Weed control is a crucial factor for maintaining establishment and herbage production in dwarf variety of late-heading type （DL） napiergrass （Pennisetum purpureum Schumach） in southern Kyushu, Japan. This study wa...Weed control is a crucial factor for maintaining establishment and herbage production in dwarf variety of late-heading type （DL） napiergrass （Pennisetum purpureum Schumach） in southern Kyushu, Japan. This study was aimed to verify the weeding-effect on dry matter （DM） production in the farm level and to examine the effect of several weed control, i.e. mixed sowing of annual setaria （abbreviated as S）, which has no regrowth ability after stem-elongation, paper-mulching （as P） and hand-weeding （as ＋W）, compared with no-weeding （as -W） on DM yield and quality of DL napiergrass in two years. Weed control practices significantly （P 〈 0.05） promoted several plant growth attributes in DL napiergrass, compared with no-weeding both in the farm and experimental levels. Paper-mulchidng （P-W or P＋S-W） had highest yields among several practices in both years. Setaria-sowing ha a partially mitigating effect of weed damage on DM production of DL napiergrass, while additive DM gain from setaria could compensate the yield decrease in DL napiergrass and reduce herbicide cost. Neither digestibility nor crude protein was affected by any weed control in either year. Thus, paper-mulching and annual setaria-sowing could be effective alternative practices for weed control of this species.展开更多
Nanoparticles can be enriched at tumor site and improve the therapeutic efficacy of many chemother- apy drugs with the well-known enhanced permeability and retention （EPR） effect. While conventional preparations of ...Nanoparticles can be enriched at tumor site and improve the therapeutic efficacy of many chemother- apy drugs with the well-known enhanced permeability and retention （EPR） effect. While conventional preparations of materials for nanoscale drug delivery system mainly focused on chemical synthesis, recently the combination of synthetic carrier and natural biomimetic carrier has gained more and more attention. As a new generation of biomimetic nanoparticles, cell membrane-coated nanoparticles combine the complex biological functions of natural membranes and the physicochemical properties of synthetic nanomaterials for a more effective drug delivery. Herein, we briefly review the recent advances on cell membrane-coated nanoparticles for tumor-targeted drug delivery via the prolonging systemic circulation lifetime and the active targeting effect. Since the preferential accumulation of cell membrane-coated nanopar- ticles in tumor site, they are able to improve the therapeutic efficacy of conventional chemotherapy drugs in antitumor treatment as well as to reduce the systemic toxicity. We also introduce a systematic targeted strategy for the promising application of this platform on brain tumors.展开更多
文摘Weed control is a crucial factor for maintaining establishment and herbage production in dwarf variety of late-heading type （DL） napiergrass （Pennisetum purpureum Schumach） in southern Kyushu, Japan. This study was aimed to verify the weeding-effect on dry matter （DM） production in the farm level and to examine the effect of several weed control, i.e. mixed sowing of annual setaria （abbreviated as S）, which has no regrowth ability after stem-elongation, paper-mulching （as P） and hand-weeding （as ＋W）, compared with no-weeding （as -W） on DM yield and quality of DL napiergrass in two years. Weed control practices significantly （P 〈 0.05） promoted several plant growth attributes in DL napiergrass, compared with no-weeding both in the farm and experimental levels. Paper-mulchidng （P-W or P＋S-W） had highest yields among several practices in both years. Setaria-sowing ha a partially mitigating effect of weed damage on DM production of DL napiergrass, while additive DM gain from setaria could compensate the yield decrease in DL napiergrass and reduce herbicide cost. Neither digestibility nor crude protein was affected by any weed control in either year. Thus, paper-mulching and annual setaria-sowing could be effective alternative practices for weed control of this species.
基金supported by the National Basic Research Program of China (2013CB932500)the National Natural Science Foundation of China (81273458 and 81473149)
文摘Nanoparticles can be enriched at tumor site and improve the therapeutic efficacy of many chemother- apy drugs with the well-known enhanced permeability and retention （EPR） effect. While conventional preparations of materials for nanoscale drug delivery system mainly focused on chemical synthesis, recently the combination of synthetic carrier and natural biomimetic carrier has gained more and more attention. As a new generation of biomimetic nanoparticles, cell membrane-coated nanoparticles combine the complex biological functions of natural membranes and the physicochemical properties of synthetic nanomaterials for a more effective drug delivery. Herein, we briefly review the recent advances on cell membrane-coated nanoparticles for tumor-targeted drug delivery via the prolonging systemic circulation lifetime and the active targeting effect. Since the preferential accumulation of cell membrane-coated nanopar- ticles in tumor site, they are able to improve the therapeutic efficacy of conventional chemotherapy drugs in antitumor treatment as well as to reduce the systemic toxicity. We also introduce a systematic targeted strategy for the promising application of this platform on brain tumors.
