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肺炎链球菌毒力因子研究新进展
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作者 刘丽 刘兆明 +1 位作者 朱德全 冯尚彩 《国际流行病学传染病学杂志》 CAS 2013年第4期270-273,共4页
肺炎链球菌(Spn)是临床重要的致病菌。Spn致病性与很多毒力因子有关。随着基因组学的研究和变异菌株的应用,人们除了更深入地了解Spn经典毒力因子外,也认识了其新的毒力因子。此文针对Spn毒力因子,包括荚膜多糖、菌毛、蛋白和蛋白... 肺炎链球菌(Spn)是临床重要的致病菌。Spn致病性与很多毒力因子有关。随着基因组学的研究和变异菌株的应用,人们除了更深入地了解Spn经典毒力因子外,也认识了其新的毒力因子。此文针对Spn毒力因子,包括荚膜多糖、菌毛、蛋白和蛋白酶等,对其生物活性和在菌株致病过程中的作用机制进行综述。 展开更多
关键词 链球菌 肺炎 毒力因子 荚膜多糖 菌毛 蛋白和蛋白酶
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Nanozymes: an emerging field bridging nanotechnology and biology 被引量:20
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作者 Lizeng Gao Xiyun Yan 《Science China(Life Sciences)》 SCIE CAS CSCD 2016年第4期400-402,共3页
Enzymes are biological catalysts that can convert substrates into products in biochemical reactions.In 1926,the first enzyme,urease,was determined to be a protein by James B.Sumner who won the Nobel Prize in 1946.Sinc... Enzymes are biological catalysts that can convert substrates into products in biochemical reactions.In 1926,the first enzyme,urease,was determined to be a protein by James B.Sumner who won the Nobel Prize in 1946.Since then,enzymes have been considered to be proteins,which allows them to achieve their high catalytic activity with high specific activity under mild conditions.However,in general,the enzyme activity of proteins is lost after exposure to extremes of p H and high temperature,and proteins are also susceptible to digestion by proteases in the environment,which dramatically hinders their practical applications in 展开更多
关键词 nanotechnology bridging digestion biochemical emerging exposure convert susceptible dramatically enzymes
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