Objective:To report 4 cases of biphenotypic acute leukemia(BAL)with t(8;21)(q22;q22),and analyze the characteristics of morphology,immune phenotype,chromosome karyotype(MIC)and clinical manifestations.Methods:The BAL ...Objective:To report 4 cases of biphenotypic acute leukemia(BAL)with t(8;21)(q22;q22),and analyze the characteristics of morphology,immune phenotype,chromosome karyotype(MIC)and clinical manifestations.Methods:The BAL patients with t(8;21)(q22;q22)(group A)were compared with the randomly selected BAL patients with other clonical chromo- somal changes(group B)and acute myeloid leukemia M2 cases with t(8;21)(q22;q22)(group C)in MIC and clinical features. Results:BAL with t(8;21)(q22;q22)showed acute myeloid leukemia with high percentages of blast cells morphologically; revealed co-positive to B-lymphoid and myeloid lineages,frequent and high expressions of CD34 and CD33;were responsive to chemotherapy for myeloid and lymphocytic leukemia simultaneously well.Conclusion:A new subset of BAL with t(8;21)(q22;q22)was reported,and this suggests that the leukemia colony with t(8;21)(q22;q22)might originate from early phase of hematopoiesis.展开更多
In this paper, we have discussed the biomathematical analysis of Sutterby fluid model for blood flow in stenosed tapered arteries. The equations for the Sutterby fluid model are modeled in cylindrical geometry. The eq...In this paper, we have discussed the biomathematical analysis of Sutterby fluid model for blood flow in stenosed tapered arteries. The equations for the Sutterby fluid model are modeled in cylindrical geometry. The equations have been developed for the ease of mild stenosis. Perturbation solutions are attained in terms of small Sutterby fluid parameter β for the velocity, impedance resistance and wall shear stress. Three types of arteries i.e. converging, diverging and non-tapered have been considered for the analysis and discussion. Graphical results have been presented for different parameters of interest. Streamlines have been plotted at the end of the paper.展开更多
基金in part by the Natural Science Fund of Jiangsu Province(2004BK424)the 135 Key Department Fund of Jiangsu Province(135XY0416)the Outstanding Person Fund of First Affiliated Hospital of Soochow University(2004YQG05).
文摘Objective:To report 4 cases of biphenotypic acute leukemia(BAL)with t(8;21)(q22;q22),and analyze the characteristics of morphology,immune phenotype,chromosome karyotype(MIC)and clinical manifestations.Methods:The BAL patients with t(8;21)(q22;q22)(group A)were compared with the randomly selected BAL patients with other clonical chromo- somal changes(group B)and acute myeloid leukemia M2 cases with t(8;21)(q22;q22)(group C)in MIC and clinical features. Results:BAL with t(8;21)(q22;q22)showed acute myeloid leukemia with high percentages of blast cells morphologically; revealed co-positive to B-lymphoid and myeloid lineages,frequent and high expressions of CD34 and CD33;were responsive to chemotherapy for myeloid and lymphocytic leukemia simultaneously well.Conclusion:A new subset of BAL with t(8;21)(q22;q22)was reported,and this suggests that the leukemia colony with t(8;21)(q22;q22)might originate from early phase of hematopoiesis.
文摘In this paper, we have discussed the biomathematical analysis of Sutterby fluid model for blood flow in stenosed tapered arteries. The equations for the Sutterby fluid model are modeled in cylindrical geometry. The equations have been developed for the ease of mild stenosis. Perturbation solutions are attained in terms of small Sutterby fluid parameter β for the velocity, impedance resistance and wall shear stress. Three types of arteries i.e. converging, diverging and non-tapered have been considered for the analysis and discussion. Graphical results have been presented for different parameters of interest. Streamlines have been plotted at the end of the paper.
