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亚洲型和西方型多发性硬化髓磷脂少突胶质细胞糖蛋白微卫星等位基因多态性的比较 被引量:7
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作者 马建军 徐予明 +3 位作者 徐军 连亚军 西村公孝 齐田孝彦 《郑州大学学报(医学版)》 CAS 北大核心 2003年第4期506-508,共3页
目的 :比较亚洲型和西方型髓磷脂少突胶质细胞糖蛋白 (MOG)基因的多态性与比较亚洲型和西方型多发性硬化 (MS)患者。方法 :将 85例MS患者分为亚洲型 (4 0例 )和西方型 (4 5例 ) ,用微卫星法测定其MOG等位基因的多态性 ,并与 87例健康者 ... 目的 :比较亚洲型和西方型髓磷脂少突胶质细胞糖蛋白 (MOG)基因的多态性与比较亚洲型和西方型多发性硬化 (MS)患者。方法 :将 85例MS患者分为亚洲型 (4 0例 )和西方型 (4 5例 ) ,用微卫星法测定其MOG等位基因的多态性 ,并与 87例健康者 (对照组 )相比。结果 :MOG11/ 12等位基因与各型MS无关 (P >0 .0 5 ) ;亚洲型MSMOG5 1/ 5 2的 2 18bp等位基因频率显著高于西方型 ,西方型MS患者 2 18bp等位基因的频率显著低于对照组(P均 <0 .0 0 1) ;西方型MSMOG5 1/ 5 2的 2 2 2bp等位基因频率显著高于亚洲型和对照组 (P <0 .0 0 1~ 0 .0 5 ) ;亚洲型、西方型MS患者MOG5 1/ 5 2的 2 2 6bp等位基因频率均显著高于对照组 (P <0 .0 0 1~ 0 .0 0 5 )。 结论 :亚洲型和西方型是MS不同的临床亚型 ;MOG5 1/ 5 2的 2 2 2bp等位基因与西方型MS相关 ,与亚洲型MS无关 ;MOG5 1/ 5 2的 2 2 展开更多
关键词 亚洲 西方型 多发性硬化 髓磷脂少突胶质细胞糖蛋白 微卫星 等位基因多态性 比较
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亚洲型和西方型多发性硬化多形式脑诱发电位的比较 被引量:6
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作者 马建军 孙翠萍 +1 位作者 李六一 徐军 《中国临床康复》 CSCD 2003年第22期3062-3063,共2页
目的:探讨亚洲型和西方型多发性硬化(multiplesclerosis,MS)多形式脑诱发电位的差异。方法:对19例亚洲型和24例西方型MS患者进行了视觉诱发电位(visualevokedresponse,VEP)、脑干听觉诱发电位(brain-stemauditorye-vokedpotential,BAEP... 目的:探讨亚洲型和西方型多发性硬化(multiplesclerosis,MS)多形式脑诱发电位的差异。方法:对19例亚洲型和24例西方型MS患者进行了视觉诱发电位(visualevokedresponse,VEP)、脑干听觉诱发电位(brain-stemauditorye-vokedpotential,BAEP)和躯体感觉诱发电位(somatosensoryevokedpo-tential,SEP)的综合研究,并对两者的临床特点进行了比较。结果:亚洲型多发性硬化发病年龄犤(35±12)岁犦明显高于西方型犤(27±11)岁犦(t=2.3378,P<0.05)。EDSS评分在亚洲型MS(5.3±2.3)也明显高于西方型(3.8±2.1)(t=2.2304,P<0.05)。亚洲型MS的VEP异常率(89%)显著高于西方型(54%)(χ2=4.7053,P<0.05),而BAEP异常率低(42%)显著低于西方型(71%)(χ2=70.4663,P<0.001)。结论:亚洲型和西方型是多发性硬化的两种不同的临床亚型。 展开更多
关键词 亚洲多发性硬化 西方型多发性硬化 视觉诱发电位 脑干听觉诱发电位 躯体感觉诱发电位
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亚洲型和西方型多发性硬化患者脑诱发电位及HLA基因多态性的比较 被引量:7
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作者 马建军 孙翠萍 +1 位作者 李六一 齐田孝彦 《河南医学研究》 CAS 2004年第2期146-148,共3页
目的 :探讨亚洲型和西方型多发性硬化 (multiplesclerosis ,MS)多形式脑诱发电位和人类白细胞抗原(Humanleukocyteantigen ,HLA)基因多态性的差异。 方法 :将 80例MS患者分为亚洲型 ( 3 8例 )和西方型 ( 4 2例 )两组 ,分别进行视觉诱发... 目的 :探讨亚洲型和西方型多发性硬化 (multiplesclerosis ,MS)多形式脑诱发电位和人类白细胞抗原(Humanleukocyteantigen ,HLA)基因多态性的差异。 方法 :将 80例MS患者分为亚洲型 ( 3 8例 )和西方型 ( 4 2例 )两组 ,分别进行视觉诱发电位 (visualevokedpotentialS,VEPS)、脑干听觉诱发电位 (brainstemauditoryevokedpotentialS,BAEPS)和躯体感觉诱发电位 (somatosensoryevokedpotentials ,SEPS)检查 ;用改良的PCR 限制性片段长度多态性 (PCR RFLP)结合组间特异性引物法测定HLADRB1基因的多态性。结果 :亚洲型MS患者的VEP异常率显著高于西方型 (P <0 0 5 ) ,而BAEP异常率显著低于西方型 (P <0 0 0 1) ;HLA DRB1 15 0 1等位基因的频率在西方型MS显著高于健康对照组 (P <0 0 5 )。结论 :亚洲型和西方型是MS不同的临床亚型 ;HLA DRB1 15 0 1等位基因与西方型MS相关 。 展开更多
关键词 亚洲 西方型 多发性硬化 脑诱发电位 MS HLA基因 基因多态性 人类自细胞抗原 HLA
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亚洲型和西方型多发性硬化的研究进展 被引量:2
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作者 马建军 徐军 《实用诊断与治疗杂志》 2003年第6期476-478,共3页
多发性硬化(multiple sclerosis,MS)是一种常见的以中枢神经系统白质脱髓鞘病变为特点的自身免疫性疾病.MS病变在空间上的多发性(即散在分布于中枢神经系统的多数病灶)及其在时间上的多发性(即病程中的缓解复发),构成了其临床经过及症... 多发性硬化(multiple sclerosis,MS)是一种常见的以中枢神经系统白质脱髓鞘病变为特点的自身免疫性疾病.MS病变在空间上的多发性(即散在分布于中枢神经系统的多数病灶)及其在时间上的多发性(即病程中的缓解复发),构成了其临床经过及症状和体征的主要特点.西方人的MS以大脑、脑干病损为主(称为西方型MS),而日本和我国均发现脊髓和视神经受损害最常见(称为亚洲型MS).随着神经电生理学、分子生物学等学科的飞速发展,近年来对两型MS的研究也日趋深入,现综述如下. 展开更多
关键词 多发性硬化 诱发电位 基因多态性 亚洲 西方型
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融东西方教育模式,培养“T”型人才 被引量:35
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作者 林崇德 《北京师范大学学报(社会科学版)》 CSSCI 北大核心 2001年第1期5-11,共7页
“T”型人才资源的开发 ,将意味着全世界掀起一场教育变革。东西方教育各有各自的模式 ,于是培养出不同特点的人才 ;东西方教育模式是相通相融的 ,我们要根据这种互补性 ,扬长避短 ,培养学贯中西的人才 ;为了培养“T”型人才 ,应该在教... “T”型人才资源的开发 ,将意味着全世界掀起一场教育变革。东西方教育各有各自的模式 ,于是培养出不同特点的人才 ;东西方教育模式是相通相融的 ,我们要根据这种互补性 ,扬长避短 ,培养学贯中西的人才 ;为了培养“T”型人才 ,应该在教育思想、教育内容和教育方法上实行改革。培养“T”型人才 ,东方教育要改革 。 展开更多
关键词 东方教育模式 教育思想 人才观 教学评估体系 西方教育模式“T”人才 教育改革 教学改革 素质教育
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轴心时代的泛艺术三型
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作者 张法 《艺术学研究》 2021年第6期19-26,共8页
轴心时代,中国、西方、印度都产生了理性思想,从而产生了三种泛艺术类型:希腊的公民型泛艺术、中国的朝廷—士人型泛艺术、印度的宗教型泛艺术。希腊的泛艺术以技为核心,中国的泛艺术以文为核心,印度的泛艺术以舞为核心。一方面,艺术具... 轴心时代,中国、西方、印度都产生了理性思想,从而产生了三种泛艺术类型:希腊的公民型泛艺术、中国的朝廷—士人型泛艺术、印度的宗教型泛艺术。希腊的泛艺术以技为核心,中国的泛艺术以文为核心,印度的泛艺术以舞为核心。一方面,艺术具有相对独立的形态,与文化的其他方面有所区别;另一方面,艺术之名又包括了非艺术在其中,而且艺术的功能与文化的其他方面相关联。西方、中国、印度的泛艺术既有共同性,又有文化的独特性。 展开更多
关键词 轴心时代 西方型泛艺术 中国泛艺术 印度泛艺术
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我国军衔制与众不同
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《共产党员(下半月)》 2008年第11期54-54,共1页
我军实行的军衔制既不属于以苏联为代表的“东方型”,也不同于以美英为代表的“西方型”。我军1955年军衔制军官军衔等级为4等15级,而1988年实行新的军衔制时,军官军衔等级设置更简单一些,设3等11级——将官:一级上将、上将、中将... 我军实行的军衔制既不属于以苏联为代表的“东方型”,也不同于以美英为代表的“西方型”。我军1955年军衔制军官军衔等级为4等15级,而1988年实行新的军衔制时,军官军衔等级设置更简单一些,设3等11级——将官:一级上将、上将、中将、少将;校官:大校、上校、中校、少校; 展开更多
关键词 军衔制 “东方 西方型 等级设置 军官 上将 中将 少将
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作为艺理基础和核心的美学 被引量:6
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作者 张法 《艺术学研究》 2020年第3期22-35,共14页
现代以来的世界艺理,皆以美为核心。从而,美学或为艺术理论,或为艺术理论的基础。美在人类的工具制造和仪式形成中产生,演进到轴心时代,形成了西方的学科型美学和非西方的非学科型美学。西方的学科型美学为实体—区分型美学,非西方文化... 现代以来的世界艺理,皆以美为核心。从而,美学或为艺术理论,或为艺术理论的基础。美在人类的工具制造和仪式形成中产生,演进到轴心时代,形成了西方的学科型美学和非西方的非学科型美学。西方的学科型美学为实体—区分型美学,非西方文化的非学科型美学中,印度为"是—变—幻—空"型美学,中国为虚实—关联型美学。中国、西方、印度美学各有特色,在世界现代性复杂进程中,三大美学的互动、升级、演进,对世界艺理产生着重要的影响。 展开更多
关键词 作为艺理基础的美学 西方的实体—区分美学 印度的“是—变—幻—空”美学 中国的虚实—关联美学
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Model Analysis of the Relationship Between Strategic Organization Knowledge and the Use of Information Systems in Firm Performance in Brazil
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作者 Adilson Carlos Yoshikuni Alberto Luiz Albertin 《Chinese Business Review》 2014年第5期301-319,共19页
Information Technology (IT) consolidates as an essential element to support the business strategies to survive and rapidly adapts to changes in the competitive environment. This paper examines the impact of the use ... Information Technology (IT) consolidates as an essential element to support the business strategies to survive and rapidly adapts to changes in the competitive environment. This paper examines the impact of the use of information systems (IS) and strategic organization knowledge (SOK) on firm performance in 150 Brazilian companies. The study uses partial least squares structural equation modeling (PLS-SEM) and establishes models to express the relationship among the constructs examined. The study identifies that the direct influence of 1S use on performance is moderately significant. However, when mediated by orientation strategy, the total effect of IS use on firm performance is demonstrated to be highly significant. The model explains 54% of the variability of firm performance and confirms IS use as a fundamental resource to support strategic business processes. 展开更多
关键词 firm performance strategic organization knowledge (SOK) information systems (IS) use informationtechnology (IT)
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Symmetry Reductions of Cauchy Problems for Fourth-Order Quasi-Linear Parabolic Equations 被引量:2
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作者 李吉娜 张顺利 苏敬蕊 《Communications in Theoretical Physics》 SCIE CAS CSCD 2010年第1期28-36,共9页
This paper is devoted to studying symmetry reduction of Cauchy problems for the fourth-order quasi-linear parabolic equations that admit certain generalized conditional symmetries (GCSs). Complete group classificati... This paper is devoted to studying symmetry reduction of Cauchy problems for the fourth-order quasi-linear parabolic equations that admit certain generalized conditional symmetries (GCSs). Complete group classification results are presented, and some examples are given to show the main reduction procedure. 展开更多
关键词 fourth-order quasi-linear parabolic equation symmetry reduction Cauchy problem
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Simultaneous hybrid modeling of a nosiheptide fermentation process using particle swarm optimization 被引量:1
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作者 Qiangda Yang Hongbo Gao +1 位作者 Weijun Zhang Huimin Li 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2016年第11期1631-1639,共9页
Hybrid modeling approaches have recently been investigated as an attractive alternative to model fermentation processes. Normally, these approaches require estimation data to train the empirical model part of a hybrid... Hybrid modeling approaches have recently been investigated as an attractive alternative to model fermentation processes. Normally, these approaches require estimation data to train the empirical model part of a hybrid model. This may result in decreasing the generalization ability of the derived hybrid model. Therefore, a simultaneous hybrid modeling approach is presented in this paper. It transforms the training of the empirical model part into a dynamic system parameter identification problem, and thus allows training the empirical model part with only measured data. An adaptive escaping particle swarm optimization(AEPSO) algorithm with escaping and adaptive inertia weight adjustment strategies is constructed to solve the resulting parameter identification problem, and thereby accomplish the training of the empirical model part. The uniform design method is used to determine the empirical model structure. The proposed simultaneous hybrid modeling approach has been used in a lab-scale nosiheptide batch fermentation process. The results show that it is effective and leads to a more consistent model with better generalization ability when compared to existing ones. The performance of AEPSO is also demonstrated. 展开更多
关键词 Bioprocess Dynamic modeling Neural networks Optimization
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On The Cauchy Problem For Some Parabolic Fractional Partial Differential Equations With Time Delays
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作者 Mahmoud M.El-Borai Wagdy G.El-Sayed Faez N. Ghaffoori 《Journal of Mathematics and System Science》 2016年第5期194-199,共6页
The Cauchy problem for some parabolic fractional partial differential equation of higher orders and with time delays is considered. The existence and unique solution of this problem is studied. Some smoothness propert... The Cauchy problem for some parabolic fractional partial differential equation of higher orders and with time delays is considered. The existence and unique solution of this problem is studied. Some smoothness properties with respect to the parameters of these delay fractional differential equations are considered. 展开更多
关键词 Cauchy problem- fractional partial differential equations with time delays- successive approximations.
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Value-at-Risk Approach to Currency Crises: A Brazilian Example With the Central Bank and Currency Based Assets*
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作者 Marcelo Zeuli 《Chinese Business Review》 2013年第9期593-609,共17页
This paper uses a Value at Risk (VaR) approach to evaluate a country financial vulnerability, by analyzing the risk exposure of its Central Bank, as if their assets are subject to market risk. The Brazilian currency... This paper uses a Value at Risk (VaR) approach to evaluate a country financial vulnerability, by analyzing the risk exposure of its Central Bank, as if their assets are subject to market risk. The Brazilian currency exchange swaps contracts (USS/Brazilian Reais) are submitted to a delta-normal VaR method, in order to evaluate the market risk of each swaps series, by modeling the variance of the daily returns, from August 1999 to January 2003. All daily returns series exhibited heteroscedasticity in the conditional variance and sudden changes in the unconditional variance. The points of changes of the unconditional variance were determined through the Iterative Cumulative Sum of Squares (ICSS) algorithm, and the conditional variance was modeled with Markov-Switching-Generalized Autoregressive Conditional Heteroscedasticity (SWGARCH) in order to capture heteroscedasticity and regime change. The results lead to two main conclusions: First, a VaR model must incorporate heteroscedasticity and regime switching in order to describe the variance of the tested series, submitted to brisk changes of economic and political scenarios. Second, a volatility-based VaR do not necessarily generate forward-looking indicators, but rather coincident indicators of possible financial vulnerabilities. The future research will evolve towards evaluating the effects of the Basel III recommendations as if they could be applied to this crisis period. 展开更多
关键词 emerging markets market risk VOLATILITY GARCH models regime switching
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Managerial Compensation Program and Capital Structure: An Empirical Study of Brazilian Companies
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作者 Maria Aparecida Gouvea Jose Roberto F. Savoia Michele N. Juca Ligia N. C. Fonseca 《Journal of Modern Accounting and Auditing》 2012年第2期147-160,共14页
The agency theory indicates the existence of costs as a way to mitigate conflicts between shareholders and managers, including: managerial compensation program, acquisition of shares by managers, monitoring of execut... The agency theory indicates the existence of costs as a way to mitigate conflicts between shareholders and managers, including: managerial compensation program, acquisition of shares by managers, monitoring of executives, and controlling shareholders. This study aims to determine the relevance of some variables related to compensation programs and of other determinants of the corporate debt level. It has considered a sample of 89 firms, which were analyzed through logistic regression (cross section). The model created has indicated a level of predictive assertiveness of approximately 87%. 展开更多
关键词 managerial compensation programs agency conflicts logistic regression
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Estimation Methodology of Short-term Natural Rubber Price Forecasting Models
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作者 A.A. Khin M. Zainalabidin +2 位作者 S. Mad Nasir E.C.F. Chong A. Fatimah Mohamed 《Journal of Environmental Science and Engineering》 2011年第4期460-474,共15页
This study developed a short-term econometric model of world natural rubber price Standard Malaysia Rubber Grade 20 (SMR20). Both single and simultaneous equations were utilized using monthly data from January 1990-... This study developed a short-term econometric model of world natural rubber price Standard Malaysia Rubber Grade 20 (SMR20). Both single and simultaneous equations were utilized using monthly data from January 1990-December 2008 as estimation period and data from January 2009-June 2009 was used as an ex-ante forecast. The data were tested for unit root and Vector Error Correction and co-integration method was used to estimate the parameters of the model. The models specifications were developed in order to discover the inter-relationships between NR production, consumption and prices of SMR20 and to determine forecast price of SMR20. Comparative analysis between the single-equation specification and simultaneous supply-demand and price equation were made in terms of their estimation accuracy based on RMSE, MAE and (U-Thile) criteria. Ex-ante forecasts was carried out for the period of January 2009-June 2009. The results revealed that the values of the RMSE, MAE and U of simultaneous supply-demand and price equations model were comparatively smaller than the values generated by the single-equation model. These statistics suggest that the simultaneous equation of supply-demand and price model is more accurate and efficient measure in terms of its statistical criteria than the single-equation model in predicting the price of SMR20 in the next 6 months. 展开更多
关键词 Supply-demand and price model econometric forecasting single equation natural rubber price
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Effect of Socio-Economic Variables on Fish Production of Small Farmers in Tocantins State, Brazil
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作者 Roberto Manolio Valladao Flores Manoel Xavier Pedroza Filho 《Journal of Agricultural Science and Technology(B)》 2014年第4期331-339,共9页
Fish farming is a strategic activity for both the economy and food security of the Tocantins state. Nowadays, there are about eighty small fish farmers in the region of Divin6polis in Tocantins state. The technologica... Fish farming is a strategic activity for both the economy and food security of the Tocantins state. Nowadays, there are about eighty small fish farmers in the region of Divin6polis in Tocantins state. The technological level of fish farmers is low and it was found that only 30% of farmers could ever get to the point of selling fish. Therefore, the objective of this paper is to investigate which socioeconomic factors have influence on the fact of fish farmers in the region of Divin6polis and in Tocantins state reach a level of efficiency in production enough that the fish can be good for sale in the local market. To estimate this relation the logit model was chosen, with methodology based on the empirical model used in Musaba and Namukwambi. Following the production of fish farms in the Western of Tocantins state, the collect of the data, during 2012, were conduct with interviews of 30 fish farms, visiting them in their homes and applying a questionnaire. Through the use of econometric models of probability for limited dependent variables, it was found that factors such as participation in federal programs to transfer income, total area of water and production in ponds are key factors in determining the likelihood of producer to sell fish. 展开更多
关键词 AQUACULTURE small fish farming LOGIT Tocantins state.
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1927-1949年国民政府军人抚恤观念之流变 被引量:8
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作者 李翔 陈宏明 《军事历史研究》 北大核心 2008年第3期125-132,共8页
军人抚恤是古今中外各国政府都必须面对的难题。经过长期的历史沿革,西方出现义务型抚恤观念,中国形成传统的恩赏型抚恤观念。南京国民政府建立后,军人抚恤观念在吸收西方现代抚恤因素的基础上,在受到多次冲击的前提下,也经历着鲜明的... 军人抚恤是古今中外各国政府都必须面对的难题。经过长期的历史沿革,西方出现义务型抚恤观念,中国形成传统的恩赏型抚恤观念。南京国民政府建立后,军人抚恤观念在吸收西方现代抚恤因素的基础上,在受到多次冲击的前提下,也经历着鲜明的变迁过程,即由传统的恩赏型抚恤观念向现代义务型抚恤观念转变。 展开更多
关键词 军人抚恤 传统恩赏 西方义务 南京国民政府
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由中西印哲学而来的语言差异谈中国的文化自觉——中西印哲学思想和语言特质比较(下) 被引量:1
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作者 张法 《探索与争鸣》 CSSCI 北大核心 2018年第2期16-23,共8页
由中西印哲学思想而来的语言各有特点。西方在重空间轻时间之基础上,为确定事物和世界,从各种to be(是)而来的本质之being(是),构成其语言的定义型特色,并由之形成了语言的主谓结构和主句从句的几何之美。印度在重时间轻空间的基础上,... 由中西印哲学思想而来的语言各有特点。西方在重空间轻时间之基础上,为确定事物和世界,从各种to be(是)而来的本质之being(是),构成其语言的定义型特色,并由之形成了语言的主谓结构和主句从句的几何之美。印度在重时间轻空间的基础上,为确定事物和世界,而把"是"分为本质之as(是)和现象之bhū(是),构成了其语言的反定义特色,形成以动词词根为基础的语言体系。中国在时空兼顾的基础上,为确定事物和世界,产生了"……者……也"结构及其简化形式,构成其语言的非定义特色,形成了词—语—句的灵动体系。汉语在由古代汉语向现代汉语的转型中,利弊皆有,在全球化时代如何提升汉语,成为文化自觉的问题之一。 展开更多
关键词 西方定义语言特色 印度反定义语言特色 中国非定义语言特色 中西印语言比较文化自觉
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浅谈两种食物结构的特点
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作者 丛恕增 《食品科技》 CAS 北大核心 1999年第1期51-51,共1页
所谓食物结构,就是指我们每天所吃的食物是以动物食物为主还是以植物性食物为主,以及这些食物是如何搭配的。一个国家、一个民族的食物结构是由传统的饮食习惯、宗教信仰以及社会经济发展、人口、资源及消费能力所决定的。当前世界上... 所谓食物结构,就是指我们每天所吃的食物是以动物食物为主还是以植物性食物为主,以及这些食物是如何搭配的。一个国家、一个民族的食物结构是由传统的饮食习惯、宗教信仰以及社会经济发展、人口、资源及消费能力所决定的。当前世界上的食物结构、基本上可分为两种类型,... 展开更多
关键词 西方型 东方 食物结构 动物性食物 植物性食物
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Optimal Controls of Nonlinear Evolution Inclusions withPseudomonotone Operator
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作者 张著洪 《Journal of Mathematical Research and Exposition》 CSCD 北大核心 2002年第2期229-237,共9页
In this paper, we study the optimal control problem of nonlinear differentialinclusions with principle operator being pseudomonotone. First, we give some propertiesof solutions of certain evolution equations. Further,... In this paper, we study the optimal control problem of nonlinear differentialinclusions with principle operator being pseudomonotone. First, we give some propertiesof solutions of certain evolution equations. Further, we prove the existence of admissibletrajectories for evolution inclusions. Then, we extend the Fillipov's selection theoremand discuss a general Lagrange type optimal control problem. Finally, we present anexample that demonstrates the appplicability of our results. 展开更多
关键词 evolution inclusion set-valued analysis pseudomonotone operator upper semicontinuity support function parabolic system.
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