凝血酶激活的纤溶抑制物与深静脉血栓形成相关分析

目的:探讨凝血酶激活的纤溶抑制物(TAFI)与深静脉血栓(DVT)形成的关系。方法:应用发色底物法和ELISA法分别测定了30例DVT患者和30例正常对照者TAFI的活性及抗原。结果:DVT组TAFI的活性及抗原[TFAIAct(58.69±15.24)μg/ml,TAFI Ag(123.45±25.64)%]均较对照组[TAFI Act(30.15±9.36)μg/ml,TAFI Ag(69.35±24.13)%]显著增高(P<0.01)。结论:TAFI具有抑制纤溶的作用,可能与DVT形成有关。

布-加氏综合征治疗前后PAB、CHE、TBA变化的临床意义

目的:观察布-加氏综合征患者治疗前后血清前白蛋白(PAB)、总胆汁酸(TBA)及胆碱酯酶(CHE)的变化,探讨其临床意义。方法:用全自动生化分析仪测定80例患者(实验组)治疗前后血清PAB、TBA及CHE的水平,并与80例正常人(对照组)比较。结果:治疗前实验组各项指标与对照组比较差异有极显著性(P<0.01),治疗后PAB、CHE与对照组比较差异无显著性(P>0.05),TBA与对照组比较差异有显著性(P<0.05)。结论:PAB、CHE及TBA能敏感地反映肝脏合成、分泌及排泄功能,测定患者治疗前后几项指标的血清水平,有助于布-加氏综合征的病情观察、治疗及预后判断,尤其是TBA。

Dextrose in the banked blood products does not seem to affect the blood glucose levels in patients undergoing liver transplantation

AIM: Hyperglycemia commonly seen in liver transplantation (LT) has often been attributed to the dextrose in the storage solution of blood transfusion products. The purpose of the study is to compare the changes of the blood glucose levels in transfused and non-transfused patients during LT. METHODS: A retrospective study on 60 biliary pediatric patients and 16 adult patients undergoing LT was carried out. Transfused pediatric patients were included in Group Ⅰ (GⅠ), those not transfused in Group Ⅱ (GⅡ). Twelve adult patients were not given transfusion and assigned to Group Ⅲ(GⅢ); whereas, four adult patients who received massive transfusion were assigned to Group Ⅳ (GⅣ). The blood glucose levels, volume of blood transfused, and the volume of crystalloid infused were recorded, compared and analyzed. RESULTS: Results showed that the changes in blood glucose levels during LT for both non-transfused and minimally transfused pediatric groups and non-transfused and massively-transfused adult groups were almost the same. CONCLUSION: We conclude that blood transfusion does not cause significant changes in the blood glucose levels in this study.