Gas–liquid flow in serpentine microchannel with different surface properties exhibits drastically different flow behavior. With water and air as working fluids, the method of numerical simulation was adopted in this ...Gas–liquid flow in serpentine microchannel with different surface properties exhibits drastically different flow behavior. With water and air as working fluids, the method of numerical simulation was adopted in this paper based on CLSVOF(coupled level set and volume of fluid method) multiphase model. After verifying the reasonability of the model through experiment, by changing wall properties and Re number(Re<1500), the influences of contact angle and surface roughness on flow regime and Po number were discussed. Moreover, the difference of pressure drop between curve and straight microchannel was also calculated. Beyond that, the combined effect of curve channel and wall properties on flow resistance was analyzed. This paper finds that wall properties have great influence on gas–liquid flow in microchannels not only on flow regime but also flow characteristics. Meanwhile, the pressure drop in curve microchannels is larger than straight. It is more beneficial for fluid flowing when the straight part of microchannel is hydrophilic smooth wall and curve part is hydrophobic with large roughness.展开更多
Tribological characteristics and self-repairing effect of hydroxy-magnesium silicate (HMS) dispersed in lubricant oil on steel-to-steel friction pairs with various surface roughness were analyzed.The friction-reductio...Tribological characteristics and self-repairing effect of hydroxy-magnesium silicate (HMS) dispersed in lubricant oil on steel-to-steel friction pairs with various surface roughness were analyzed.The friction-reduction,anti-wear and self-repairing performance of various surface roughness friction pairs were examined by friction testing machine.An operation comparison was made between SJ10W-40 lubricant with and without HMS.The surface morphology and elementary composition of the grinding cracks were analyzed by scanning electron microscope (SEM) and energy dispersive spectrometer (EDS).The results show that the lubrication state changes from boundary lubrication into mixed lubrication after operation in lubricant with HMS.The friction-reduction,anti-wear and self-repairing performance of the friction pairs with various surface roughness are distinctly different.There is a repairing film whose material is different from substrate material on the grinding cracks.In addition,Si,Mg,O,Al and other elements are deposited on the repairing film which contains nanocrystals of these elements.And HMS self-repairing material possesses superior performance of friction-reduction,anti-wear and self-repairing effects.展开更多
The fabrication of superhydrophobic surfaces and the studies on water flow characteristics therein are of great significance to many industrial areas as well as to science and technology development. Experiments were ...The fabrication of superhydrophobic surfaces and the studies on water flow characteristics therein are of great significance to many industrial areas as well as to science and technology development. Experiments were car- ried out to investigate slip characteristics of water flowing in circular superhydrophobic microtubes within lam- inar flow region. The superhydrophobic microtubes of stainless steel were fabricated with chemical etching- fluorination treatment. An experimental setup was designed to measure the pressure drop as function of water flow rate. For comparison, superhydrophilic tubes were also tested. Poiseuille number Po was found to be smaller for the superhydrophobic microtubes than that for superhydrophilic ones. The pressure drop reduc- tion ranges from 8% to 31%. It decreases with increasing Reynolds number when Re 〈 900, owing to the transition from Cassie state to Wenze] state. However, it is almost unchanged with further increasing Re after Re 〉 900. The slip length in superhydrophobic microtubes also exhibits a Reynolds number dependence similarly to the pressure drop reduction. The relation between slip length and Darcy friction factor is theoretically analyzed with consideration of surface roughness effect, which was testified with the experimental results.展开更多
The role of roughness and composition on the wetting characteristics of a series of carbon nanofiber based coatings were studied in order to evaluate its superhydrophobic properties. In this study, idealized surfaces ...The role of roughness and composition on the wetting characteristics of a series of carbon nanofiber based coatings were studied in order to evaluate its superhydrophobic properties. In this study, idealized surfaces were created from a smooth stainless steel and aluminium sheets and two other stainless steel sheets with different textured surfaces. All surfaces were coated with carbon nanofiber alcohol solutions in order to generate coatings of variable compositions using mixtures of isopropanol, water and a commercial carbon nanofibre. The optimum concentration of carbon nanofiber in coatings was obtained to produce superhydrophobic surfaces. A general trend of increasing hydrophobicity was observed for coated surfaces as compared to the bare substrate. Individual contact angles were dependent on the nature of the underlying substrate, relative surface pattern, and roughness. Overall wetting properties were dependent upon composition and micro scale roughness of the coatings.展开更多
The existing surface roughness standards comprise only two dimensions. However, the real roughness of the surface is 3D (three-dimensional). Roughness parameters of the 3D surface are also important in analyzing the...The existing surface roughness standards comprise only two dimensions. However, the real roughness of the surface is 3D (three-dimensional). Roughness parameters of the 3D surface are also important in analyzing the mechanics of contact surfaces. Problems of mechanics of contact surfaces are related to accuracy of 3D surface roughness characteristic. One of the most important factors for 3D characteristics determination is the number of data points per x and y axes. With number of data points we understand its number in cut-off length. Number of data points have substantial influence on the accuracy of measurement results, measuring time and size of output data file (especially along the y-axis direction, where number of data points are number of parallel profiles). Number of data points must be optimal. Small number of data points lead to incorrect results and increase distribution amplitude, but too large number of data points do not enlarge range of fundamental information, but substantially increase measuring time. Therefore, we must find optimal number of data points per each surface processing method.展开更多
The human ether-a-go-go related gene (hERG) channel is responsible for the repolarization during the action potential, and blockage of that may result in severe cardiotoxicity and sudden death. In this study, a data...The human ether-a-go-go related gene (hERG) channel is responsible for the repolarization during the action potential, and blockage of that may result in severe cardiotoxicity and sudden death. In this study, a dataset containing 1969 compounds was compiled from literature and FDA-approved drugs. Using a support vector machine (SVM), two groups of computational models were built to distinguish whether a compound is a blocker or non-blocker of hERG potassium ion channel. These mod- els fit generally satisfactory. The 100 models built with MACCS fingerprints (Model Group A) showed an average accuracy of 90% and an average matthews correlation coefficient (MCC) value of 0.77 on the test sets. The 100 models built with selected MOE descriptors (Model Group B) showed an average accuracy of 89% and an average MCC value of 0.74 on the test sets. Molecular hydrophobicity and lipophilicity were found to be very important factors which lead to block the hERG potassium ion channel. Some other molecular properties such as electrostatic properties, features based on van der Waals surface area, the number of rigid bonds and molecular surface rugosity also played important roles in blocking bERG potassium ion channel.展开更多
文摘Gas–liquid flow in serpentine microchannel with different surface properties exhibits drastically different flow behavior. With water and air as working fluids, the method of numerical simulation was adopted in this paper based on CLSVOF(coupled level set and volume of fluid method) multiphase model. After verifying the reasonability of the model through experiment, by changing wall properties and Re number(Re<1500), the influences of contact angle and surface roughness on flow regime and Po number were discussed. Moreover, the difference of pressure drop between curve and straight microchannel was also calculated. Beyond that, the combined effect of curve channel and wall properties on flow resistance was analyzed. This paper finds that wall properties have great influence on gas–liquid flow in microchannels not only on flow regime but also flow characteristics. Meanwhile, the pressure drop in curve microchannels is larger than straight. It is more beneficial for fluid flowing when the straight part of microchannel is hydrophilic smooth wall and curve part is hydrophobic with large roughness.
基金Projects(50735006,50904072) supported by the National Natural Science Foundation of ChinaProject(2007CB607601) supported by the National Basic Research Program of China
文摘Tribological characteristics and self-repairing effect of hydroxy-magnesium silicate (HMS) dispersed in lubricant oil on steel-to-steel friction pairs with various surface roughness were analyzed.The friction-reduction,anti-wear and self-repairing performance of various surface roughness friction pairs were examined by friction testing machine.An operation comparison was made between SJ10W-40 lubricant with and without HMS.The surface morphology and elementary composition of the grinding cracks were analyzed by scanning electron microscope (SEM) and energy dispersive spectrometer (EDS).The results show that the lubrication state changes from boundary lubrication into mixed lubrication after operation in lubricant with HMS.The friction-reduction,anti-wear and self-repairing performance of the friction pairs with various surface roughness are distinctly different.There is a repairing film whose material is different from substrate material on the grinding cracks.In addition,Si,Mg,O,Al and other elements are deposited on the repairing film which contains nanocrystals of these elements.And HMS self-repairing material possesses superior performance of friction-reduction,anti-wear and self-repairing effects.
基金the National Natural Science Foundation of China(20476014,51376030)
文摘The fabrication of superhydrophobic surfaces and the studies on water flow characteristics therein are of great significance to many industrial areas as well as to science and technology development. Experiments were car- ried out to investigate slip characteristics of water flowing in circular superhydrophobic microtubes within lam- inar flow region. The superhydrophobic microtubes of stainless steel were fabricated with chemical etching- fluorination treatment. An experimental setup was designed to measure the pressure drop as function of water flow rate. For comparison, superhydrophilic tubes were also tested. Poiseuille number Po was found to be smaller for the superhydrophobic microtubes than that for superhydrophilic ones. The pressure drop reduc- tion ranges from 8% to 31%. It decreases with increasing Reynolds number when Re 〈 900, owing to the transition from Cassie state to Wenze] state. However, it is almost unchanged with further increasing Re after Re 〉 900. The slip length in superhydrophobic microtubes also exhibits a Reynolds number dependence similarly to the pressure drop reduction. The relation between slip length and Darcy friction factor is theoretically analyzed with consideration of surface roughness effect, which was testified with the experimental results.
文摘The role of roughness and composition on the wetting characteristics of a series of carbon nanofiber based coatings were studied in order to evaluate its superhydrophobic properties. In this study, idealized surfaces were created from a smooth stainless steel and aluminium sheets and two other stainless steel sheets with different textured surfaces. All surfaces were coated with carbon nanofiber alcohol solutions in order to generate coatings of variable compositions using mixtures of isopropanol, water and a commercial carbon nanofibre. The optimum concentration of carbon nanofiber in coatings was obtained to produce superhydrophobic surfaces. A general trend of increasing hydrophobicity was observed for coated surfaces as compared to the bare substrate. Individual contact angles were dependent on the nature of the underlying substrate, relative surface pattern, and roughness. Overall wetting properties were dependent upon composition and micro scale roughness of the coatings.
文摘The existing surface roughness standards comprise only two dimensions. However, the real roughness of the surface is 3D (three-dimensional). Roughness parameters of the 3D surface are also important in analyzing the mechanics of contact surfaces. Problems of mechanics of contact surfaces are related to accuracy of 3D surface roughness characteristic. One of the most important factors for 3D characteristics determination is the number of data points per x and y axes. With number of data points we understand its number in cut-off length. Number of data points have substantial influence on the accuracy of measurement results, measuring time and size of output data file (especially along the y-axis direction, where number of data points are number of parallel profiles). Number of data points must be optimal. Small number of data points lead to incorrect results and increase distribution amplitude, but too large number of data points do not enlarge range of fundamental information, but substantially increase measuring time. Therefore, we must find optimal number of data points per each surface processing method.
基金supported by the National Natural Science Foundation of China(20975011)"Chemical Grid Project"of Beijing University of Chemical Technology
文摘The human ether-a-go-go related gene (hERG) channel is responsible for the repolarization during the action potential, and blockage of that may result in severe cardiotoxicity and sudden death. In this study, a dataset containing 1969 compounds was compiled from literature and FDA-approved drugs. Using a support vector machine (SVM), two groups of computational models were built to distinguish whether a compound is a blocker or non-blocker of hERG potassium ion channel. These mod- els fit generally satisfactory. The 100 models built with MACCS fingerprints (Model Group A) showed an average accuracy of 90% and an average matthews correlation coefficient (MCC) value of 0.77 on the test sets. The 100 models built with selected MOE descriptors (Model Group B) showed an average accuracy of 89% and an average MCC value of 0.74 on the test sets. Molecular hydrophobicity and lipophilicity were found to be very important factors which lead to block the hERG potassium ion channel. Some other molecular properties such as electrostatic properties, features based on van der Waals surface area, the number of rigid bonds and molecular surface rugosity also played important roles in blocking bERG potassium ion channel.