Ischemic colitis is a rare complication of interferon administration.Only 9 cases in 6 reports have been described to-date.This report describes a case of ischemic colitis during pegylated interferon and ribavirin tre...Ischemic colitis is a rare complication of interferon administration.Only 9 cases in 6 reports have been described to-date.This report describes a case of ischemic colitis during pegylated interferon and ribavirin treatment for chronic hepatitis C,and includes a review of the relevant literature.A 48-year-old woman was treated with pegylated interferon-2a and ribavirin for chronic hepatitis C,genotype Ib.After 19 wk of treatment,the patient complained of severe afebrile abdominal pain with hematochezia.Vital signs were stable and serum white blood cell count was within the normal range.Abdominal computed tomography showed diffuse colonic wall thickening from the splenic flexure to the proximal sigmoid colon,which is the most vulnerable area for the development of ischemic colitis.Colonoscopy revealed an acute mucosal hyperemic change,with edema and ulcerations extending from the proximal descending colon to the sigmoid colon.Colonic mucosal biopsy revealed acute exudative colitis.Polymerase chain reaction and culture for Mycobacterium tuberculosis were negative and the cultures for cytomegalovirus,Salmonella and Shigella species were negative.After discontinuation of interferon and ribavirin therapy,abdominal pain and hematochezia subsided and,following colonoscopy showed improvement of the mucosal ulcerations.Ischemic colitis cases during interferon therapy in patients with chronic hepatitis C reported so far have all involved the descending colon.Ischemic colitis is a rarely encountered complication of interferon administration in patients with chronic hepatitis C and should be considered when a patient complains of abdominal pain and hematochezia.展开更多
Schistosomiasis, an important parasitic disease, is severely harmful to human heath in China . The beach along the Yangtze River is a important habitat of snail that is Schistosomiasis＇s only intermediate host. pro...Schistosomiasis, an important parasitic disease, is severely harmful to human heath in China . The beach along the Yangtze River is a important habitat of snail that is Schistosomiasis＇s only intermediate host. program of afforesting for wiping out snail（Oncomelania hupensisi） and Schistosomiasis, comprehensive administration and exploitation of the three kinds of beaches proposed by Peng Zhenhna and Jiang Zehui is a pioneering.work hased on the ecological and economic theory. The development process of forestry for snail control and Schistosomiasis prevention is reviewed, and mechanisms and major afforesting techniques are summarized in this paper.展开更多
文摘Ischemic colitis is a rare complication of interferon administration.Only 9 cases in 6 reports have been described to-date.This report describes a case of ischemic colitis during pegylated interferon and ribavirin treatment for chronic hepatitis C,and includes a review of the relevant literature.A 48-year-old woman was treated with pegylated interferon-2a and ribavirin for chronic hepatitis C,genotype Ib.After 19 wk of treatment,the patient complained of severe afebrile abdominal pain with hematochezia.Vital signs were stable and serum white blood cell count was within the normal range.Abdominal computed tomography showed diffuse colonic wall thickening from the splenic flexure to the proximal sigmoid colon,which is the most vulnerable area for the development of ischemic colitis.Colonoscopy revealed an acute mucosal hyperemic change,with edema and ulcerations extending from the proximal descending colon to the sigmoid colon.Colonic mucosal biopsy revealed acute exudative colitis.Polymerase chain reaction and culture for Mycobacterium tuberculosis were negative and the cultures for cytomegalovirus,Salmonella and Shigella species were negative.After discontinuation of interferon and ribavirin therapy,abdominal pain and hematochezia subsided and,following colonoscopy showed improvement of the mucosal ulcerations.Ischemic colitis cases during interferon therapy in patients with chronic hepatitis C reported so far have all involved the descending colon.Ischemic colitis is a rarely encountered complication of interferon administration in patients with chronic hepatitis C and should be considered when a patient complains of abdominal pain and hematochezia.
文摘Schistosomiasis, an important parasitic disease, is severely harmful to human heath in China . The beach along the Yangtze River is a important habitat of snail that is Schistosomiasis＇s only intermediate host. program of afforesting for wiping out snail（Oncomelania hupensisi） and Schistosomiasis, comprehensive administration and exploitation of the three kinds of beaches proposed by Peng Zhenhna and Jiang Zehui is a pioneering.work hased on the ecological and economic theory. The development process of forestry for snail control and Schistosomiasis prevention is reviewed, and mechanisms and major afforesting techniques are summarized in this paper.
