目的探讨联合检测D二聚体(D-D)与活化部分凝血活酶时间(aPTT)、凝血酶调节蛋白(TM)对乳腺癌术后下肢深静脉血栓形成(DVT)的临床价值。方法选取2017年12月-2018年12月我院收治的乳腺癌术后并发DVT患者60例,对照组患者选择同期我院收治的...目的探讨联合检测D二聚体(D-D)与活化部分凝血活酶时间(aPTT)、凝血酶调节蛋白(TM)对乳腺癌术后下肢深静脉血栓形成(DVT)的临床价值。方法选取2017年12月-2018年12月我院收治的乳腺癌术后并发DVT患者60例,对照组患者选择同期我院收治的乳腺癌术后未发生DVT患者80例,对比两组患者手术前后D-D、aPTT和TM水平变化及分析其与乳腺癌术后并发DVT的相关性。结果两组患者术前D-D、aPTT、TM水平差异无统计学意义(P>0.05);实验组患者术后24 h和48 h D-D和TM水平显著高于对照组,aPTT水平显著低于对照组(P<0.05);联合检测D-D、TM和aPTT组的特异性、阳性率和敏感性显著高于单一检测;经Pearson相关系数分析,实验组患者血清D-D、TM和aPTT水平与乳腺癌术后并发DVT的发生呈正相关。结论联合检测对D-D,TM和aPTT水平对乳腺癌术后下肢DVT的早期诊断具有重要临床价值。展开更多
We describe the case of a 79-year-old male presented with sudden onset of abdominal pain and mild breathlessness, and complicated acute progressive anemia with haemoglobin which declined from 120 g/L to 70 g/L within ...We describe the case of a 79-year-old male presented with sudden onset of abdominal pain and mild breathlessness, and complicated acute progressive anemia with haemoglobin which declined from 120 g/L to 70 g/L within five days. An urgent computed tomography an- giography showed acute thoracic aortic dissection, DeBakey type IIIb, a dissecting aneurysm in the proximal descending thoracic aorta start- ing immediately after the origin of the left subclavian artery and extending distally below the renal arteries with evidence of rupture into the right pleural cavity for massive pleural effusion. Plasma D-dimer, brain natriuretic peptide and C reactive protein level were elevated. Our case showed that D-dimer can be used as a ＇rule-out＇ test in patients with suspected aortic dissection. A raised BNP may exert a protective role through anti-inflammatory endothelial actions in the systemic circulation.展开更多
OBJECTIVE:To compare the effects of electrical stimulation of different acupoint combinations among postoperative bedridden elderly patients on hemorheology and deep venous blood flow velocity and investigate the role...OBJECTIVE:To compare the effects of electrical stimulation of different acupoint combinations among postoperative bedridden elderly patients on hemorheology and deep venous blood flow velocity and investigate the role of electrical stimulation against deep vein thrombosis(DVT).METHODS:From November 2010 to October 2011,a total of 160 elderly bedridden patients after major surgery were divided into the conventional care group,invigorating and promoting Qi group,blood-activating and damp-eliminating group,and acupoint-combination stimulation group.Whole blood viscosity,plasma viscosity,D-dimer levels,lower limb skin temperature,lower limb circumference,and flow velocities of the external iliac vein,femoral vein,popliteal vein,and deep calf veins in all patients were documented and compared among the four groups.RESULTS:Whole blood viscosity,plasma viscosity,D-dimer levels,and lower limb circumference were significantly reduced in the blood-activating and damp-eliminating group compared with the conventional care group(P<0.05) and were almost equal to those in the acupoint-combination stimulation group(P>0.05).Lower limb venous flow velocities were accelerated in the invigorating and promoting Qi group compared with the other groups,excluding the acupoint-combination stimulation group(P<0.05).CONCLUSION:Hemorheological indices in postoperative bedridden elderly patients were improved after combined electrical stimulation at Yinlingquan(SP 9) and Sanyinjiao(SP 6).Combined electrical stimulation at Zusanli(ST 36) and Taichong(LR 3),on the other hand,accelerated lower limb venous flow.展开更多
文摘目的探讨联合检测D二聚体(D-D)与活化部分凝血活酶时间(aPTT)、凝血酶调节蛋白(TM)对乳腺癌术后下肢深静脉血栓形成(DVT)的临床价值。方法选取2017年12月-2018年12月我院收治的乳腺癌术后并发DVT患者60例,对照组患者选择同期我院收治的乳腺癌术后未发生DVT患者80例,对比两组患者手术前后D-D、aPTT和TM水平变化及分析其与乳腺癌术后并发DVT的相关性。结果两组患者术前D-D、aPTT、TM水平差异无统计学意义(P>0.05);实验组患者术后24 h和48 h D-D和TM水平显著高于对照组,aPTT水平显著低于对照组(P<0.05);联合检测D-D、TM和aPTT组的特异性、阳性率和敏感性显著高于单一检测;经Pearson相关系数分析,实验组患者血清D-D、TM和aPTT水平与乳腺癌术后并发DVT的发生呈正相关。结论联合检测对D-D,TM和aPTT水平对乳腺癌术后下肢DVT的早期诊断具有重要临床价值。
文摘We describe the case of a 79-year-old male presented with sudden onset of abdominal pain and mild breathlessness, and complicated acute progressive anemia with haemoglobin which declined from 120 g/L to 70 g/L within five days. An urgent computed tomography an- giography showed acute thoracic aortic dissection, DeBakey type IIIb, a dissecting aneurysm in the proximal descending thoracic aorta start- ing immediately after the origin of the left subclavian artery and extending distally below the renal arteries with evidence of rupture into the right pleural cavity for massive pleural effusion. Plasma D-dimer, brain natriuretic peptide and C reactive protein level were elevated. Our case showed that D-dimer can be used as a ＇rule-out＇ test in patients with suspected aortic dissection. A raised BNP may exert a protective role through anti-inflammatory endothelial actions in the systemic circulation.
基金Supported by the Construct Program of the Key Discipline of State Administration of Traditional Chinese Medicine of the People's Republic of China and by the Science and Technology Development Fund of the Shanghai Municipal Public Health Bureau (No. 2011Y200,2008Y127,and 2005L019A)
文摘OBJECTIVE:To compare the effects of electrical stimulation of different acupoint combinations among postoperative bedridden elderly patients on hemorheology and deep venous blood flow velocity and investigate the role of electrical stimulation against deep vein thrombosis(DVT).METHODS:From November 2010 to October 2011,a total of 160 elderly bedridden patients after major surgery were divided into the conventional care group,invigorating and promoting Qi group,blood-activating and damp-eliminating group,and acupoint-combination stimulation group.Whole blood viscosity,plasma viscosity,D-dimer levels,lower limb skin temperature,lower limb circumference,and flow velocities of the external iliac vein,femoral vein,popliteal vein,and deep calf veins in all patients were documented and compared among the four groups.RESULTS:Whole blood viscosity,plasma viscosity,D-dimer levels,and lower limb circumference were significantly reduced in the blood-activating and damp-eliminating group compared with the conventional care group(P<0.05) and were almost equal to those in the acupoint-combination stimulation group(P>0.05).Lower limb venous flow velocities were accelerated in the invigorating and promoting Qi group compared with the other groups,excluding the acupoint-combination stimulation group(P<0.05).CONCLUSION:Hemorheological indices in postoperative bedridden elderly patients were improved after combined electrical stimulation at Yinlingquan(SP 9) and Sanyinjiao(SP 6).Combined electrical stimulation at Zusanli(ST 36) and Taichong(LR 3),on the other hand,accelerated lower limb venous flow.
