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比伐卢定合成策略的选择及合成条件的优化
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作者 虞娉 杨祺 +1 位作者 王宇 王翠莲 《浙江中西医结合杂志》 2012年第5期412-413,F0003,共3页
比伐卢定是一种人工合成制备的含20个氨基酸的多肽,是凝血酶的二价抑制剂,主要用于心肌梗死急救、心脏手术、整形外科手术后深层静脉血栓的预防等。其序列是:D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-G... 比伐卢定是一种人工合成制备的含20个氨基酸的多肽,是凝血酶的二价抑制剂,主要用于心肌梗死急救、心脏手术、整形外科手术后深层静脉血栓的预防等。其序列是:D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH。 展开更多
关键词 比伐卢定 片段固液相合成 缩合试剂 替代度 裂解试剂
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Preparation and Commercial Application of ZHC-01 Hydrocracking Catalyst
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作者 Xu Xuejun Liu Dongxiang Wang Haitao Feng Xiaoping Wang Jifeng 《China Petroleum Processing & Petrochemical Technology》 SCIE CAS 2007年第2期43-47,共5页
The ZHC-01 hydrocracking catalyst, characterized by high hydrogenation activity, good selectivity for middle distillates, strong resistance to nitrogen poisoning, was prepared by co-gelling. The catalyst is not only s... The ZHC-01 hydrocracking catalyst, characterized by high hydrogenation activity, good selectivity for middle distillates, strong resistance to nitrogen poisoning, was prepared by co-gelling. The catalyst is not only suited to the single-stage hydrocracking process, but also to the first stage of serial hydrocracking process. In parallel with the fully loaded operation of the 1.4 Mt/a hydrocracking unit at the SINOPEC Qilu Petrochemical Company, a pilot test of the ZHC-01 catalyst was also carried out on the hydrocracking unit. The test results indicated that the activity, the yield of major target products and quality of the ZHC-01 catalyst could comply with the design requirements for the hydrocracking unit, and this catalyst could be applied in the hydrocracking unit. The commercial test results showed that the ZHC-01 catalyst, featuring good activity, stability, and flexibility in production, not only could meet the demand for producing environmentally friendly middle distillates, but could also increase the resource of optimized steam cracking feedstock. 展开更多
关键词 HYDROCRACKING CATALYST pilot plant test commercial application
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