视网膜色素变性(RP)是最常见的遗传性视网膜疾病之一,具有较高的全球发病率。其潜在的病理机制涉及视神经的退行性改变和视网膜的逐渐损伤,首先表现为杆状感光细胞的损失,随后影响锥状感光细胞。RP的发病机制复杂,目前尚无单一的有效治...视网膜色素变性(RP)是最常见的遗传性视网膜疾病之一,具有较高的全球发病率。其潜在的病理机制涉及视神经的退行性改变和视网膜的逐渐损伤,首先表现为杆状感光细胞的损失,随后影响锥状感光细胞。RP的发病机制复杂,目前尚无单一的有效治疗方法。中医学以整体观念和辨证论治为基础,在维持视功能、延缓疾病进展等方面展现出一定的优势。本文对近年来中医药治疗RP的相关研究进行了回顾,重点从RP的发病机制、中药治疗、针刺疗法以及针药结合等方面进行综述,并对中医药治疗RP的不足与未来发展方向提出了展望。Retinitis pigmentosa (RP) is one of the most common inherited retinal diseases, with a high global incidence rate. The underlying pathological mechanisms involve degenerative changes in the optic nerve and progressive damage to the retina, initially manifesting as loss of rod photoreceptors, followed by cone photoreceptors. The pathogenesis of RP is complex, and no single effective treatment currently exists. Traditional Chinese medicine (TCM), based on the holistic concept and syndrome differentiation, demonstrates certain advantages in maintaining visual function and slowing disease progression. This paper reviews recent studies on the treatment of RP with TCM, focusing on the pathogenesis of RP, herbal medicine treatment, acupuncture therapy, and the combination of acupuncture and herbal medicine. It also provides an outlook on the shortcomings of TCM treatment for RP and future development directions.展开更多
文摘视网膜色素变性(RP)是最常见的遗传性视网膜疾病之一,具有较高的全球发病率。其潜在的病理机制涉及视神经的退行性改变和视网膜的逐渐损伤,首先表现为杆状感光细胞的损失,随后影响锥状感光细胞。RP的发病机制复杂,目前尚无单一的有效治疗方法。中医学以整体观念和辨证论治为基础,在维持视功能、延缓疾病进展等方面展现出一定的优势。本文对近年来中医药治疗RP的相关研究进行了回顾,重点从RP的发病机制、中药治疗、针刺疗法以及针药结合等方面进行综述,并对中医药治疗RP的不足与未来发展方向提出了展望。Retinitis pigmentosa (RP) is one of the most common inherited retinal diseases, with a high global incidence rate. The underlying pathological mechanisms involve degenerative changes in the optic nerve and progressive damage to the retina, initially manifesting as loss of rod photoreceptors, followed by cone photoreceptors. The pathogenesis of RP is complex, and no single effective treatment currently exists. Traditional Chinese medicine (TCM), based on the holistic concept and syndrome differentiation, demonstrates certain advantages in maintaining visual function and slowing disease progression. This paper reviews recent studies on the treatment of RP with TCM, focusing on the pathogenesis of RP, herbal medicine treatment, acupuncture therapy, and the combination of acupuncture and herbal medicine. It also provides an outlook on the shortcomings of TCM treatment for RP and future development directions.
文摘采用 PVEP 记录技术对经中医药治疗的视网膜色素变性(RP)54例患者的106只眼进行了研究。结果表明:(1)PVEP 在视网膜色素变性眼较正常对照组检出率降低,治疗后检出率获一定程度回升;(2)各型RP 眼的 PVEP 反应振幅与潜伏期在治疗后发生不同程度的改善;(3)不同 SF 的 PVEP 检测在 RP 眼具有不同的统计学意义。提示中医药治疗可改善 RP 眼视网膜中心视功能,对延缓病情进程,保持中心视力具有一定的临床意义。
