work of art does not exist unless it is read. There is no determinate text, only a version of our own we re-write and invent every time we read the text. The author＇s reading is not a spontaneous evocation of vision, but an artifice, as artificial as the writing of the fiction. As writers and readers we are composed of texts and schemata, alphabets and artifacts, not merely mental perceptions and ideas. The reader requires a prior text to copy, translate, and recreate, and that text only exists as a fictional microcosm in so far as it is being read by a Reader who is able to actualize the revelation only imminent within it.展开更多
文摘We used genetic algorithm to construct pseudoreceptor site models and made use of the high correlation between interaction energy, which was between the models and the ligands,and bioactivity data of known molecules to predict the bioactivity of unknown molecules For the system of ALS enzyme inhibitor,this emthod can give reasonable predictions of the bioactivity of ALS enzyme inhibitor.
文摘Close reading and inter-textual analysis of Borges＇ essays, fiction, and poetry suggest a poetics of visible unrealities, a fiction that calls attention to its own artifice. Borges＇s poetics of reading and dreaming require another poetics of the work as a text that calls attention to its own artifice. In reading Borges＇ fiction, the separate roles and identities of reader, writer, and work of fiction merge and exchange roles, powers, and identities and are transformed into a single act of dreaming, which assumes cosmogonic and apocalyptic risks. In the dominant role given to the reader, the work of fiction as an object or work of art does not exist unless it is read. There is no determinate text, only a version of our own we re-write and invent every time we read the text. The author＇s reading is not a spontaneous evocation of vision, but an artifice, as artificial as the writing of the fiction. As writers and readers we are composed of texts and schemata, alphabets and artifacts, not merely mental perceptions and ideas. The reader requires a prior text to copy, translate, and recreate, and that text only exists as a fictional microcosm in so far as it is being read by a Reader who is able to actualize the revelation only imminent within it.
