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两种融浆机融解冷沉淀及融解时间的长短对冷沉淀中凝血因子生物活性的影响 被引量:5
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作者 钟万芬 唐小勇 +1 位作者 孙凯 江华 《检验医学与临床》 CAS 2017年第18期2739-2741,共3页
目的探究干式融浆机和水溶式融浆机融解冷沉淀及融解时间长短对冷沉淀中凝血因子生物活性的影响。方法选取于2016年10月20至10月25日制备的冷沉淀血袋120袋,60袋冷沉淀血袋采用干式融浆机融解,另外60袋冷沉淀血袋采用水溶式融浆机融解,... 目的探究干式融浆机和水溶式融浆机融解冷沉淀及融解时间长短对冷沉淀中凝血因子生物活性的影响。方法选取于2016年10月20至10月25日制备的冷沉淀血袋120袋,60袋冷沉淀血袋采用干式融浆机融解,另外60袋冷沉淀血袋采用水溶式融浆机融解,观察并记录两种不同融浆方式以及不同融浆时间对冷沉淀凝血酶原时间(PT)、血浆凝血时间(TT)、活化部分凝血酶时间(APTT)、纤维蛋白原(Fib)、凝血因子(FⅧ)、血管性血友病因子(VWF)抗原活性等凝血功能指标的影响,并进行分析比较。结果在37℃条件下,水溶式融浆机融浆时间越长,融浆效果越好,报废例数越少。水溶式融浆机融浆时间越长,APTT时间也越长,血管性血友病因子(VWF)抗原和FⅧ活性也显著降低(P<0.05);但融浆时间对PT、TT及Fib无明显影响(P>0.05)。融浆时间长短对采用干式融浆机融解的冷沉淀PT、TT和Fib等凝血因子无明显影响(P>0.05);但APTT随融浆时间增加而显著延长,VWF抗原和FⅧ活性也明显降低(P<0.05)。结论不同融解方式对冷沉淀凝血因子活性影响不大,为保证多种凝血因子生物活性,将融解时间控制在10~15min较为理想,保证融浆效果也较好。 展开更多
关键词 干式融浆机 水溶式融浆机 冷沉淀 融解时间 凝血因子
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The Crucial Role of Time in M&A Activities: An Inductive Exploration
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作者 Nicole Zadrazil Othmar Lehner Heimo Losbichler 《Journal of Modern Accounting and Auditing》 2017年第8期350-370,共21页
Mergers & acquisitions (M&As) are important strategic instruments, yet nearly half of all transactions fail, often resulting in disastrous write-offs and losses for corporations and financing institutions alike - ... Mergers & acquisitions (M&As) are important strategic instruments, yet nearly half of all transactions fail, often resulting in disastrous write-offs and losses for corporations and financing institutions alike - despite promising prospects upfront. Applied research has been trying to find a "panacea" to prevent or at least predict M&A failure, investigating motives, synergies and performance. Despite the growing unease with the stationary explanatory models in literature, research has only marginally focused on the concept of time, with inquiries into market timing and integration speed. Yet other timing concepts have been neglected in concepts so far despite early empirical evidence for their existence. The purpose of this paper is thus to identify and elaborate on the importance of further relevant theories of timing. For this, and true to the exploratory nature of the topic, the authors have chosen a qualitative comparative case study design based on existing case reports which are investigated for narrations highlighting timing concepts. This study reveals six factors which have a crucial impact on the M&A outcome: time of acquisition, M&A duration in its entirety, M&A sequence, synergy chronology, frequency of acquisitions and time to step back. It contributes to theory and practice in outlining the careful attention that needs to be paid in planning in these factors to enhance the chances of a successful M&A transaction. 展开更多
关键词 M&A SUCCESS timing concepts process SYNERGY
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