AIM To evaluate the usefulness of different parameters to differentiate Crohn's disease(CD) from primary intestinal lymphoma(PIL).METHODS The medical records of 85 patients with CD and 56 patients with PIL were re...AIM To evaluate the usefulness of different parameters to differentiate Crohn's disease(CD) from primary intestinal lymphoma(PIL).METHODS The medical records of 85 patients with CD and 56 patients with PIL were reviewed retrospectively. Demographic, clinical, laboratory, endoscopic, and computed tomographic enterography(CTE) parameters were collected. The univariate value of each parameter was analyzed. A differentiation model was established by pooling all the valuable parameters. Diagnostic efficacy was analyzed, and a receiver operating characteristic(ROC) curve was plotted.RESULTS The demographic and clinical parameters that showed significant values for differentiating CD from PIL included age of onset, symptom duration, presence of diarrhea, abdominal mass, and perianal lesions(P < 0.05). Elevated lactate dehydrogenase and serum β2-microglobulin levels suggested a PIL diagnosis(P < 0.05). The endoscopic parameters that showed significant values for differentiating CD from PIL included multiple-site lesions, longitudinal ulcer, irregular ulcer,and intraluminal proliferative mass(P < 0.05). The CTE parameters that were useful in the identification of the two conditions included involvement of ≤ 3 segments, circular thickening of the bowel wall, wall thickness > 8 mm, aneurysmal dilation, stricture with proximal dilation, "comb sign", mass showing the "sandwich sign", and intussusceptions(P < 0.05). The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of the differentiation model were 91.8%, 96.4%, 93.6%, 97.5%, and 88.5%, respectively. The cutoff value was 0.5. The area under the ROC curve was 0.989.CONCLUSION The differentiation model that integrated the various parameters together may yield a high diagnostic efficacy in the differential diagnosis between CD and PIL.展开更多
Biliary strictures are considered indeterminate when basic work-up, including transabdominal imaging and endoscopic retrograde cholangiopancreatography with routine cytologic brushing, are non-diagnostic. Indeterminat...Biliary strictures are considered indeterminate when basic work-up, including transabdominal imaging and endoscopic retrograde cholangiopancreatography with routine cytologic brushing, are non-diagnostic. Indeterminate biliary strictures can easily be mischaracterized which may dramatically affect patient's outcome. Early and accurate diagnosis of malignancy impacts not only a patient's candidacy for surgery, but also potential timely targeted chemotherapies. A significant portion of patients with indeterminate biliary strictures have benign disease and accurate diagnosis is, thus, paramount to avoid unnecessary surgery. Current sampling strategies have suboptimal accuracy for the diagnosis of malignancy. Emerging data on other diagnostic modalities, such as ancillary cytology techniques, single operator cholangioscopy, and endoscopic ultrasonography-guided fine needle aspiration, revealed promising results with much improved sensitivity.展开更多
This paper introduces the techniques of direct volume rendering in VTK and discusses ray-casting--the most popular technique of direct volume rendering. The visualizations for medical volumetric data by three function...This paper introduces the techniques of direct volume rendering in VTK and discusses ray-casting--the most popular technique of direct volume rendering. The visualizations for medical volumetric data by three functions of raycasting are offered. Visualization effects prove that VTK is easy to get satisfied resuits with good quality in short time.展开更多
Recent advances in endoscopic imaging techniques have revolutionized the diagnostic approach of patients with inflammatory bowel disease(IBD).New,emerging endoscopic imaging techniques visualized a plethora of new muc...Recent advances in endoscopic imaging techniques have revolutionized the diagnostic approach of patients with inflammatory bowel disease(IBD).New,emerging endoscopic imaging techniques visualized a plethora of new mucosal details even at the cellular and subcellular level.This review offers an overview about new endoscopic techniques,including chromoendoscopy,magnification endoscopy,spectroscopy,confocal laser endomicroscopy and endocytoscopy in the face of IBD.展开更多
Two classification and identification methods based on pattern discrimination models and the majority-vote technique were investigated for implementing a World Wide Web-based system for the identification of rice dise...Two classification and identification methods based on pattern discrimination models and the majority-vote technique were investigated for implementing a World Wide Web-based system for the identification of rice diseases. The experiment was carried out using color and shape patterns in 425 images of three rice diseases, which were classified into four classes: two classes of leaf blast, and one class each of sheath blight and brown spot. A method consisting of two discrimination steps involving application of multiple discrimination models of a support vector machine gave the best result because of its capacity to evaluate the similarity of disease types. This accuracy of the method was 88% for leaf blast (A-type), 94% for sheath blight, and 80% for leaf blast (B-type) and brown spot; on average, the accuracy of this method was 5% greater than that of the other method when three classes were used in the model. Although the accuracy of both methods was inadequate, the results of this study show that it is possible to estimate the least number of possible or similar diseases from a large number of diseases. Therefore, we conclude that there is merit in grouping classes into subgroups rather than attempting to discriminate between all classes simultaneously and that these methods are effective in identifying diseases for web-based diagnosis.展开更多
Three-dimensional medical image visualization becomes an essential part for medical field, including computer aided diagnosis, surgery planning and simulation, artificial limb surgery, radiotherapy planning, and teach...Three-dimensional medical image visualization becomes an essential part for medical field, including computer aided diagnosis, surgery planning and simulation, artificial limb surgery, radiotherapy planning, and teaching etc. In this paper, marching cubes algorithm is adopted to reconstruct the 3-D images for the CT image sequence in DICOM format under theVC++6.0 and the visual package VTK platform. The relatively simple interactive operations such as rotation and transfer can be realized on the platform. Moreover, the normal vector and interior point are calculated to form the virtual clipping plane, which is then used to incise the 3-D object. Information of the virtual slice can be obtained, in the mean while the virtual slice images are displayed on the screen. The technique can realize the real time interaction extraction of virtual slice on 3-D CT image. The cuboids structured can be zoomed, moved and eircumrotated by operating mouse to incise the 3-D reconstruction object. Real time interaction can be realized by clipping the reconstruction object. The coordinates can be acquired by the mouse clicking in the 3D space, to realize the point mouse pick-up as well angle and distance interactive measurement. We can get quantitative information about 3-D images through measurement.展开更多
Monitoring the operational state of sensors promptly and the accurate diagnosis of faults are essential. This paper proposes an improved fault diagnosis scheme for sensors, which includes both fault detection and faul...Monitoring the operational state of sensors promptly and the accurate diagnosis of faults are essential. This paper proposes an improved fault diagnosis scheme for sensors, which includes both fault detection and fault identification. Firstly, trend analysis combined with least squares support vector machine(TA-LSSVM) method is proposed and implemented to detect faults. Secondly, an improved error correcting output coding-support vector machine(ECOC-SVM) based fault identification method is proposed to distinguish different sensor failure modes. To demonstrate the effectiveness of the proposed scheme, experiments are conducted with an MTi-series sensor, and some comparisons are made with other fault identification methods. The experimental results demonstrate that the proposed fault diagnosis scheme offers an essential improvement with detection real-time property and better identification accuracy.展开更多
Visible Human Project (VHP)' was initiated by US National Library of Medicine in 1989, and in August 1991, the library signed a contract with Health Science Center of the University of Colorado to formally carry o...Visible Human Project (VHP)' was initiated by US National Library of Medicine in 1989, and in August 1991, the library signed a contract with Health Science Center of the University of Colorado to formally carry out the project. Accordingly, research team at the University of Colorado collected a structural data set of human body after obtaining successive sectional images. A digital image data set of a complete human male cadaver was acquired and made available for public use in November 1994, which aroused worldwide enthusiasm in this field, and remarkable social and economic benefit has been gained. Thereafter, some countries initiated their visible human project one after another. Korea started 5-year' Visible Korean Human (VKH)' project (Mar. 2000-Feb. 2005) in 2000, and the first data set derived from a patient with cerebroma was acquired in 2001. China began its project in 1999. The first data set of Chinese visible human was obtained at The Third Military Medical University in October 2002. Before that, by utilizing data made public by US VHP, Chinese scientists in informatics had exerted themselves on preliminary work to pave the way for further achievement. Now that VHP research is such a promising scientific field to meet the need of digital era and will be increasingly common in many areas related with structure and function of human body, the deployment of Chinese Visible Human Project (CVHP) is of great strategic significance with regard to science and technology.展开更多
文摘AIM To evaluate the usefulness of different parameters to differentiate Crohn's disease(CD) from primary intestinal lymphoma(PIL).METHODS The medical records of 85 patients with CD and 56 patients with PIL were reviewed retrospectively. Demographic, clinical, laboratory, endoscopic, and computed tomographic enterography(CTE) parameters were collected. The univariate value of each parameter was analyzed. A differentiation model was established by pooling all the valuable parameters. Diagnostic efficacy was analyzed, and a receiver operating characteristic(ROC) curve was plotted.RESULTS The demographic and clinical parameters that showed significant values for differentiating CD from PIL included age of onset, symptom duration, presence of diarrhea, abdominal mass, and perianal lesions(P < 0.05). Elevated lactate dehydrogenase and serum β2-microglobulin levels suggested a PIL diagnosis(P < 0.05). The endoscopic parameters that showed significant values for differentiating CD from PIL included multiple-site lesions, longitudinal ulcer, irregular ulcer,and intraluminal proliferative mass(P < 0.05). The CTE parameters that were useful in the identification of the two conditions included involvement of ≤ 3 segments, circular thickening of the bowel wall, wall thickness > 8 mm, aneurysmal dilation, stricture with proximal dilation, "comb sign", mass showing the "sandwich sign", and intussusceptions(P < 0.05). The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of the differentiation model were 91.8%, 96.4%, 93.6%, 97.5%, and 88.5%, respectively. The cutoff value was 0.5. The area under the ROC curve was 0.989.CONCLUSION The differentiation model that integrated the various parameters together may yield a high diagnostic efficacy in the differential diagnosis between CD and PIL.
文摘Biliary strictures are considered indeterminate when basic work-up, including transabdominal imaging and endoscopic retrograde cholangiopancreatography with routine cytologic brushing, are non-diagnostic. Indeterminate biliary strictures can easily be mischaracterized which may dramatically affect patient's outcome. Early and accurate diagnosis of malignancy impacts not only a patient's candidacy for surgery, but also potential timely targeted chemotherapies. A significant portion of patients with indeterminate biliary strictures have benign disease and accurate diagnosis is, thus, paramount to avoid unnecessary surgery. Current sampling strategies have suboptimal accuracy for the diagnosis of malignancy. Emerging data on other diagnostic modalities, such as ancillary cytology techniques, single operator cholangioscopy, and endoscopic ultrasonography-guided fine needle aspiration, revealed promising results with much improved sensitivity.
基金The author gratefully acknowledges the support of Youth for NWPUTeachers Scientific and Technological Innovation Foundation (5210102-0800-M016206)This work is supported by a grant for PH.D Site from Chinese Educational Department (20040699015)The authors are thankful to Guiqing He, PhD and Chongyang Hao, professor for many help and interesting discussions.
文摘This paper introduces the techniques of direct volume rendering in VTK and discusses ray-casting--the most popular technique of direct volume rendering. The visualizations for medical volumetric data by three functions of raycasting are offered. Visualization effects prove that VTK is easy to get satisfied resuits with good quality in short time.
文摘Recent advances in endoscopic imaging techniques have revolutionized the diagnostic approach of patients with inflammatory bowel disease(IBD).New,emerging endoscopic imaging techniques visualized a plethora of new mucosal details even at the cellular and subcellular level.This review offers an overview about new endoscopic techniques,including chromoendoscopy,magnification endoscopy,spectroscopy,confocal laser endomicroscopy and endocytoscopy in the face of IBD.
文摘Two classification and identification methods based on pattern discrimination models and the majority-vote technique were investigated for implementing a World Wide Web-based system for the identification of rice diseases. The experiment was carried out using color and shape patterns in 425 images of three rice diseases, which were classified into four classes: two classes of leaf blast, and one class each of sheath blight and brown spot. A method consisting of two discrimination steps involving application of multiple discrimination models of a support vector machine gave the best result because of its capacity to evaluate the similarity of disease types. This accuracy of the method was 88% for leaf blast (A-type), 94% for sheath blight, and 80% for leaf blast (B-type) and brown spot; on average, the accuracy of this method was 5% greater than that of the other method when three classes were used in the model. Although the accuracy of both methods was inadequate, the results of this study show that it is possible to estimate the least number of possible or similar diseases from a large number of diseases. Therefore, we conclude that there is merit in grouping classes into subgroups rather than attempting to discriminate between all classes simultaneously and that these methods are effective in identifying diseases for web-based diagnosis.
基金National 973 Basic Research Program of Chinagrant number:2010CB732600+4 种基金Major Research Equipment Fund of the Chinese Academy of Sciences and Knowledge Innovation Project of the Chinese Academy of Sciences,2008 Shenzhen Controversial Technology Innovation Research Projectsgrant number:FG200805230224AConcentration plan of innovation sources of Shenzhen-R&D projects of international cooperation on science and technologygrant number:ZYA200903260065ANatural Science Foundation of Guangdong Province,China 8478922035-X0007007
文摘Three-dimensional medical image visualization becomes an essential part for medical field, including computer aided diagnosis, surgery planning and simulation, artificial limb surgery, radiotherapy planning, and teaching etc. In this paper, marching cubes algorithm is adopted to reconstruct the 3-D images for the CT image sequence in DICOM format under theVC++6.0 and the visual package VTK platform. The relatively simple interactive operations such as rotation and transfer can be realized on the platform. Moreover, the normal vector and interior point are calculated to form the virtual clipping plane, which is then used to incise the 3-D object. Information of the virtual slice can be obtained, in the mean while the virtual slice images are displayed on the screen. The technique can realize the real time interaction extraction of virtual slice on 3-D CT image. The cuboids structured can be zoomed, moved and eircumrotated by operating mouse to incise the 3-D reconstruction object. Real time interaction can be realized by clipping the reconstruction object. The coordinates can be acquired by the mouse clicking in the 3D space, to realize the point mouse pick-up as well angle and distance interactive measurement. We can get quantitative information about 3-D images through measurement.
基金supported in part by the National Natural Science Foundation of China under Grant Nos.61304254,61321002 and 61120106010the Key Exploration Project under Grant No.7131253
文摘Monitoring the operational state of sensors promptly and the accurate diagnosis of faults are essential. This paper proposes an improved fault diagnosis scheme for sensors, which includes both fault detection and fault identification. Firstly, trend analysis combined with least squares support vector machine(TA-LSSVM) method is proposed and implemented to detect faults. Secondly, an improved error correcting output coding-support vector machine(ECOC-SVM) based fault identification method is proposed to distinguish different sensor failure modes. To demonstrate the effectiveness of the proposed scheme, experiments are conducted with an MTi-series sensor, and some comparisons are made with other fault identification methods. The experimental results demonstrate that the proposed fault diagnosis scheme offers an essential improvement with detection real-time property and better identification accuracy.
文摘Visible Human Project (VHP)' was initiated by US National Library of Medicine in 1989, and in August 1991, the library signed a contract with Health Science Center of the University of Colorado to formally carry out the project. Accordingly, research team at the University of Colorado collected a structural data set of human body after obtaining successive sectional images. A digital image data set of a complete human male cadaver was acquired and made available for public use in November 1994, which aroused worldwide enthusiasm in this field, and remarkable social and economic benefit has been gained. Thereafter, some countries initiated their visible human project one after another. Korea started 5-year' Visible Korean Human (VKH)' project (Mar. 2000-Feb. 2005) in 2000, and the first data set derived from a patient with cerebroma was acquired in 2001. China began its project in 1999. The first data set of Chinese visible human was obtained at The Third Military Medical University in October 2002. Before that, by utilizing data made public by US VHP, Chinese scientists in informatics had exerted themselves on preliminary work to pave the way for further achievement. Now that VHP research is such a promising scientific field to meet the need of digital era and will be increasingly common in many areas related with structure and function of human body, the deployment of Chinese Visible Human Project (CVHP) is of great strategic significance with regard to science and technology.