[Objective] The aim of this study was to develop a simple and effective method for the polysaccharide extraction from Spirulina. [Method] The polysaccha- rides were directly extracted from the fresh algae mat or dry p...[Objective] The aim of this study was to develop a simple and effective method for the polysaccharide extraction from Spirulina. [Method] The polysaccha- rides were directly extracted from the fresh algae mat or dry powder of Spirulina in boiling water. The contents and quality of the extracted polysaccharides were measured. [Result] On average, 236.06 g of polysaccharide was extracted from 25 kg of fresh Spirulina mat, with a yield rate of 0.94%, while 191.95 g of polysac- charide was extracted from 2.5 kg of dry powder of Spirulina with a yield rate of 0.77%. The polysaccharide content in the extract of fresh Spirulina mat was 12.56% （according to glucose content）, while that of the dry powder was 12.38% （according to glucose content）; the glucose was produced during the hydrolysis of Spirulina polysaccharide. [Conclusion] Extraction polysaccharide from Spirulina with boiling wa- ter greatly reduces the use of ethanol, and the possibility of pollution from the ex- ogenous non-food chemical reagents, so that the extracted polysaccharides can be used as food materials. This method makes it possible to establish the production line for Spirulina polysaccharide.展开更多
The laser gyro is most su it able for building the strap down inertial navigation system (SINS), and its acc uracy of attitude algorithm can enormously affect that of the laser SINS. This p aper develops three improv...The laser gyro is most su it able for building the strap down inertial navigation system (SINS), and its acc uracy of attitude algorithm can enormously affect that of the laser SINS. This p aper develops three improved algorithmal expressions for strap down attitude ut ilizing the angular increment output by the laser gyro from the last two and cur rent updating periods according to the number of gyro samples, and analyses the algorithm error in the classical coning motion. Compared with the conventional algorithms, simulational results show that this improved algorithm has higher precision. A new way to improve the rotation vector algorithms is provided.展开更多
To avoid the machine problems of excessive axial force, complex process flow and frequent tool changing during robotic drilling holes, a new hole-making technology (i.e., helical milling hole) was introduced for desig...To avoid the machine problems of excessive axial force, complex process flow and frequent tool changing during robotic drilling holes, a new hole-making technology (i.e., helical milling hole) was introduced for designing a new robotic helical milling hole system, which could further improve robotic hole-making ability in airplane digital assembly. After analysis on the characteristics of helical milling hole, advantages and limitations of two typical robotic helical milling hole systems were summarized. Then, vector model of helical milling hole movement was built on vector analysis method. Finally, surface roughness calculation formula was deduced according to the movement principle of helical milling hole, then the influence of main technological parameters on surface roughness was analyzed. Analysis shows that theoretical surface roughness of hole becomes poor with the increase of tool speed ratio and revolution radius. Meanwhile, the roughness decreases according to the increase of tool teeth number. The research contributes greatly to the construction of roughness prediction model in helical milling hole.展开更多
Strain improvement and medium optimization to increase the productivity of spiramycin were carried out. Of oil tolerant mutant strains screened, one mutant, Streptomyces ambofaciens XC 2-37, produced 9% more spiramyc...Strain improvement and medium optimization to increase the productivity of spiramycin were carried out. Of oil tolerant mutant strains screened, one mutant, Streptomyces ambofaciens XC 2-37, produced 9% more spiramycin than the parent strain S. ambofaciens XC 1-29. The effects of soybean oil and propyl alcohol on spiramycin production with S. ambofaciens XC 2-37 were studied. The potency of S. ambofaciens XC 2-37 was improved by 61.8% with addition of 2% soybean oil in the fermentation medium and 0.4% propyl alcohol at 24 hours after incubation. The suitable time for feeding propyl alcohol is at 24 hours after incubation in flask fermentation and at 20 hours after incubation in fermentor fermentation. The new process with S. ambofaciens XC 2-37 was scaled up for industrial scale production of spiramycin in a 60 m3 fermentor in Xinchang Pharmaceutical Factory, Zhejiang Medicine Company, Ltd., China, and the potency and productivity of fermentation were improved by 42.9%.展开更多
Propeller blade width measurement has been extensively studied in the past using direct and indirect methods, and it plays a great role in determining the quality of the finished products. It has surveyed that previou...Propeller blade width measurement has been extensively studied in the past using direct and indirect methods, and it plays a great role in determining the quality of the finished products. It has surveyed that previous techniques are usually time-consuming and erroneous due to a large number of points to be processed in blade width measurement. This paper proposes a new method of measuring blade width using two images acquired from different viewpoints of the same blade. And a new feature points matching approach for propeller blade image is proposed in stereo vision measurement. Based on these, pixel coordinates of contour points of the blade in two images are extracted and converted to real world coordinates by image algorithm and binocular stereo machine vision theory. Then, from the real world coordinates, the blade width at any position can be determined by simple geometrical method.展开更多
In this paper, we review the concept of quality of ulcer healing （QOUH） in the gastrointestinal tract and its role in the ulcer recurrence. In the past, peptic ulcer disease （PUD） has been a chronic disease with a...In this paper, we review the concept of quality of ulcer healing （QOUH） in the gastrointestinal tract and its role in the ulcer recurrence. In the past, peptic ulcer disease （PUD） has been a chronic disease with a cycle of repeated healing/remission and recurrence. The main etiological factor of PUD is Helicobacter pylori （H. pylorl~, which is also the cause of ulcer recur- rence. However, H. pylori-negative ulcers are pres- ent in 12%-20% of patients; they also recur and are on occasion intractable. QOUH focuses on the fact that mucosal and submucosal structures within ulcer scars are incompletely regenerated. Within the scars of healed ulcers, regenerated tissue is immature and with distorted architecture, suggesting poor QOUH. The abnormalities in mucosal regeneration can be the basis for ulcer recurrence. Our studies have shown that persistence of macrophages in the regenerated area plays a key role in ulcer recurrence. Our studies in a rat model of ulcer recurrence have indicated that proinflammatory cytokines trigger activation of macro- phages, which in turn produce increased amounts of cytokines and chemokines, which attract neutrophils to the regenerated area. Neutrophils release proteolytic enzymes that destroy the tissue, resulting in ulcer re- currence. Another important factor in poor QOUH can be deficiency of endogenous prostaglandins and a defi- ciency and/or an imbalance of endogenous growth fac- tors. Topically active mucosal protective and antiulcer drugs promote high QOUH and reduce inflammatory cell infiltration in the ulcer scar. In addition to PUD, the concept of QOUH is likely applicable to inflammatory bowel diseases including Crohn＇s disease and ulcer- ative colitis.展开更多
Radiotherapy for locally advanced pancreatic cancer is technically difficult and frequently associated with high-grade digestive toxicity.Helical tomotherapy(HT)is a new irradiation modality that combines megavoltage ...Radiotherapy for locally advanced pancreatic cancer is technically difficult and frequently associated with high-grade digestive toxicity.Helical tomotherapy(HT)is a new irradiation modality that combines megavoltage computed tomography imaging for patient positioning with intensity-modulated fan-beam radiotherapy.Its recent availability opens new fields of exploration for pancreatic radiotherapy as a result of its ability to tailor very well-defined dose distributions around the target volumes.Here,we report the use of HT in two patients with locally advanced pancreatic cancer. Doses to the bowel,kidneys and liver were reduced significantly,which allowed for excellent treatment tolerance without any high-grade adverse effects in either patient.展开更多
In this study,the impact of environmental factors on tropical cyclone(TC)outer-core size was investigated for both migrating and local TCs in the South China Sea during the period 2001–2019.Among all the thermodynami...In this study,the impact of environmental factors on tropical cyclone(TC)outer-core size was investigated for both migrating and local TCs in the South China Sea during the period 2001–2019.Among all the thermodynamic and dynamic factors,the low-level environmental helicity showed the strongest positive correlation with TC outer-core size.Large helicity favors the development and organization of convection in TCs,and the corresponding strong inflow and large angular momentum fluxes into the system is beneficial for the maintenance and enlargement of TC outer-core size.Besides,the asymmetric distribution of helicity may account for the asymmetry of TC outer-core size.Therefore,the environmental helicity,as an integrated dynamic factor,can provide an alternative view on TC outer-core size.展开更多
Based on a barotropic vortex model, generalized energy-conserving equation was derived and twonecessary conditions of basic flow destabilization are gained. These conditions correspond to generalizedbarotropic instabi...Based on a barotropic vortex model, generalized energy-conserving equation was derived and twonecessary conditions of basic flow destabilization are gained. These conditions correspond to generalizedbarotropic instability and super speed instability. They are instabilities of vortex and gravity inertial waverespectively. In order to relate to practical situation, a barotropic vortex was analyzed, the basic flow of which issimilar to lower level basic wind field of tropical cyclones and the maximum wind radius of which is 500 km.The results show that generalized barotropic instability depending upon the radial gradient of relative vorticitycan appear in this vortex. It can be concluded that unstable vortex Rossby wave may appear in barotropic vortex.展开更多
1 INTRODUCTION Of three main methods for studying the radiative forcing of anthropogenic sulfate and climatic response on the regional scale, the first is, with given rates for transforming SO2 to sulfate, converting ...1 INTRODUCTION Of three main methods for studying the radiative forcing of anthropogenic sulfate and climatic response on the regional scale, the first is, with given rates for transforming SO2 to sulfate, converting actually released SO2 into sulfate and acquiring the distribution of sulfate by computing transfer equations in the climate model. The second is obtaining the sulfate distribution through chemical reaction and transfer of matters in regional climate models online coupled with an atmospheric chemistry model that includes full chemical reactions for sulfides. The third is to put sulfate distribution data from GCM and its coupled atmospheric chemistry model to regional climate model, which is so called off-line coupled method. As shown in comparisons between the online and offline modeling on the regional scale, the radiative climate effect of sulfate shows large uncertainty due to significant influence from various methods.展开更多
In order to provide instructions for the calculation of the propeller induced velocity in the study of the hull-propeller interaction using the body force approach,three methods were used to calculate the propeller in...In order to provide instructions for the calculation of the propeller induced velocity in the study of the hull-propeller interaction using the body force approach,three methods were used to calculate the propeller induced velocity：1） Reynolds-Averaged Navier-Stokes（RANS） simulation of the self-propulsion test,2） RANS simulation of the propeller open water test,and 3） momentum theory of the propeller.The results from the first two methods were validated against experimental data to assess the accuracy of the computed flow field.The thrust identity method was adopted to obtain the advance velocity,which was then used to derive the propeller induced velocity from the total velocity field.The results computed by the first two approaches were close,while those from the momentum theory were significantly overestimated.The presented results could prove to be useful for further calculations of self-propulsion using the body force approach.展开更多
文摘[Objective] The aim of this study was to develop a simple and effective method for the polysaccharide extraction from Spirulina. [Method] The polysaccha- rides were directly extracted from the fresh algae mat or dry powder of Spirulina in boiling water. The contents and quality of the extracted polysaccharides were measured. [Result] On average, 236.06 g of polysaccharide was extracted from 25 kg of fresh Spirulina mat, with a yield rate of 0.94%, while 191.95 g of polysac- charide was extracted from 2.5 kg of dry powder of Spirulina with a yield rate of 0.77%. The polysaccharide content in the extract of fresh Spirulina mat was 12.56% （according to glucose content）, while that of the dry powder was 12.38% （according to glucose content）; the glucose was produced during the hydrolysis of Spirulina polysaccharide. [Conclusion] Extraction polysaccharide from Spirulina with boiling wa- ter greatly reduces the use of ethanol, and the possibility of pollution from the ex- ogenous non-food chemical reagents, so that the extracted polysaccharides can be used as food materials. This method makes it possible to establish the production line for Spirulina polysaccharide.
文摘The laser gyro is most su it able for building the strap down inertial navigation system (SINS), and its acc uracy of attitude algorithm can enormously affect that of the laser SINS. This p aper develops three improved algorithmal expressions for strap down attitude ut ilizing the angular increment output by the laser gyro from the last two and cur rent updating periods according to the number of gyro samples, and analyses the algorithm error in the classical coning motion. Compared with the conventional algorithms, simulational results show that this improved algorithm has higher precision. A new way to improve the rotation vector algorithms is provided.
基金Foundation item： Projects（50975141, 51005118） supported by the National Natural Science Foundation of China Projects（20091652018, 2010352005） supported by Aviation Science Fund of China Project（YKJ11-001） supported by Key Program of Nanjing College of Information Technology Institute, China
文摘To avoid the machine problems of excessive axial force, complex process flow and frequent tool changing during robotic drilling holes, a new hole-making technology (i.e., helical milling hole) was introduced for designing a new robotic helical milling hole system, which could further improve robotic hole-making ability in airplane digital assembly. After analysis on the characteristics of helical milling hole, advantages and limitations of two typical robotic helical milling hole systems were summarized. Then, vector model of helical milling hole movement was built on vector analysis method. Finally, surface roughness calculation formula was deduced according to the movement principle of helical milling hole, then the influence of main technological parameters on surface roughness was analyzed. Analysis shows that theoretical surface roughness of hole becomes poor with the increase of tool speed ratio and revolution radius. Meanwhile, the roughness decreases according to the increase of tool teeth number. The research contributes greatly to the construction of roughness prediction model in helical milling hole.
文摘Strain improvement and medium optimization to increase the productivity of spiramycin were carried out. Of oil tolerant mutant strains screened, one mutant, Streptomyces ambofaciens XC 2-37, produced 9% more spiramycin than the parent strain S. ambofaciens XC 1-29. The effects of soybean oil and propyl alcohol on spiramycin production with S. ambofaciens XC 2-37 were studied. The potency of S. ambofaciens XC 2-37 was improved by 61.8% with addition of 2% soybean oil in the fermentation medium and 0.4% propyl alcohol at 24 hours after incubation. The suitable time for feeding propyl alcohol is at 24 hours after incubation in flask fermentation and at 20 hours after incubation in fermentor fermentation. The new process with S. ambofaciens XC 2-37 was scaled up for industrial scale production of spiramycin in a 60 m3 fermentor in Xinchang Pharmaceutical Factory, Zhejiang Medicine Company, Ltd., China, and the potency and productivity of fermentation were improved by 42.9%.
基金Supported by the Natural Science Foundation of China (50975133)the Innovative Foundation for Ph.D of the Jiangsu Province, China (2010-227)
文摘Propeller blade width measurement has been extensively studied in the past using direct and indirect methods, and it plays a great role in determining the quality of the finished products. It has surveyed that previous techniques are usually time-consuming and erroneous due to a large number of points to be processed in blade width measurement. This paper proposes a new method of measuring blade width using two images acquired from different viewpoints of the same blade. And a new feature points matching approach for propeller blade image is proposed in stereo vision measurement. Based on these, pixel coordinates of contour points of the blade in two images are extracted and converted to real world coordinates by image algorithm and binocular stereo machine vision theory. Then, from the real world coordinates, the blade width at any position can be determined by simple geometrical method.
文摘In this paper, we review the concept of quality of ulcer healing （QOUH） in the gastrointestinal tract and its role in the ulcer recurrence. In the past, peptic ulcer disease （PUD） has been a chronic disease with a cycle of repeated healing/remission and recurrence. The main etiological factor of PUD is Helicobacter pylori （H. pylorl~, which is also the cause of ulcer recur- rence. However, H. pylori-negative ulcers are pres- ent in 12%-20% of patients; they also recur and are on occasion intractable. QOUH focuses on the fact that mucosal and submucosal structures within ulcer scars are incompletely regenerated. Within the scars of healed ulcers, regenerated tissue is immature and with distorted architecture, suggesting poor QOUH. The abnormalities in mucosal regeneration can be the basis for ulcer recurrence. Our studies have shown that persistence of macrophages in the regenerated area plays a key role in ulcer recurrence. Our studies in a rat model of ulcer recurrence have indicated that proinflammatory cytokines trigger activation of macro- phages, which in turn produce increased amounts of cytokines and chemokines, which attract neutrophils to the regenerated area. Neutrophils release proteolytic enzymes that destroy the tissue, resulting in ulcer re- currence. Another important factor in poor QOUH can be deficiency of endogenous prostaglandins and a defi- ciency and/or an imbalance of endogenous growth fac- tors. Topically active mucosal protective and antiulcer drugs promote high QOUH and reduce inflammatory cell infiltration in the ulcer scar. In addition to PUD, the concept of QOUH is likely applicable to inflammatory bowel diseases including Crohn＇s disease and ulcer- ative colitis.
文摘Radiotherapy for locally advanced pancreatic cancer is technically difficult and frequently associated with high-grade digestive toxicity.Helical tomotherapy(HT)is a new irradiation modality that combines megavoltage computed tomography imaging for patient positioning with intensity-modulated fan-beam radiotherapy.Its recent availability opens new fields of exploration for pancreatic radiotherapy as a result of its ability to tailor very well-defined dose distributions around the target volumes.Here,we report the use of HT in two patients with locally advanced pancreatic cancer. Doses to the bowel,kidneys and liver were reduced significantly,which allowed for excellent treatment tolerance without any high-grade adverse effects in either patient.
基金This work was supported by the National Key Research and Development Program of China[grant number 2017YFC1501603]the National Natural Science Foundation of China[grant numbers 41675053,42175062,and 61827091].
文摘In this study,the impact of environmental factors on tropical cyclone(TC)outer-core size was investigated for both migrating and local TCs in the South China Sea during the period 2001–2019.Among all the thermodynamic and dynamic factors,the low-level environmental helicity showed the strongest positive correlation with TC outer-core size.Large helicity favors the development and organization of convection in TCs,and the corresponding strong inflow and large angular momentum fluxes into the system is beneficial for the maintenance and enlargement of TC outer-core size.Besides,the asymmetric distribution of helicity may account for the asymmetry of TC outer-core size.Therefore,the environmental helicity,as an integrated dynamic factor,can provide an alternative view on TC outer-core size.
基金Research on wave spectrum of Meso-beta-scale system and its application in severe weatherforecast, a project from National Natural Science Foundation of China (40575023)
文摘Based on a barotropic vortex model, generalized energy-conserving equation was derived and twonecessary conditions of basic flow destabilization are gained. These conditions correspond to generalizedbarotropic instability and super speed instability. They are instabilities of vortex and gravity inertial waverespectively. In order to relate to practical situation, a barotropic vortex was analyzed, the basic flow of which issimilar to lower level basic wind field of tropical cyclones and the maximum wind radius of which is 500 km.The results show that generalized barotropic instability depending upon the radial gradient of relative vorticitycan appear in this vortex. It can be concluded that unstable vortex Rossby wave may appear in barotropic vortex.
基金Natural Science Foundation of China (40205016)Natural Science Foundation of YunnanProvince (2005D0006M)Science Foundation for Post-Ph.D. in China (2004036295)
文摘1 INTRODUCTION Of three main methods for studying the radiative forcing of anthropogenic sulfate and climatic response on the regional scale, the first is, with given rates for transforming SO2 to sulfate, converting actually released SO2 into sulfate and acquiring the distribution of sulfate by computing transfer equations in the climate model. The second is obtaining the sulfate distribution through chemical reaction and transfer of matters in regional climate models online coupled with an atmospheric chemistry model that includes full chemical reactions for sulfides. The third is to put sulfate distribution data from GCM and its coupled atmospheric chemistry model to regional climate model, which is so called off-line coupled method. As shown in comparisons between the online and offline modeling on the regional scale, the radiative climate effect of sulfate shows large uncertainty due to significant influence from various methods.
基金Supported by European Union FP7 program,ICT-231646,SHOAL: Search and monitoring of Harmful contaminants, Other pollutants And Leaks in vessels in port using a swarm of robotic fish
文摘In order to provide instructions for the calculation of the propeller induced velocity in the study of the hull-propeller interaction using the body force approach,three methods were used to calculate the propeller induced velocity：1） Reynolds-Averaged Navier-Stokes（RANS） simulation of the self-propulsion test,2） RANS simulation of the propeller open water test,and 3） momentum theory of the propeller.The results from the first two methods were validated against experimental data to assess the accuracy of the computed flow field.The thrust identity method was adopted to obtain the advance velocity,which was then used to derive the propeller induced velocity from the total velocity field.The results computed by the first two approaches were close,while those from the momentum theory were significantly overestimated.The presented results could prove to be useful for further calculations of self-propulsion using the body force approach.
