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超声乳化联合小梁切除术治疗青光眼合并白内障患者的效果 被引量:2
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作者 吉宏程 万红霞 《中国民康医学》 2021年第6期15-17,共3页
目的:探讨超声乳化联合小梁切除术治疗青光眼合并白内障患者的效果。方法:选取86例(95眼)青光眼合并白内障患者作为研究对象,按随机数字表法将其分为对照组43例(47眼)与观察组43例(48眼)。对照组采用小梁切除术联合丝裂霉素C治疗,观察... 目的:探讨超声乳化联合小梁切除术治疗青光眼合并白内障患者的效果。方法:选取86例(95眼)青光眼合并白内障患者作为研究对象,按随机数字表法将其分为对照组43例(47眼)与观察组43例(48眼)。对照组采用小梁切除术联合丝裂霉素C治疗,观察组采用超声乳化联合小梁切除术治疗,比较两组手术前后视力水平、眼压水平和并发症发生率。结果:观察组术后1、6个月视力水平均优于对照组,差异有统计学意义(P<0.05);观察组术后1、6个月眼压水平均低于对照组,差异有统计学意义(P<0.05);观察组术后并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论:超声乳化联合小梁切除术治疗青光眼合并白内障患者可提高视力水平,降低眼压水平和并发症发生率,其效果优于小梁切除术联合丝裂霉素C治疗。 展开更多
关键词 超声乳化 小梁切除术 青光眼 白内障 视力:眼压
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Pressure balance and imbalance in the optic nerve chamber: The Beijing Intracranial and Intraocular Pressure (iCOP) Study 被引量:13
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作者 Ruowu Hou Zheng Zhang +11 位作者 Diya Yang Huaizhou Wang Weiwei Chen Zhen Li Jinghong Sang Sumeng Liu Yiwen Cao Xiaobin Xie Ruojing Ren Yazhuo Zhang Bernhard A. Sabel Ningli Wang 《Science China(Life Sciences)》 SCIE CAS CSCD 2016年第5期495-503,共9页
To determine the interdependence of intracranial pressure(ICP) and intraocular pressure(IOP) and how it affects optic nerve pressures, eight normal dogs were examined using pressure-sensing probes implanted into the l... To determine the interdependence of intracranial pressure(ICP) and intraocular pressure(IOP) and how it affects optic nerve pressures, eight normal dogs were examined using pressure-sensing probes implanted into the left ventricle, lumbar cistern, optic nerve subarachnoid space in the left eye, and anterior chamber in the left eye. This allowed ICP, lumbar cistern pressure(LCP), optic nerve subarachnoid space pressure(ONSP) and IOP to be simultaneously recorded. After establishing baseline pressure levels, pressure changes that resulted from lowering ICP(via shunting cerebrospinal fluid(CSF) from the ventricle) were recorded. At baseline, all examined pressures were different(ICP>LCP>ONSP), but correlated(P<0.001). As ICP was lowered during CSF shunting, IOP also dropped in a parallel time course so that the trans-lamina cribrosa gradient(TLPG) remained stable(ICP-IOP dependent zone). However, once ICP fell below a critical breakpoint, ICP and IOP became uncoupled and TLPG changed as ICP declined(ICP-IOP independent zone). The optic nerve pressure gradient(ONPG) and trans-optic nerve pressure gradient(TOPG) increased linearly as ICP decreased through both the ICP-IOP dependent and independent zones. We conclude that ICP and IOP are coupled in a specific pressure range, but when ICP drops below a critical point, IOP and ICP become uncoupled and TLPG increases. When ICP drops, a rise in the ONPG and TOPG creates more pressure and reduces CSF flow around the optic nerve. This change may play a role in the development and progression of various ophthalmic and neurological diseases, including glaucoma. 展开更多
关键词 GLAUCOMA optic neuropathy trans-lamina cribrosa pressure gradient (TLPG) trans-optic canal pressure gradient(TCPG) trans-optic nerve pressure gradient (TOPG) optic nerve pressure gradient (ONPG)
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