急进海拔5200m移居青年不同时间血液循环动力学动态观察

目的：为探讨急性暴露于高原低氧环境移居青年血液循环动力学变化规律及其在急性高原反应防治的关系；方法：随机对急进海拔5200m高原第3、30天20名部队健康青年进行了血循环动力学动态观察；结果：急进高原第3天，SV、SI、SVL、ETK、AC和BV显著降低，P、SDP、η显著升高，统计学处理（P＜0．05或P＜0·01）。第30天，上述指标较初入高原明显改善，但未恢复到平原水平，η和PAWP是进行性升高，BV始终未能恢复到平原水平（P＜0．01和P＜0．05）。结论；认为急进高原第3、30天青年血液循环动力学变化特点为低排高阻和有效血容量不足。最初以心功能减弱和血管顺应性降低伴全血粘度增加引起外周阻力加大为主，继而以全血粘度进行性升高，引起肺动脉契压增加，影响了心肺循环功能的结果，并讨论了与其防治的关系。

股腘动脉慢性完全闭塞病变分布及影响因素分析

目的探讨股腘动脉慢性完全闭塞（CTO）病变分布特征,分析不同致病危险因素对病变分布的影响。方法选择2013年1月至2015年5月首都医科大学附属北京世纪坛医院收治的经CTA、DSA检查证实的47例股腘动脉CTO患者,将股动脉均分为3段（F1-F3）,将腘动脉按骨性解剖标志分为3段（P1-P3）,基于股腘动脉CTA断层扫描、三维重建及DSA图像获取股腘动脉CTO病变解剖分布情况。采集影响病变分布的不同因素,并作多因素Logistic回归分析。结果共有47例患者59条股腘动脉CTO病变纳入研究。病变段平均长度为（12.91±10.13）cm。根据股腘动脉6段分法,病变累及F1段23肢,F2段34肢,F3段48肢,P1段18肢,P2段6肢,P3段5肢。多因素Logistic回归分析发现,高血压（RR=3.21）、吸烟史（RR=1.76）患者CTO病变最易累及F1段,男性（RR=1.98）患者CTO病变更易发生在P1段,而糖尿病患者病变分布RR值自血管近端至远端逐渐变大,说明病变更易累及远端血管。结论股腘动脉CTO病变分布具有特征性,与股腘动脉血流动力学及动脉硬化危险因素密切相关。

蛛网膜下腔出血患者白细胞介素-6变化特征

目的 了解蛛网膜下腔出血 (SAH )患者血清及脑脊液 (CSF)中白细胞介素 - 6 (IL - 6 )的动态变化特征 ,并研究 IL - 6与脑血液循环动力学、血糖等之间的关系。方法 选用双抗体夹心酶联免疫吸附试验 (EL ISA)检测 SAH组患者血清及 CSF中的 IL - 6浓度。将 IL - 6水平与临床各指标间关系进行了相关分析。结果 SA H组血清 IL- 6水平在急性期明显高于对照组 ,而 CSF中 IL- 6水平明显高于其血清中以及对照组 CSF中水平 ,且与血流动力学指标等具有相关性。结论 IL- 6在 SAH的发病机制及病理生理过程中起重要作用 ,早期检测血清中IL-

高血压病运动处方

高血压患者参加体育锻炼．有助于恢复大脑皮层兴奋与抑制过程的平衡．改善血液循环动力学条件．使血压下降．心脏负担减轻．并改善情绪．增强患者治疗疾病的信心和毅力．使其主动地与疾病做斗争。

Therapeutic efficacy of acupuncture plus Tuina for spastic cerebral palsy and discussion of its mechanism

Objective To discuss the effects of acupuncture plus Tuina(Chinese therapeutic massage)in intervening the mental development,motor function,cerebral hemodynamics,and muscle tone in kids with spastic cerebral palsy(CP).Methods A retrospective analysis was conducted on 87 kids with spastic CP.They were divided into a control group and an observation group based on their original treatment plan.Kids in the control group received symptomatic treatment,motor development therapy,and Tuina treatment.The observation group was additionally given acupuncture treatment.One month was taken as a treatment course.After six courses,the efficacy,change in muscle tone,mental development,gross motor function,fine motor function,and the systolic velocity(Vs),mean velocity(Vm),and pulsatility index(PI)of the anterior cerebral artery(ACA),middle cerebral artery(MCA),and posterior cerebral artery(PCA)were compared between the two groups.Results After treatment,the muscle tone score dropped in both groups(P<0.05)and was significantly lower in the observation group than in the control group(P<0.05).The observation group achieved more significant efficacy than the control group(P<0.05).After the intervention,the mental development index(MDI),psychomotor development index(PDI),gross motor function measure(GMFM)score,and fine motor function measure(FMFM)score all increased in both groups(P<0.05)and were notably higher in the observation group than in the control group(P<0.05).After treatment,the Vs and Vm of the ACA,MCA,and PCA were markedly higher in the observation group than in the control group(P<0.05),and the observation group was significantly lower than the control group comparing the PI of the ACA,MCA,and PCA(P<0.05).Conclusion Based on the symptomatic treatment and motor development therapy,Tuina and acupuncture treatment can effectively treat spastic CP children,manifesting as reducing muscle tone,boosting mental development,and improving motor function and cerebral hemodynamics.