血红细胞形态结合红细胞参数在初诊恶性贫血与巨幼红细胞性贫血中的应用

研究血红细胞形态结合红细胞参数在初诊恶性贫血与巨幼红细胞性贫血中的应用效果。方法:在本文研究中将初诊恶性贫血与巨幼红细胞性贫血患者作为研究对象,100例收治时间在2019年度12月-2020年度12月,将其作为观察组,另同期选择100名健康体检者作为对照组,对两组受检者均实施血红细胞形态结合红细胞参数诊断,从而明确诊断效果,分析血红细胞形态、LFR、LFR、RET、RET、MFR、IRF指标。结果:观察组MCV(99.86±2.11)fl,高于对照组,MCH(33.52±1.64)pg,高于对照组,RBC低于对照组(P<0.05);两组HCT、MCHC、RDW-CV、RDW-SD相比无明显差异(P>0.05);观察组LFR高于对照组,观察组LFR(88.82±1.41)%、RET(1.80±0.21)%、RET#(0.05±0.01)×1012/L、MFR(6.20±1.02)%、IRF(7.12±1.15)%、HFR(0.71±0.06)%低于对照组(P<0.05)。结论:血红细胞形态结合红细胞参数在初诊恶性贫血与巨幼红细胞性贫血中具有较好的应用效果,并且能够利于疾病的后期治疗,改善患者病情的预后情况。

血尿的实验室检验及临床应用分析

目的探讨血尿实验室检验的方法及临床意义。方法 1 596份标本利用干化学尿液分析仪检验,UF-100流式尿沉渣分析仪和光学显微镜进行离心沉渣镜检。结果仪器与镜检符合率为80.7%(1 288/1 596),仪器与干化学仪符合率为71.2%(1 136/1 596),显微镜与干化学仪符合率为75.5%(1 205/1 596),差异有统计学意义(P<0.05)。结论 UF-100流式尿沉渣分析仪检测尿红细胞较敏感准确、客观可靠,是一种有价值的鉴别肾性和非肾性血尿的过筛试验;干化学仪快捷,但假阳性和假阴性率高;显微镜检查法是尿液有形成分检查的金标准。3种方法有机结合、交叉互补是血尿检验理想的选择。

AGING OF HUMAN MATURE ERYTHROCYTES IS LIKE A PROCESS OF APOPTOSIS IN ENUCLEATED CELL

Apoptosis of nucleated cells is well known, but how about the unnucleated cells is still not elucidated. In the present paper, the morphological and biochemical features of the aged erythrocytes were observed and compared with the characteristic events of apoptosis. Membrane of aged erythrocytes tends to shrink, protrude, from vesicle and lose lipid asymmetry. Aged erythrocytes were removed by phagocytosis. Both of the events are very similar to the apoptotic nucleated cells. The authors suggested that aging of erythro- cytes is also a process of apoptosis.