Caveolin-2,a protein about 20 kD,is a major component of the inner surface of caveolae,small invaginations of the plasma membrane.Similar with caveolin-1 and caveolin-3,it serves as a protein marker of caveolae.Caveol...Caveolin-2,a protein about 20 kD,is a major component of the inner surface of caveolae,small invaginations of the plasma membrane.Similar with caveolin-1 and caveolin-3,it serves as a protein marker of caveolae.Caveolin-1 and-2 are located next to each other at 7q31.1 on human chromosome,the proteins encoded are co-localized and form a stable hetero-oligomeric complex,distributing similarly in tissue and cultured cells.Caveolin-3 is located on different chromosomes but confirmed to interact with caveolin-2.Caveolin-2 is similar to caveolin-1 in many respects but differs from the latter in functional domains,especially in G-protein binding domain and caveolin scaffolding domain.The mRNAs of both caveolin-1 and caveolin-2 are most abundantly expressed in white adipose tissue and are induced during differentiation of 3T3-L1 cells to adipocytes.Caveolin-2-deficinet mice demonstrate clear pulmonary defects,with little or no change in caveolin-1 expression and caveolae formation,suggesting that caveolin-2 plays a selective role in lung functions.Caveolin-2 is also involved in lipid metabolism and human cancers.展开更多
The Gaussian vortex beam is assumed to be linearly polarized.The analytical expression of the electric field of a linearly polarized Gaussian vortex beam propagating in free space is derived by using the vectorial Ray...The Gaussian vortex beam is assumed to be linearly polarized.The analytical expression of the electric field of a linearly polarized Gaussian vortex beam propagating in free space is derived by using the vectorial Rayleigh-Sommerfeld integral formulae.The propagating magnetic field of the linearly polarized Gaussian vortex beam is presented by taking the curl of the electric field.By employing the electromagnetic field of the linearly polarized Gaussian vortex beam beyond the paraxial approximation,the analytical expression of the angular momentum density of the linearly polarized Gaussian vortex beam is derived.The three components of the angular momentum density of a linearly polarized Gaussian vortex beam are demonstrated in the reference plane.The effects of the linearly polarized angle and the topological charge on the three components of the angular momentum density are investigated.To acquire the more longitudinal angular momentum density requires such an optimal choice that the linearly polarized angle is set to be zero and the topological charge increases.This research is useful to the optical trapping,the optical guiding,and the optical manipulation.展开更多
基金Supported by National Basic Research Program of China (973 Program) (2004CB518602,2006CB503909)National High Technology Research and Development Program of China (863 Program) (2009AA02Z192)
文摘Caveolin-2,a protein about 20 kD,is a major component of the inner surface of caveolae,small invaginations of the plasma membrane.Similar with caveolin-1 and caveolin-3,it serves as a protein marker of caveolae.Caveolin-1 and-2 are located next to each other at 7q31.1 on human chromosome,the proteins encoded are co-localized and form a stable hetero-oligomeric complex,distributing similarly in tissue and cultured cells.Caveolin-3 is located on different chromosomes but confirmed to interact with caveolin-2.Caveolin-2 is similar to caveolin-1 in many respects but differs from the latter in functional domains,especially in G-protein binding domain and caveolin scaffolding domain.The mRNAs of both caveolin-1 and caveolin-2 are most abundantly expressed in white adipose tissue and are induced during differentiation of 3T3-L1 cells to adipocytes.Caveolin-2-deficinet mice demonstrate clear pulmonary defects,with little or no change in caveolin-1 expression and caveolae formation,suggesting that caveolin-2 plays a selective role in lung functions.Caveolin-2 is also involved in lipid metabolism and human cancers.
基金supported by the National Natural Science Foundation of China(Grant Nos.61178016 and 10974179)Zhejiang Provincial Natural Science Foundation of China(Grant No.Y1090073)
文摘The Gaussian vortex beam is assumed to be linearly polarized.The analytical expression of the electric field of a linearly polarized Gaussian vortex beam propagating in free space is derived by using the vectorial Rayleigh-Sommerfeld integral formulae.The propagating magnetic field of the linearly polarized Gaussian vortex beam is presented by taking the curl of the electric field.By employing the electromagnetic field of the linearly polarized Gaussian vortex beam beyond the paraxial approximation,the analytical expression of the angular momentum density of the linearly polarized Gaussian vortex beam is derived.The three components of the angular momentum density of a linearly polarized Gaussian vortex beam are demonstrated in the reference plane.The effects of the linearly polarized angle and the topological charge on the three components of the angular momentum density are investigated.To acquire the more longitudinal angular momentum density requires such an optimal choice that the linearly polarized angle is set to be zero and the topological charge increases.This research is useful to the optical trapping,the optical guiding,and the optical manipulation.
