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Protein sequence analysis based on hydropathy profile of amino acids
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作者 Xiao-li XIE Li-fei ZHENG +4 位作者 Ying YU Li-ping LIANG Man-cai GUO John SONG Zhi-fa YUAN 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2012年第2期152-158,共7页
Biology sequence comparison is a fundamental task in computational biology.According to the hydropathy profile of amino acids,a protein sequence is taken as a string with three letters.Three curves of the new protein ... Biology sequence comparison is a fundamental task in computational biology.According to the hydropathy profile of amino acids,a protein sequence is taken as a string with three letters.Three curves of the new protein sequence were defined to describe the protein sequence.A new method to analyze the similarity/dissimilarity of protein sequence was proposed based on the conditional probability of the protein sequence.Finally,the protein sequences of ND6(NADH dehydrogenase subunit 6)protein of eight species were taken as an example to illustrate the new approach.The results demonstrated that the method is convenient and efficient. 展开更多
关键词 Protein sequence Sequence comparison Similarity/dissimilarity Conditional probability
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