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中西医结合治疗对血热症银屑病患者TNF-α、IL-18及IL-22的影响 被引量:2
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作者 顿耿 《亚太传统医药》 2017年第13期122-123,共2页
目的:探讨中西医结合治疗对血热症银屑病患者TNF-α、IL-18和IL-22的影响。方法:选取110例血热症银屑病患者作为研究对象,将所有患者随机分为观察组和对照组各55例,对照组患者采用常规药物治疗,观察组患者在对照组基础上加用中药治疗,... 目的:探讨中西医结合治疗对血热症银屑病患者TNF-α、IL-18和IL-22的影响。方法:选取110例血热症银屑病患者作为研究对象,将所有患者随机分为观察组和对照组各55例,对照组患者采用常规药物治疗,观察组患者在对照组基础上加用中药治疗,比较两组患者的临床疗效及TNF-α、IL-18和IL-22水平。结果:治疗前两组患者TNF-α、IL-18和IL-22水平比较差异无统计学意义(P>0.05);治疗后两组患者TNF-α、IL-18和IL-22水平比较,观察组均低于对照组,差异有统计学意义(P<0.05)。结论:中西医结合治疗血热症银屑病能降低患者血清中TNF-α、IL-18和IL-22水平,临床疗效明显优于单纯西医治疗,值得临床推广应用。 展开更多
关键词 血热症银屑病 肿瘤坏死因子-Α 白细胞介素-18 白细胞介素-22
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金诃降脂胶囊的血脂调节作用研究 被引量:1
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作者 周小梅 陈秋红 杨全余 《中成药》 CAS CSCD 北大核心 2003年第11期931-932,共2页
关键词 藏药 金诃降脂胶囊 高脂 肥胖症 血热症
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中药祛银汤对血热证银屑病患者疗效及外周血OPN、VEGF表达的影响 被引量:3
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作者 王磊 《中医临床研究》 2019年第35期104-106,共3页
目的:观察中药祛银汤对血热证银屑病患者的临床疗效以及外周血骨桥蛋白(Osteopontin,OPN)、血管内皮生长因子(Vascular Endothelial Growth Factor,VEGF)表达的影响。方法:选取我院在2017年1-12月就诊治疗的40例血热证银屑病患者,并将... 目的:观察中药祛银汤对血热证银屑病患者的临床疗效以及外周血骨桥蛋白(Osteopontin,OPN)、血管内皮生长因子(Vascular Endothelial Growth Factor,VEGF)表达的影响。方法:选取我院在2017年1-12月就诊治疗的40例血热证银屑病患者,并将其设定为实验组,对照组选取我院健康志愿者及健康医护人员共40例,其中实验组采用中药祛银汤进行治疗,观察实验组患者治疗前后的皮损面积和皮损严重程度,检测实验组患者治疗前后外周血中OPN、VEGF的表达情况,并与对照组正常人群进行比较。结果:患者服用中药祛银汤治疗56 d后,患者口渴、便秘、尿黄及心思不定症状有明显改善,患者治疗前外周血中OPN与VEGF的数据明显高于对照组健康志愿者,经治疗后,实验组患者外周血中的OPN与VEGF数据明显下降,但仍高于对照组外周血数据,患者PASI评分治疗前后为(16.27±4.38)分,(7.97±3.39)分。与治疗前对比,差异具有统计学意义(t=2.391,P<0.05)。结论:采用中药祛银汤治疗银屑病有明显临床效果,改善患者中医症状,降低外周血OPN与VEGF水平。 展开更多
关键词 中药祛银汤 血热症银屑病 外周骨桥蛋白 管内皮生长因子
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曲蛇消银汤治疗寻常型银屑病血热证患者的效果观察 被引量:2
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作者 朱晓涛 《中国民康医学》 2019年第20期128-129,共2页
目的:观察曲蛇消银汤治疗寻常型银屑病血热证患者的临床效果。方法:选取收治的120例寻常型银屑病血热证患者为研究对象,根据随机数字表法将其分为观察组和对照组,每组60例。观察组予曲蛇消银汤治疗,对照组予复方青黛胶囊治疗,比较两组... 目的:观察曲蛇消银汤治疗寻常型银屑病血热证患者的临床效果。方法:选取收治的120例寻常型银屑病血热证患者为研究对象,根据随机数字表法将其分为观察组和对照组,每组60例。观察组予曲蛇消银汤治疗,对照组予复方青黛胶囊治疗,比较两组患者治疗前后银屑病皮损面积和严重程度指数(PASI)评分、血管内皮生长因子(VEGF)水平,临床疗效及不良反应发生情况。结果:治疗后观察组治疗总有效率为95.00%,高于对照组的65.00%,差异有统计学意义(P<0.05)。两组治疗后PASI评分及血清VEGF水平均较治疗前降低,且观察组低于对照组,差异均有统计学意义(P<0.05)。结论:曲蛇消银汤治疗寻常型银屑病热证患者效果良好,不良反应少,值得临床推荐。 展开更多
关键词 曲蛇消银汤 寻常型银屑病 血热症
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红花清肝13味丸的临床应用 被引量:1
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作者 王海城 《中国民族医药杂志》 2008年第8期12-,共1页
关键词 红花清肝十三味丸 热症 热症 血热症
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Observation on the Efficiency of the Mongolian Gerbil Kidney Tissue Culture Inactivated Bivalent Vaccine for Hemorrhagic Fever with Renal Syndrome
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作者 董关木 朱智勇 +5 位作者 安祺 朱凤才 刘文雪 孔艳 杨立宏 俞永新 《Journal of Microbiology and Immunology》 2004年第2期115-119,共5页
The Z 10 and Z 37 strains of hemorrhagic fever with renal syndrome (HFRS) virus and the Mongolian gerbil ( Merions unguiculatus ) kidney cells were used to prepare the inactivated bivalent vaccine. A phase Ⅱ clinical... The Z 10 and Z 37 strains of hemorrhagic fever with renal syndrome (HFRS) virus and the Mongolian gerbil ( Merions unguiculatus ) kidney cells were used to prepare the inactivated bivalent vaccine. A phase Ⅱ clinical trial use of this vaccine was made in 750 Chinese volunteers. The results showed that the side reaction rate was 2.5% and the sero-conversion rate of neutralizing antibodies against Hantaan and Seoul viruses in the inoculated volunteers were 87.6% and 96.3% respectively. 展开更多
关键词 Bivalent HFRS vaccine Clinical reaction IFA antibody Neutralization antibody
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Hyperammonemia,brain edema and blood-brain barrier alterations in prehepatic portal hypertensive rats and paracetamol intoxication 被引量:5
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作者 Camila Scorticati Juan P.Prestifilippo +5 位作者 Francisco X.Eizayaga Salvador Romay MaríaA Fernández AbrahamLemberg Juan C.Perazzo José L.Castro 《World Journal of Gastroenterology》 SCIE CAS CSCD 2004年第9期1321-1324,共4页
AIM:To study the blood-brain barrier integrity,brain edema, animal behavior and ammonia plasma levels in prehepatic portal hypertensive rats with and without acute liver intoxication. METHODS:Adults male Wistar rats w... AIM:To study the blood-brain barrier integrity,brain edema, animal behavior and ammonia plasma levels in prehepatic portal hypertensive rats with and without acute liver intoxication. METHODS:Adults male Wistar rats were divided into four groups.Group Ⅰ:sham operation;Ⅱ:Prehepatic portal hypertension,produced by partial portal vein ligation;Ⅲ: Acetaminophen intoxication and Ⅳ:Prehepatic portal hypertension plus acetaminophen.Acetaminophen was administered to produce acute hepatic injury.Portal pressure,liver serum enzymes and ammonia plasma levels were determined.Brain cortex water content was registered and trypan blue was utilized to study blood brain barrier integrity.Reflexes and behavioral tests were recorded. RESULTS:Portal hypertension was significantly elevated in groups Ⅱ and Ⅳ.Uver enzymes and ammonia plasma levels were increased in groups Ⅱ,Ⅲ and Ⅳ.Prehepatic portal hypertension (group Ⅱ),acetaminophen intoxication (group Ⅲ) and both (group Ⅳ) had changes in the blood brain-barrier integrity (trypan blue) and hyperammonemia.Cortical edema was present in rats with acute hepatic injury in groups Ⅲ and Ⅳ.Behavioral test (rota rod) was altered in group Ⅳ. CONCLUSION:These results suggest the possibility of another pathway for cortical edema production because blood brain barrier was altered (vasogenic) and hyperammonemia was registered (oltotoxic).Group Ⅳ,with behavioral altered test,can be considered as a model for study at an early stage of portal-systemic encephalopathy. 展开更多
关键词 Acetaminophen Analgesics Non-Narcotic Animals Behavior Animal Blood-Brain Barrier Brain Edema Humans HYPERAMMONEMIA Hypertension Portal Liver Male RATS Rats Wistar
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ACUPUNCTURE TREATMENT OF 42 CASES OF ACUTE UPPER RESPIRATORY TRACT INFECTION
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作者 满伟 王敬兰 《World Journal of Acupuncture-Moxibustion》 2000年第3期21-23,共3页
We made clinical observations on the therapeutic effect of acupuncture on acute upper respiratory tract infection and compared with the effect of paracetamol and Antondine, The result showed that acupuncture therapy c... We made clinical observations on the therapeutic effect of acupuncture on acute upper respiratory tract infection and compared with the effect of paracetamol and Antondine, The result showed that acupuncture therapy could allay fever more rapidly than drugs, so long as the differentiation of syndromes is correct and the acupoint is selected properly. 展开更多
关键词 Acute upper respiratory tract infection Fever Acupuncture therapy Blood letting
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